- Mobile Health and mHealth Applications
- Blood Pressure and Hypertension Studies
- Cancer Immunotherapy and Biomarkers
- Digital Mental Health Interventions
- Plant Pathogens and Resistance
- Lung Cancer Research Studies
- Cannabis and Cannabinoid Research
- Plant-Microbe Interactions and Immunity
- Polyamine Metabolism and Applications
- Circular RNAs in diseases
- Renal and related cancers
- Robotics and Sensor-Based Localization
- Advanced Image and Video Retrieval Techniques
- Single-cell and spatial transcriptomics
- Antimicrobial Peptides and Activities
- Immune cells in cancer
- Cancer-related molecular mechanisms research
- Potato Plant Research
- RNA modifications and cancer
- Ferroptosis and cancer prognosis
- Pancreatic and Hepatic Oncology Research
- Pluripotent Stem Cells Research
- Advanced Vision and Imaging
- Behavioral Health and Interventions
Chinese Academy of Sciences
2023-2024
Center for Excellence in Brain Science and Intelligence Technology
2023-2024
Southern Medical University
2023-2024
Nanfang Hospital
2023-2024
Hefei Institutes of Physical Science
2023
Institute of Intelligent Machines
2023
Columbia College
2022
Sichuan Normal University
2022
University of Science and Technology of China
2022
Radiation-induced hepatic stellate cell (HSC) activation promotes radiation-induced liver fibrosis (RILF), a complication for hepatocellular carcinoma (HCC) radiotherapy. The demethylase alpha-ketoglutarate-dependent dioxygenase alkB homolog 5 (ALKBH5) decreases N6-methyladenylate methylation (m6 A) modification of RNA, while its role in regulating RILF pathogenesis and HCC radiosensitivity remains unknown.Methylated RNA immunoprecipitation sequencing (MeRIP-seq) RNA-sequencing (RNA-seq)...
Abstract Bone metastasis is of common occurrence in renal cell carcinoma with poor prognosis, but no optimal treatment approach has been established for bone metastatic carcinoma. To explore the potential therapeutic targets carcinoma, we profile single transcriptomes 6 primary and 9 We also include scRNA-seq data early-stage late-stage normal kidneys healthy marrow samples study to better understand niche. The molecular properties dynamic changes major lineages environment are...
Late blight is one of the main biological stresses limiting potato yield; however, biochemical mechanisms underlying infection process Phytophthora infestans remain unrevealed. In this study, late blight-resistant cultivar Ziyun No.1 (R) and susceptible Favorita (S) were inoculated with P. infestans. Untargeted metabolomics was used to study changes metabolites in compatible incompatible interactions two cultivars pathogen at 0, 48, 96 h postinoculation (hpi). A total 819 identified,...
Hypertension is the most prevalent chronic condition and a significant risk factor for cardiovascular kidney diseases. The efficacy of health behavioral interventions in blood pressure (BP) control has been demonstrated by large expanding body literature, with "adherence" playing crucial role. WeChat common social communication mobile app China, it shown to be an acceptable delivery platform delivering interventions. WeChat-based digital intervention program (WHBDIP) showed high feasibility...
<title>Abstract</title> Disturbances in tumor cell metabolism reshape the microenvironment (TME) and impair antitumor immunity, but implicit mechanisms remain elusive. Here, we found that spermine synthase (SMS) was significantly upregulated cells, which correlated positively with immunosuppressive microenvironments predicted poor survival hepatocellular carcinoma (HCC) patients. Via “subcutaneous” “orthotopic” HCC syngeneic mouse models a series of <italic>in vitro</italic> coculture...
<sec> <title>BACKGROUND</title> Hypertension is the most prevalent chronic condition and a significant risk factor for cardiovascular kidney diseases. The efficacy of health behavioral interventions in blood pressure (BP) control has been demonstrated by large expanding body literature, with “adherence” playing crucial role. WeChat common social communication mobile app China, it shown to be an acceptable delivery platform delivering interventions. WeChat-based digital intervention program...
Immune checkpoint inhibitors (ICIs) are a new way of immunotherapy, not simply refers to the improvement immunity body, but by improving immune microenvironment around tumor, thereby activating cell activity in vivo achieve anti-tumor purposes. Now, CTLA‐4 and PD‐1 or PD‐L1 monoclonal antibody mainly developed relatively successfully for checkpoints, addition other checkpoints that have been discovered clinically tested. However, while successively, some vague problems still need be solved,...