Guillaume Costa

ORCID: 0009-0008-9913-459X
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About
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Research Areas
  • Fluid Dynamics and Turbulent Flows
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Navier-Stokes equation solutions
  • Advanced biosensing and bioanalysis techniques
  • Platelet Disorders and Treatments
  • Electrohydrodynamics and Fluid Dynamics
  • Microfluidic and Capillary Electrophoresis Applications
  • Microfluidic and Bio-sensing Technologies
  • Advanced Proteomics Techniques and Applications
  • Polymer Surface Interaction Studies
  • Advanced Chemical Sensor Technologies
  • Computational Physics and Python Applications
  • Nanomaterials and Printing Technologies
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Polyomavirus and related diseases
  • Approximation Theory and Sequence Spaces
  • Social Representations and Identity
  • Quantum chaos and dynamical systems
  • Surface Modification and Superhydrophobicity
  • Sport Psychology and Performance
  • Plant Water Relations and Carbon Dynamics
  • Blood disorders and treatments
  • Advanced Drug Delivery Systems
  • Carbon Nanotubes in Composites
  • Blood properties and coagulation

Centre Hospitalier Sud Francilien
2022-2025

CEA Paris-Saclay
2023-2024

Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2009-2024

Université Paris-Saclay
2021-2024

Centre National de la Recherche Scientifique
2010-2023

Institut Rayonnement-Matière de Saclay
2023

CEA Grenoble
2009-2021

Assistance Publique – Hôpitaux de Paris
2021

CEA LETI
2009-2021

Université Grenoble Alpes
2014-2021

Background: Sickle cell disease (SCD) predisposes children to bacterial infections, particularly invasive pneumococcal disease. Pneumococcal immunization associated with antibiotic prophylaxis reduced the incidence of in these patients. However, risk remains higher than general population. Our main objective was describe features meningitis and estimate case-fatality rate SCD. The secondary assess serotype distribution resistance patterns proportion cases related vaccine failure. Methods:...

10.1097/inf.0000000000004755 article EN The Pediatric Infectious Disease Journal 2025-03-07

The three-dimensional reversible Navier-Stokes (RNS) equations are a modification of the dissipative (NS) equations, first introduced by Gallavotti [Phys. Lett. A 223, 91 (1996)0375-960110.1016/S0375-9601(96)00729-3], in which energy or enstrophy is kept constant adjusting viscosity over time. Spectral direct numerical simulations this model were performed Shukla et al. Rev. E 100, 043104 (2019)2470-004510.1103/PhysRevE.100.043104] and Margazoglou 105, 065110...

10.1103/physreve.107.065106 article EN Physical review. E 2023-06-26

DNA is under continuous assault by environmental and endogenous reactive oxygen alkylating species, inducing the formation of mutagenic, toxic genome destabilizing nucleobase lesions. Due to implications such genetic alterations in cell death, aging, inflammation, neurodegenerative diseases cancer, many efforts have been devoted developing assays that aim at analyzing repair activities from purified enzymes or extracts. The present work deals with conception application a new, miniaturized...

10.1039/c6an01165a article EN The Analyst 2016-01-01

We discuss how the projection of geophysical equations motion onto an exponential grid allows determination realistic values parameters at a moderate cost. This us to perform many simulations over wide range parameters, thereby leading general scaling laws transport efficiency that can then be used parametrize turbulent in climate models for Earth or other planets. illustrate this process using equation describing heat dry atmosphere obtain onset convection as function rotation. confirm...

10.3390/atmos14111690 article EN cc-by Atmosphere 2023-11-15

Abstract In 1981, Frisch and Morf (1981 Phys. Rev. A 23 2673–705) postulated the existence of complex singularities in solutions Navier–Stokes equations. Present progress on this conjecture is hindered by computational burden involved simulations Euler equations or at high Reynolds numbers. We investigate case fluid dynamics log-lattices, where logarithmic concerning ordinary simulations. analyze properties potential both 1D 3D models for lattices different spacings. Dominant are tracked...

10.1088/1361-6544/ad7661 article EN Nonlinearity 2024-09-17

PyLogGrid is a framework for performing and analyzing log-lattice simulations, as introduced by Martins (2019).

10.21105/joss.06439 article EN cc-by The Journal of Open Source Software 2024-12-31

In 1981, Frisch and Morf [1] postulated the existence of complex singularities in solutions Navier-Stokes equations. Present progress on this conjecture is hindered by computational burden involved simulations Euler equations or at high Reynolds numbers. We investigate case fluid dynamics log-lattices, where logarithmic concerning ordinary simulations. analyze properties potential both 1D 3D models for lattices different spacings. Dominant are tracked using singularity strip method to obtain...

10.48550/arxiv.2312.01702 preprint EN other-oa arXiv (Cornell University) 2023-01-01

Flow focusing devices (FFDs), with dimensions smaller than 100 mum have recently been used for cell encapsulation. However, encapsulation of larger clusters cells, like islets Langerhans, is considerable interest. Producing capsules requires FFDs. We focus here on the geometrical scaling-up between a small FFD (50 mum) and one (100 mum, 200 1 mm). determine driving pressure conditions to obtain droplet regime at any size FFD. A similar behavior device experimentally obtained by scaling ratio...

10.1109/sensor.2009.5285655 article EN TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference 2009-06-01
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