A5091993791- Lymphoma Diagnosis and Treatment
- Ovarian function and disorders
- Reproductive Biology and Fertility
- CAR-T cell therapy research
- Gynecological conditions and treatments
- Growth Hormone and Insulin-like Growth Factors
- Plant Water Relations and Carbon Dynamics
- Nail Diseases and Treatments
- Vascular Tumors and Angiosarcomas
- Reproductive Health and Technologies
- Plant responses to elevated CO2
- Ovarian cancer diagnosis and treatment
- Bone health and osteoporosis research
- Genetics and Neurodevelopmental Disorders
- Bone Metabolism and Diseases
- Metabolomics and Mass Spectrometry Studies
- Remote Sensing in Agriculture
- Immune Cell Function and Interaction
- Reproductive tract infections research
- Autoimmune and Inflammatory Disorders Research
- T-cell and Retrovirus Studies
- DNA Repair Mechanisms
- Bee Products Chemical Analysis
- Viral Infectious Diseases and Gene Expression in Insects
- Cardiac tumors and thrombi
First Affiliated Hospital of Zhengzhou University
2023-2025
Beijing University of Chinese Medicine
2024-2025
Changchun University of Chinese Medicine
2025
JiangSu Armed Police General Hospital
2018
Guangzhou Medical University
2018
Purpose: T-cell lymphoblastic lymphoma (T-LBL) has a poor response to traditional chemotherapy regimens, and is prone relapse after treatment. Effective drugs are lacking for relapsed refractory (RR) T-LBL patients, highlighting the need novel treatments. Selinexor decitabine have good effects on variety of hematolymphatic diseases solid tumors, but how effective they in treating not been reported. In this study, we first investigated efficacy mechanism selinexor combined with treatment T-...
6515 Background: Patients with relapsed/refractory T-lymphoblastic leukemia/lymphoma (r/r T-ALL/LBL) are clinically manifested by rapid disease progression, poor prognosis and lack of therapeutic options. There is an urgent need to develop other effective modalities. Apart from its expression in normal T NK cells no tissue cells, CD7 highly expressed T-ALL/LBL cells. Therefore, considered a potential target for the development CAR-T therapy T-ALL/LBL. The challenge, however, avoid fratricide...
Objective To analyze the clinical prognostic factors and treatments for angioimmunoblastic T-cell lymphoma (AITL) develop a novel model specifically AITL. Method We retrospectively analyzed 231 patients with AITL from First Affiliated Hospital of Zhengzhou University. Patients were enrolled between January 2014 July 2023. The primary end points overall survival (OS) progression-free (PFS). Result patients’ median age was 63 years, 88.3% at an advanced stage (III/IV). majority (47.6%)...
Extra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important role in reproduction. To study the treatment effect of Grin (a novel hGHRH homodimer), infertility models 85 male Chinese hamsters were established by intraperitoneally injecting 20 mg/kg cyclophosphamide once a week for 5 weeks and with or human menopausal gonadotropin (hMG) as positive control was evaluated performing 3-week mating experiment. 2-8 200 U/kg hMG showed similar different pathological...
Abstract Objective To analyze the current treatment status and prognostic regression of rare disease: chronic NK cell lymphoproliferative disorder (CLPD-NK). Methods We retrospectively analyzed clinical features, prognosis 18 patients with CLPD-NK who were treated at First Affiliated Hospital Zhengzhou University between September 2016 2022. Results Eighteen included: three chemotherapy, five underwent immune-related therapy, one patient was glucocorticoids alone, administered granulocyte...