A5092596846- Bioinformatics and Genomic Networks
- Drug-Induced Hepatotoxicity and Protection
- Curcumin's Biomedical Applications
- Ubiquitin and proteasome pathways
- Cannabis and Cannabinoid Research
- Nanoplatforms for cancer theranostics
- Tryptophan and brain disorders
- Circular RNAs in diseases
- Viral Infectious Diseases and Gene Expression in Insects
- Ion Transport and Channel Regulation
- Liver Disease Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Pancreatic function and diabetes
- Nanoparticles: synthesis and applications
- Exercise and Physiological Responses
- Computational Drug Discovery Methods
- Emotion and Mood Recognition
- Sirtuins and Resveratrol in Medicine
- Chronic Kidney Disease and Diabetes
- Lipid metabolism and disorders
- MicroRNA in disease regulation
- Chemotherapy-induced organ toxicity mitigation
- Cell death mechanisms and regulation
- Music and Audio Processing
- Pregnancy and Medication Impact
Princess Nourah bint Abdulrahman University
2023-2025
Technical University of Munich
2025
The agricultural fumigant pesticide aluminum phosphide (AlP) is cardiotoxic. Water causes AlP to emit phosphine gas, a cardiac toxin that affects heart function and cardiogenic shock. poisoning's high fatality rate due cardiotoxicity. This study examines how resveratrol reduces oxidative stress, mitochondrial activity, apoptosis in human myocyte (HCM) cells. After determining the optimal doses of using MTT test, HCM cells were subjected 24-h treatment following exposure (2.36 μM). levels...
This study assessed the effects of Acacia Senegal (AS) combined with insulin on Na+/K+-ATPase (NKA) activity and mRNA expression, serum glucose, renal function, oxidative stress in a rat model diabetic nephropathy (DN). Sixty rats were equally divided into six groups: normal control, normal+AS, (DM), DM+insulin, DM+AS, DM+insulin+AS groups. Diabetes mellitus (type 1) was induced by single injection streptozotocin (65 mg/kg), AS treatments carried until culled at end week 12. Serum glucose...
Abstract Circular RNAs (circRNAs) are a new class of endogenous RNA regulating gene expression. However, the regulatory mechanisms lipid metabolism in yaks involved circRNAs remain poorly understood. The IMF plays crucial role quality yak meat, to greatly improve meat quality. In this study, fatty acid profiles were determined and sequenced. results showed that total polyunsaturated (PUFA) content adult muscle was significantly higher than calves ( p < 0.05). A 29,021 identified tissue,...
Hepatocellular carcinoma (HCC) ranks fourth in cancer-related mortality worldwide. This study aims to uncover the genes and pathways involved HCC through network pharmacology (NP) discover potential drugs via machine learning (ML)-based ligand screening. Additionally, toxicity prediction, molecular docking, dynamics (MD) simulations were conducted. NP identified key related HCC, particularly enzymes AKT1 GSK3β. Pathway analysis revealed that crucial like PI3K-AKT WNT signalling play pivotal...