A5027945556- Circular RNAs in diseases
- Osteoarthritis Treatment and Mechanisms
- Electrospun Nanofibers in Biomedical Applications
- Cancer-related molecular mechanisms research
- Periodontal Regeneration and Treatments
- Liver Disease Diagnosis and Treatment
- Hydrogels: synthesis, properties, applications
- Tissue Engineering and Regenerative Medicine
- Bone Tissue Engineering Materials
- Pain Mechanisms and Treatments
- 3D Printing in Biomedical Research
- Cell death mechanisms and regulation
- RNA modifications and cancer
- Ferroptosis and cancer prognosis
- Mesenchymal stem cell research
- RNA Interference and Gene Delivery
- Silk-based biomaterials and applications
- Collagen: Extraction and Characterization
- MicroRNA in disease regulation
- Sexual function and dysfunction studies
Qingdao University
2019-2024
Affiliated Hospital of Qingdao University
2019-2024
Hydrogel scaffold is a popular cell delivery vehicle in tissue engineering and regenerative medicine due to its capability encapsulate cells as well modifiable properties. However, the inherent submicron- or nano-sized polymer networks of conventional hydrogel will produce spatial constraints on cellular activities encapsulated cells. In this study, we endeavor develop an innovative encapsulatable cryogel (CECG) platform with interconnected macro-pores, by combining cryopreservation...
Abstract Background The development of neuropathic pain (NP) is one the reasons why difficult to treat, and microglial activation plays an important role in NP. Recently, platelet-rich plasma (PRP) has emerged as a novel therapeutic method for knee osteoarthritis (KOA). However, it’s unclarified whether PRP analgesic effects on NP induced by KOA underlying mechanisms unknown. Purpose To observe explore potential alleviating Methods was male rats with intra-articular injections monosodium...
Abstract The macro-porous hydrogel scaffolds can not only enhance the proliferation of laden chondrocytes but also favor deposition hyaline cartilaginous extracellular matrix, however, underlying molecular mechanism is still unclear. Herein, global gene expression human cartilage (HCCs) encapsulated in traditional (Gel) constructs and micro-cavitary gel (MCG) are investigated by using high-throughput RNA sequencing (RNA-seq). differentially expressed genes (DEGs) between HCCs cultured Gel...