A5101886392- Atrial Fibrillation Management and Outcomes
- Heart Failure Treatment and Management
- Cardiac Fibrosis and Remodeling
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- Neuropeptides and Animal Physiology
- Biochemical Acid Research Studies
- Cardiac Imaging and Diagnostics
- Cardiac pacing and defibrillation studies
- Alcohol Consumption and Health Effects
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac tumors and thrombi
- Alcoholism and Thiamine Deficiency
Affiliated Hospital of Jining Medical University
2011-2023
Harbin Medical University
2008
Renin-angiotensin-aldosterone system has been demonstrated to be associated with both congestive heart failure (CHF) and atrial fibrillation (AF). This study investigated the effects of spironolactone, a kind aldosterone antagonist, on electrical remodeling fibrosis in CHF dogs induced by chronic rapid ventricular pacing.Twenty one were randomly divided into sham-operated group, control spironolactone group. In group paced at 220 beats per minute for 6 weeks. Additionally, 15 mg x kg(-1)...
LCZ696, an angiotensin receptor–neprilysin inhibitor (ARNi), is reported to play a cardioprotective role after acute myocardial infarction (AMI). Angiotensin-converting enzyme inhibitors(ACEIs) have similar roles. However, it unclear whether the combination of two drugs has better protective effect. The purpose this study was investigate effect therapy AMI. Male C57BL/6 J mice subjected ligation left anterior descending artery were treated for 4 weeks with ACEI(benazepril), or...
Chronic alcohol intake contributes to high mortality rates due ethanol-induced cardiac hypertrophy and contractile dysfunction, which are accompanied by increased oxidative stress disrupted mitophagy. Alpha-lipoic acid (α-LA), a well-known antioxidant, has been shown protect against inflammation. However, little is known about its role mechanism in the treatment of alcoholic cardiomyopathy. Here, we evaluated α-LA alcohol-induced damage feeding mice 4.8% (v/v) diet with or without for 6 w....
Objective To discuss the feasibility and accuracy of left atrial appendage (LAA) ejection fraction by real-time 3 dimensional imaging (3D-EF), tissue velocity LAA wall Doppler (TDI) via transesophageal echocardiography (TEE) in assessing functions. Methods A total number 76 patients with fibrillation (AF) were included study consecutively underwent TEE for investigations. 3D-EF, fractional area change 2 (2D-FAC), peak emptying (PEV), TDI at mid-portion lateral (TDI-L), septal (TDI-S)...