A5026812110- Corneal Surgery and Treatments
- Corneal surgery and disorders
- Intraocular Surgery and Lenses
- Connexins and lens biology
- Ocular Surface and Contact Lens
- Ecology and Conservation Studies
- Developmental Biology and Gene Regulation
- Planarian Biology and Electrostimulation
Saarland University
2023-2025
Semmelweis University
2023-2024
Congenital aniridia is increasingly recognized as part of a complex syndrome with numerous ocular developmental anomalies and non-ocular systemic manifestations. This requires comprehensive care treatment affected patients. Our purpose was to analyze diseases in patients congenital within the Homburg Aniridia Registry. retrospective, monocentric study included who underwent ophthalmic examination at Saarland University Medical Center beginning June 2003. Age, gender, genetic test results,...
Purpose During life up to 70% of aniridia subjects develop aniridia-associated keratopathy (AAK). AAK is characterized by limbal stem cell insufficiency, impaired corneal epithelial differentiation and abnormal adhesion, which leads centripetal spreading vascularization, conjunctivalization, thickening the cornea. Our aim was examine subbasal nerve plexus central stromal microstructure in with congenital aniridia, using vivo confocal laser scanning microscopy CLSM.
Abstract Purpose Congenital aniridia is a severe malformation of almost all eye segments. In addition, endocrinological, metabolic, and central nervous systems diseases may be present. order to develop better treatment options for this rare disease, an center must established. The purpose work summarize ophthalmic findings subjects examined at the Department Ophthalmology, Saarland University Medical Center in Homburg. Methods Our retrospective single-center study included patients who...
Congenital aniridia is a severe malformation of almost all eye segments. Aniridia-associated keratopathy (AAK) and secondary glaucoma, which occur in more than 50% affected individuals, are typically progressive pose high risk blindness for patients with congenital aniridia. Our aim was to investigate the effect glaucoma treatment on AAK Homburg Aniridia Center.Our retrospective monocentric study included who underwent comprehensive ophthalmological examination at Center between June 2003...
The potential risks and benefits of cataract surgery, in context congenital aniridia (CA), are not widely understood, yet. Our purpose was to investigate the effect lens properties on visual acuity (VA), aniridia-associated keratopathy (AAK) stage presence glaucoma at Homburg Aniridia Center.
Bevezetés: A congenitalis aniridia ritka betegség, melynek fő jellemzője a szivárványhártya teljes vagy részleges hiánya, azonban szem összes struktúrájában jelen lehetnek elváltozások. Célkitűzés: Társuló szembetegségek előfordulásának meghatározása aniridiában, egy magyarországi centrum betegeinek vizsgálatával. Betegek és módszerek: Munkánkba Semmelweis Egyetem Szemészeti Klinikáján 2005. október 2022. május között diagnózisával vizsgált betegeket válogattunk be. betegek...
In PAX6 syndrome, it is still not clear, whether prenatally, parallel to the iris tissue developmental anomaly, there neural ectodermal, crest, or mesodermal cell deposition at corneal endothelium, affecting endothelial structure and function. addition, because of postnatal inflammation commonly appearing secondary glaucoma, progressive changes are expected. Our purpose was study endothelium in subjects with aniridia, using vivo confocal laser scanning microscopy.
Purpose : Congenital aniridia is a rare disease, with global prevalence of 1 in 40 000 to 100 000. During life up 70% sufferers develop aniridia‐associated keratopathy (AAK) limbal stem cell insufficiency, impaired corneal epithelial differentiation, abnormal adhesion and wound healing. AAK characterized by centripetal spreading vascularization, conjunctivalization, thickening the cornea. We examined sub‐basal nerve plexus central stromal microstructure subjects congenital aniridia, using...
In congenital aniridia, there is malformation of almost all eye segments. addition, endocrinologic, metabolic and central nervous systems diseases may be present. The most common ophthalmic signs in aniridia are AAK, iris malformation, cataract macular hypoplasia. Between 556 eyes 286 subjects (20.1 ± 20.1 years; 45.5% males), was nystagmus 518 (93.7%) eyes, strabismus 327 (58.8%) eyes. There with atypical coloboma 34 (6.1%), more than 6 clock hours remnants 61 (10.9%), less 96 (17.2%),...
Abstract Introduction Congenital aniridia is a rare panocular disorder that associated with varying degrees of impairment visual acuity. The COST Action (CA18116) developed survey (aniridia-net.eu) to assess patient-reported experiences congenital and its impacts on vision daily life. Here, we correlate the responses German patients clinical ophthalmology data acquired at Homburger Aniridia Center. Patients Methods completed German-language version 20-point ANIRIDIA-NET survey. included...
Bevezetés: A congenitalis aniridia ritka panocularis betegség, amelyben a szem csaknem minden struktúrája érintett, és betegek többségének jelentősen csökkent látóélessége. szemészeti jelei lehetnek az aniridiához társult keratopathia, másodlagos zöld hályog, szürke macula- opticus-hypoplasia, nystagmus. Noha keratopathia kifejezés régóta elterjedt irodalomban, sokféle stádiumbeosztási javaslata került már leírásra. Célkitűzés: Az egyes stádiumainak vizsgálata irodalomban elérhető...
Bevezetés: Az aniridia ritka, veleszületett panocularis betegség, mely a látóélesség különböző mértékű csökkenésével jár. Célkitűzés: Veleszületett aniridiás betegek látáskárosodásukkal kapcsolatos tapasztalatainak felmérése Magyarországon egy, az ANIRIDIA-NET által készített kérdőív segítségével. Betegek és módszer: A vizsgálatba Semmelweis Egyetem Szemészeti Klinikáján 2005. október 2022. május között congenitalis diagnózisával vizsgált vagy kezelt betegeket válogattuk be. 20 pontból álló...