A5101852882- Plant Molecular Biology Research
- Biological and pharmacological studies of plants
- GABA and Rice Research
- Pancreatitis Pathology and Treatment
- Sarcoma Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Bone Tumor Diagnosis and Treatments
- Neuropeptides and Animal Physiology
- Contact Dermatitis and Allergies
- Allergic Rhinitis and Sensitization
- Phagocytosis and Immune Regulation
- RNA modifications and cancer
- Neuroendocrine Tumor Research Advances
- DNA Repair Mechanisms
- Renal cell carcinoma treatment
- Gastric Cancer Management and Outcomes
- Dermatology and Skin Diseases
- Pharmacological Effects of Natural Compounds
- Cancer-related Molecular Pathways
- Helicobacter pylori-related gastroenterology studies
- Vascular Tumors and Angiosarcomas
- Bone health and treatments
- Barrier Structure and Function Studies
- Immune Cell Function and Interaction
- Cancer Cells and Metastasis
Chengdu University
2023-2025
Liaoning Provincial People's Hospital
2025
China Medical University
2025
Manchester Metropolitan University
2025
Wuhan University
2023-2024
Shaoxing Second Hospital
2024
Nanjing General Hospital of Nanjing Military Command
2006-2024
Zhongnan Hospital of Wuhan University
2023-2024
Jinling Institute of Technology
2018-2024
Tianjin University
2023
<i>Objectives:</i> Resistance to chemotherapy is a major cause of treatment failure and poor prognosis in pancreatic cancer. Inasmuch as most effects chemotherapeutic agents are mediated via the activation apoptosis, cytotoxic gemcitabine 5-fluorouracil (FU) correlation with apoptosis-regulating genes cancer cell lines were analyzed. <i>Methods:</i> The 5-FU AsPC-1, Capan-1, Mia-PaCa-2 T3M4 assessed by growth assays, mRNA expression levels pro-apoptotic anti-apoptotic...
Rhodiola crenulata (Hook.f. & Thomson) H.Ohba, a member of the Crassulaceae family, is traditional Chinese medicine recognized as original source Rhodiolae Crenulatae Radix et Rhizoma in 2020 edition China Pharmacopoeia. It has been widely used both Asia and Europe to enhance stress resistance reduce fatigue. However, classification species can lead confusion, raising safety concerns herbal market. The cleaved amplified polymorphic sequence (CAPS) RT-PCR was identify single nucleotide...
Introduction ZO-1 is a tight junction membrane protein that plays critical role in cell–cell interaction, proliferation, and differentiation. Aim To localize evaluate the expression of normal human pancreas, pancreatic ductal adenocarcinoma (PDAC), chronic pancreatitis (CP). Methodology Results Northern Western blot analysis revealed all six tested cancer cell lines. Expression mRNA was increased sixfold PDAC samples comparison with (p = 0.04). Confocal microscopy presence apical...
Physical forces are prominent during tumor progression. However, it is still unclear how they impact and drive the diverse phenotypes found in cancer. Here, we apply an integrative approach to investigate of compression on melanoma cells. We bioinformatics screen for most significant compression-induced transcriptomic changes phenotypic responses. show that associated with both improvement worsening patient prognoses. Phenotypically, volumetric inhibits cell proliferation migration. It also...
Leptomeningeal disease (LMD) is a serious cancer complication associated with poor prognosis. Approximately 5%-25% of patients melanoma develop LMD. Currently, no standard treatment protocol exists and very few cases have been reported. Despite ongoing advances in new therapies, options for LMD remain limited. Herein, we report case intrathecal pembrolizumab administration patient Intrathecal was feasible safe at the doses tested. Drawing from this case, along our expertise existing evidence...
Generation and maintenance of pain in chronic pancreatitis (CP) have been shown to be partially attributable neuroimmune interactions, which involve neuropeptides such as substance P (SP). So far, expression SP receptors NK-2R, NK-3R, the SP-encoding gene preprotachykinin A (PPT-A), degradation enzyme neutral endopeptidase (NEP) their relation CP not determined.Tissue samples from patients with (n = 25) healthy donors 20) were analyzed for PPT-A, NEP using quantitative RT-PCR. protein levels...
Dendrobium officinale Kimura et Migo (D. officinale) is a well-known traditional Chinese medicine with high content polysaccharides in stems. The SWEET (Sugars Will Eventually be Exported Transporters) family novel class of sugar transporters mediating translocation among adjacent cells plants. expression patterns SWEETs and whether they are associated stress response D. remains uncovered.Here, 25 genes were screened out from genome, most which typically contained seven transmembrane domains...
This study aims to evaluate the effect of rhythm training in early coordination development and find out its role transfer specific performance young swimmers. Eighty swimmers aged eight twelve were divided randomly into a control group (CON, n = 40, M/F=17/23) or an experimental (EXP, M/F=19/21). A total 72 completed all programs tests included this 35, M/F=15/20; EXP, 37, M/F=16/21). The programme lasted 12 weeks. During period, groups participated same swimming program with participating...
This study analyzes the role of phosphatidylserine receptor (PSR) in chronic pancreatitis.In pancreatitis, destruction parenchyma comes along with infiltration lymphocytes and macrophages. The is expressed on surface macrophages crucial for recognition engulfment apoptotic cells. In present study, we investigated this its relation to apoptosis pancreatitis.The expression localization PSR were analyzed by Northern blot analysis, RT-PCR, Western analysis immunohistochemistry. Apoptosis was...
To evaluate the effect of personalized prechemotherapy education in reduction peri-chemotherapy anxiety patients with colorectal cancer.Patients admitted to Department Oncology a diagnosis stage III or IV cancer and scheduled for initial chemotherapy from January 1, 2017, June 30, 2019, were retrieved. Patients educated group completed GAD-7 form their level at admission 14 days after education, educator team which included both physician nurse staff. control only forms thereafter without...
Apatinib mesylate, a small-molecule tyrosine kinase inhibitor (TKI) of vascular endothelial growth factor receptor-2 (VEGFR-2), has been recommended as third-line class A agent for patients with advanced gastric adenocarcinoma in China since April 2018. Thus far, there is no case report on the combined use apatinib and S-1 first-line treatment option metastatic cancer (GC) based peripheral circulating tumor cell (pCTC) monitoring. We present unique which liver metastases originating from GC...
The structural and functional characteristics of cells are dependent on the specific gene expression profile. ability to study compare at cellular level will therefore provide valuable insights into cell physiology pathophysiology.Individual were isolated from frozen colon tissue sections using laser microdissection. DNA as well RNA extracted, total was reversely transcribed complementary (cDNA). Both cDNA analyzed by nested polymerase chain reaction (PCR). quality satisfactory.Single...