Hybrid hydrogen-bonded (H-bonded) frameworks built from charged components or metallotectons offer diverse guest-framework interactions for target-specific separations. We present here a study to systematically explore the coordination chemistry of monovalent halide anions, i.e., F- , Cl- Br- and I- with aim develop hybrid H-bond synthons that enable controllable construction microporous H-bonded exhibiting fine-tunable surface polarity within adaptive cavities realistic xenon/krypton...

Although cholesterol metabolism is a common pathway for the development of antitumor drugs, there are no specific targets and drugs clinical use. Here, based on our previous study sterol O-acyltransferase 1 (SOAT1) in hepatocelluar carcinoma, we sought to screen an effective targeted drug precise treatment carcinoma and, from perspective metabolism, clarify relationship between regulation tumorigenesis development.In this study, developed virtual screening integrated affinity technology...

When an electromagnetic transient occurs in a transformer, certain parts of the winding will be over stressed internally, which severe cases lead to destruction insulation. Excitation inrush current and short-circuit are main causes damage during transients, resulting or accelerating damage, presence excitation can greatly reduce service life power transformers. The process closing energizing transformer generates large inrush, when amplitude is same, greater force than current. In this...

Abstract Background The third-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) can penetrate blood–brain barrier and are effective for brain metastases (BMs). There is no consensus on the optimal sequence of local therapy (LT) EGFR-TKIs symptomatic BM patients because suffering neurological symptoms were not enrolled in most clinical trials. Methods Non-small cell lung cancer (NSCLC) with EGFR mutation (EGFRm) receiving first-line osimertinib aumolertinib...

Selectively engineering the dynamic bonds in supramolecular assemblies stabilized by cooperative weak interactions is challenging yet critical to modulate their spatial organizations and stimuli-responsive behaviors. This study presents a novel class of crystalline polyphenol hierarchically regulated interplay π–π stacking reconfigurable hydrogen (H-bonds). Oriented structural reorganization low-dimensional nanocrystals, accompanied "self-correction", could be achieved selectively H-bond...

Constructing well-organized organic frameworks with tailor-made functionalities potentially boost multi-domain applications. Hydrogen bonding (H-bonding) is a category of general and weak intermolecular interactions when compared covalent or metal-ligand coordination. Porous mainly assembled by H-bonding (named hydrogen-bonded frameworks, HOFs) are intrinsically capable decomposing regenerating, distinctive advantage to improve their processability while expanding the applicability. This...

Cryogenic trapped-ion systems (CTISs) have emerged as indispensable platforms for the advancement of quantum computation and precision measurement techniques. However, sensitivity these to vibrational noise, especially during compression expansion cycles cold head in a Gifford-McMahon cycle refrigerator (GMCR), poses significant challenge. To mitigate this, we crafted an innovative methodology characterizing low-frequency residual noise closed-cycle cryogenic systems. Our is underpinned by...

Electromagnetic interference has always been an important assessment indicator for the inspection of power intelligent Unmanned Aerial Vehicles (UAVs). Therefore, it is necessary to carry out a structure optimization study improve UAV's anti-electromagnetic capability. This paper analyses flight stability UAV at different heights under strong magnetic environment dry-type transformer, and carries structural optimisation rotary-wing design against standard non-magnetic environment. After...

When the electromagnetic transients occur in a power transformer, an inrush current is generated its winding. The not only affects performance of transformer windings, but also lifetime transformer. Many factors affect current, most influential ones among which are closing phase angle and residual flux. In this paper, dry-type simulation model built to analyze influence on windings during no-load reclosing conditions. Firstly, was operation under different fluxes. Secondly, field-circuit...

In this paper, the hydrostatic effect of rectangle micro-texture (RMT) on liquid-lubricated mechanical seal is numerically investigated. A model with RMT developed finite element method (FEM). The and circular (CMT) partial surface are compared analysed. Results show that optimised can greatly improve opening force seal. orientation factor g = 1/3 about 18% larger than CMT in typical case. Furthermore, influence force, leakage efficiency parameter design discussed under different operating...

Developing advanced sorbents for selective carbon dioxide (CO2) sequestration with minimal energy consumption remains a pivotal challenge. This study presents novel strategy through transforming 3D bulk zirconium-porphyrin frameworks into the corresponding 2D nanosheet-assembled superstructures enhanced CO2 capture. The hierarchical well-organized nanosheet architectures exhibit significantly increased specific surface area from 600 m2/g to 2400 while providing kinetic benefits gas...

Abstract Metal‐organic frameworks bearing coordinatively unsaturated metal sites (CUSs) exhibit distinctive interactions toward guest molecules, thereby presenting intriguing properties in photocatalytic applications. Herein, an adaptable strategy is established to create 2D metal‐porphyrin while engineering the CUSs based on use of bivalent nodes (Zn 2+ , Co Cu Ni Cd ) and Zr‐O clusters. The strong surface‐coordination effect reduces energy barriers activate acrylate monomers adsorbed...

The thermal washing of oily sludge using sodium persulfate (SD) assisted by lignosulfonate surfactant has been demonstrated to be an effective method for remediation. To further explore the underlying mechanisms this process, a systematic study was conducted simulating systems consisting saturated hydrocarbons (SaH), aromatics (ArH), resins (Res), and asphaltenes (Asp). effects reaction conditions, such as pH, alkyl (LSA) concentration, SD temperature, were analyzed. Furthermore, oxidative...

Feed drives are one of the most important parts machine tools. Their static and dynamic behavior strongly influences positioning accuracy their speed determines productivity. The control parameters play a decisive role concerning performance mechatronic system for analysis, sufficient model feed drive is necessary. This paper demonstrates structure using object-oriented modeling in MATLAB/ SIMSCAPETM. validated by comparing simulation with measured results example precision machining center....

Mechanical seal face texturing has the advantage of improving mechanical performance, such as opening force, reducing friction coefficient and minimizing wear so on. In this paper, face, composed sintered silicon carbon(S-SiC), is textured by acoustic-optic Q-switched pulsed Nd:YAG laser in multi-mode. The micro-dimples are produced profiles measured scanning electron microscopy (SEM) 3D white light interference surface morphology apparatus. Results show that it focus plane maximal depth...