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Vivian Yan

ORCID: 0009-0009-0397-623X
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About
Contact & Profiles
A5099847913
Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • Immunotherapy and Immune Responses
  • Immune responses and vaccinations
  • Immune Cell Function and Interaction
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • COVID-19 Clinical Research Studies

Icahn School of Medicine at Mount Sinai
 2024

 Outcome of SARS-CoV-2 reinfection depends on genetic background in female mice
OPENALEX - Publications 
Gagandeep Singh Juan García-Bernalt Diego Prajakta Warang Seok‐Chan Park Lauren A. Chang and 11 more Moataz Noureddine Gabriel Laghlali Yonina Bykov M Prellberg Vivian Yan Sarabjot Singh Lars Pache Sara Cuadrado‐Castano Brett T. Webb Adolfo García‐Sastre Michael Schotsaert

Antigenically distinct SARS-CoV-2 variants increase the reinfection risk for vaccinated and previously exposed population due to antibody neutralization escape. COVID-19 severity depends on many variables, including host immune responses, which differ depending genetic predisposition. To address this, we perform profiling of female mice with different backgrounds –transgenic K18-hACE2 wild-type 129S1– infected severe B.1.351, 30 days after exposure milder BA.1 or H1N1. Prior infection...

10.1038/s41467-024-54334-7 article EN cc-by-nc-nd Nature Communications 2024-11-23
 Enhanced mucosal antibody- and T-cell responses against SARS-CoV-2 after heterologous intramuscular mRNA prime/intranasal protein boost vaccination with a combination adjuvant.
OPENALEX - Publications 
Gabriel Laghlali Matthew Wiest Dilara Karadag Prajakta Warang Jessica J. O’Konek and 9 more Lauren A. Chang Seok‐Chan Park Vivian Yan Mohammad Farazuddin Katarzyna Janczak Adolfo García‐Sastre James R. Baker Pamela T. Wong Michael Schotsaert

10.1016/j.ymthe.2024.10.016 article EN cc-by-nc-nd Molecular Therapy 2024-10-01
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