Xuemei Xu

ORCID: 0009-0009-3480-1424
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Research Areas
  • Lung Cancer Treatments and Mutations
  • Genetics, Aging, and Longevity in Model Organisms
  • Radical Photochemical Reactions
  • Analytical Chemistry and Chromatography
  • Antibiotic Use and Resistance
  • Bacterial biofilms and quorum sensing
  • Periodontal Regeneration and Treatments
  • Molecular Sensors and Ion Detection
  • Peptidase Inhibition and Analysis
  • Nutritional Studies and Diet
  • Synthesis and properties of polymers
  • Heavy Metal Exposure and Toxicity
  • Vanadium and Halogenation Chemistry
  • HER2/EGFR in Cancer Research
  • Catalytic C–H Functionalization Methods
  • Cancer Mechanisms and Therapy
  • Geochemistry and Elemental Analysis
  • Cytokine Signaling Pathways and Interactions
  • Sulfur Compounds in Biology
  • Consumer Attitudes and Food Labeling
  • Adsorption, diffusion, and thermodynamic properties of materials
  • Infections and bacterial resistance
  • Chemical Synthesis and Reactions
  • Electrocatalysts for Energy Conversion
  • Antimicrobial Resistance in Staphylococcus

Wuhan Institute of Technology
2023-2025

Guangxi Medical University
2021-2024

Southern Medical University
2024

Nanfang Hospital
2024

Wenzhou Hospital of Traditional Chinese Medicine
2023-2024

Anhui University of Science and Technology
2021

Zigong First People's Hospital
2019

Huazhong University of Science and Technology
2014

82th Hospital of Pla
2011

University of South China
2010

In this work, a tetraphenylethene-coumarin hybrid fluorophore (TPE-Cou) that contains Schiff base form is designed and synthesized. A combination of plentiful optical properties chemical reactivity towards thiols allows TPE-Cou to work as an excellent turn-on probe with wide linear range, revealing the great potential dye quantitative fluorescence indicator. By means NMR spectrum analyses, mechanistic picture at molecular level has been drawn illustrate how works bio-thiol-sensitive...

10.1039/c4nr04593a article EN Nanoscale 2014-10-30

Electrochemical oxidative cross-dehydrogenative-coupling (CDC) is an ideal strategy to develop C3-alkoxylation of imidazo[1,2-a]pyridine but still remains a challenge owing limitation by the use alkyl alcohols and carboxylic acids....

10.1039/d4ob02073a article EN Organic & Biomolecular Chemistry 2025-01-01

Sugar-sweetened beverage (SSB) consumption has shown associations with cognitive function in preschool children, but effects of other ultraprocessed foods are rarely discussed China. This study aimed to investigate the relationship between food and among children China.A total 325 aged 4-7 years were included from Guangxi Zhuang Birth Cohort Autonomous Region, Face-to-face interviews parents using Food Frequency Questionnaire (FFQ) was conducted status seven (i.e., chocolate, biscuits,...

10.3389/fnut.2023.1272126 article EN cc-by Frontiers in Nutrition 2023-10-10

Asymmetric electrosynthesis is an innovative approach that combines electrochemistry with asymmetric catalysis, enabling the selective synthesis of chiral molecules. Advancements in green chemistry have positioned as a powerful...

10.1039/d4gc05316h article EN Green Chemistry 2024-01-01

Mesoporous silica nanoparticles (MSNs), as novel nanocarriers for drug delivery in cancer treatment, have attracted widespread concern because of their rich pore structure, large capacity, ease modification, and biocompatibility. However, the limitation nontargeting low uptake efficiency hindered further application. Considering overexpression transferrin receptor (TfR) on most cell membranes, herein, we propose a strategy to effectively enhance cellular internalization MSNs by arming them...

10.1021/acsomega.3c06562 article EN cc-by-nc-nd ACS Omega 2023-12-12

Bio-activity conservation of biomolecules after immobilizing in nanomaterials has been a tough challenge, especially biomedical applications.

10.1039/d2nj03324k article EN New Journal of Chemistry 2023-01-01

<title>Abstract</title> <bold>Background:</bold> Based on the spatial distribution of immune cells, tumors are classified into three immunophenotypes: immune-inflamed, immune-excluded and immune-desert, among which immune-inflamed phenotype exhibits favorable prognosis, high immunotherapy response rate, abundant CD8+ T cells infiltration. However, there is no existing study elucidating distinctive features under background in colorectal cancer (CRC). <bold>Methods: </bold>Bulk RNA sequencing...

10.21203/rs.3.rs-4791492/v1 preprint EN cc-by Research Square (Research Square) 2024-08-21

Abstract Objective To investigate the association between rare earth elements (REEs) and metabolic syndrome (MetS). Methods We used a cross-sectional design based on baseline data of Prospective Cohort Study Chronic Diseases in Ethnic Minority Natural Population Guangxi China. Logistic regression BKMR models were employed to evaluate REEs risk MetS. Results Although not significantly associated with MetS, certain such as La, Pr, Nd negatively abdominal obesity, while Ce, Nd, Dy positively...

10.1097/jom.0000000000003217 article EN Journal of Occupational and Environmental Medicine 2024-09-04

To estimate whether adjuvant radiotherapy is necessary for patients with stage IA1-IIA1 cervical cancer after laparoscopic hysterectomy, 221 were retrospectively analyzed. Sixty-two of them treated hysterectomy and (group A), 115 underwent open surgery B) 44 received alone C). Results showed that the 3-year local recurrence-free survival (LRFS) rates group A, B C 98.4%, 97.4% 86.4%, respectively. The LRFS A surpassed (A vs . B, p=0.634; C, p=0.011; p=0.006). inter-group differences overall...

10.3389/fonc.2021.690777 article EN cc-by Frontiers in Oncology 2021-07-26

Objective To investigate the application of peroneal artery chain perforator flap in repairing skin and soft tissue defects ankle lower leg corresponding clinical effect.Methods From 2005 to 2010,19 cases tissue'defects were treated by using flaps.The sites branches detected Doppler flowmeter before operation.Supplied form terminal artery,the cutaneous fulcrum straightly nearest wound was selected as rotation point design flap,with area ranging from 25 cm × 8 16 6 cm.Results The follow-up...

10.3760/cma.j.issn.1001-8050.2011.12.013 article EN 2011-12-15

Carbapenem antibiotics are a pivotal solution for severe infections, particularly in hospital settings. The emergence of carbapenem-resistant bacteria owing to the irrational and extensive use carbapenems underscores need meticulous management rational use. Clinical pharmacists, with their specialized training knowledge, play substantial role ensuring judicious carbapenem. This study aimed elucidate patterns carbapenem shed light on integral played by clinical pharmacists managing promoting...

10.12998/wjcc.v11.i30.7302 article EN World Journal of Clinical Cases 2023-10-24

Objective To retrospectively analyze the distribution of non-fermentative bacteria causing bloodstream infection in hospitalized patients Sichuan Province and their drug susceptibility to common antibiotics for better understanding epidemiological characteristics. Methods From January 1, 2015 December 31, 2017, all isolated from with nine hospitals were collected. Species resistance test results analyzed. Results A total 6 291 strains pathogenic isolated, including 3 674...

10.3760/cma.j.issn.0254-5101.2019.09.010 article EN 2019-09-30

: A novel, mild and efficient protocol to synthesize dibrominated propanamides has been developed. The presented methodology provides several merits, such as easy-to-handle stable brominated substrate, catalyst-free, additive free facile experimental operation. preliminary mechanism study indicated that a radical pathway might be involved in the reaction.

10.2174/1570178618666210920114503 article EN Letters in Organic Chemistry 2021-09-21
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