A5064713698- Remote Sensing and Land Use
- Land Use and Ecosystem Services
- Environmental Changes in China
- Pancreatitis Pathology and Treatment
- Tendon Structure and Treatment
- Environmental Quality and Pollution
- Pancreatic and Hepatic Oncology Research
- Urban Transport and Accessibility
- Cancer Immunotherapy and Biomarkers
- Innovative Teaching and Learning Methods
- Pediatric Hepatobiliary Diseases and Treatments
- Experimental Learning in Engineering
- Biomedical Research and Pathophysiology
- Autophagy in Disease and Therapy
- Regional Development and Environment
- Elbow and Forearm Trauma Treatment
- Regional Economic and Spatial Analysis
- Evaluation Methods in Various Fields
- Immunotherapy and Immune Responses
- Educational Technology and Assessment
- Environmental and Agricultural Sciences
- Forest, Soil, and Plant Ecology in China
- Myofascial pain diagnosis and treatment
- Remote Sensing in Agriculture
- Immune Cell Function and Interaction
Jiangxi Maternal and Child Health Hospital
2024-2025
Zhejiang University
2023-2025
Northeast Normal University
2018-2025
University of Electronic Science and Technology of China
2018-2024
First Affiliated Hospital Zhejiang University
2023-2024
Nanchang University
2022-2024
Sichuan Provincial Hospital of Traditional Chinese Medicine
2024
Wenzhou Medical University
2024
Guangzhou Marine Geological Survey
2023
China Geological Survey
2023
Abstract Urbanization level is an important indicator of socioeconomic development, and projecting its dynamics fundamental for studies related to global climate change. This paper aims update the projections urbanization from 2015 2100 under Shared Socioeconomic Pathways by using logistic fitting model iteratively identifying reference countries. Based on historical database World Prospects, projected levels uncertainties are provided 204 countries areas every five years. The 2010–2100...
Sharing with others is an important prosocial behavior, which widely developed in early childhood. Numerous studies have demonstrated that single characteristics (routine behaviors or inter-group relations) of the recipient impact children’s sharing behavior. However, there still a lack understanding factors influence decisions children dual characteristics. In Experiment 1, 112 aged 4–6 years (Mage = 5.55, girls account for 50%) participated sticker-sharing task, and results indicated older...
β-hydroxybutyrate (β-HB) may serve as a signaling metabolite in many physiological processes beyond fuel source for tissues. However, whether and how it is involved ketone body metabolism still unknown. The present study aims to investigate the role of lysine β-hydroxybutyrylation (Kbhb) modification mediated by β-HB regulating metabolic homeostasis both vivo vitro. starvation ketosis type 1 diabetes mouse models were introduced evaluate influence on Kbhb mice. modifications OXCT1 HMGCS2,...
Severe acute pancreatitis (SAP)-induced intestinal bacterial translocation and enterogenic infection are among the leading causes of mortality in patients. However, mechanisms by which SAP disrupted barrier led to remained unclear. Therefore, we employed multi-omics analysis including microbiome, metabolome, epigenome, transcriptome, mass cytometry (CyTOF) identify potential targets, followed functional validation using transgenic mice. The integrated primarily indicated overgrowth...
Heavy metal pollution is a serious concern in the urban area of China. Understanding history crucial for setting up appropriate measures control. Herein, we report record concentrations 10 heavy metals (Fe, Mn, Cu, Zn, Ni, Cr, Cd, Pb, Co, and Sr) Pinus massoniana tree rings from Fuzhou City over past 168 years, which represents longest tree-ring chronology The studied displayed contrasting distribution patterns. Among them, Mn Sr showed strongest migration trend with peak at pith. Pb also...
Objective: PD-L1 and PD-L2 expression levels determine immune evasion the therapeutic efficacy of checkpoint blockade. The factors that drive inducible have been extensively studied, but mechanisms result in constitutive cancer cells are largely unknown. Methods: DNA elements were deleted by CRISPR/Cas9-mediated knockout. Protein function was inhibited chemical inhibitors. examined Western blot, mRNA real-time RT-PCR, surface protein determined cellular immunofluorescence flow cytometry....
Sustainability assessment can analyze the challenges of regional development from societal, economic, and environmental dimensions provide an important baseline for planning. Recently, rapid socio-economic Beijing-Tianjin-Hebei (BTH) urban agglomeration has inflicted great pressure on environment. Therefore, this paper evaluated sustainability dynamics BTH 2000 to 2015 at city scale using Human Sustainable Development Index (HSDI) discussed major drivers changes in sustainability. The...
The density peak clustering algorithm (DPC) requires manual determination of cluster centers, and poor performance on complex datasets with varying densities or non-convexity. Hence, a novel is proposed for the automatic selection centers based K-nearest neighbors (AKDPC). First, AKDPC classifies samples according to their mutual neighbor values into core non-core points. Second, uses average distance K nearest sample as its density. smaller is, higher Subsequently, it selects highest among...
To compare the clinical effectiveness of ultrasound-guided needle release transverse carpal ligament (TCL) with and without corticosteroid injection in tunnel syndrome (CTS). From June 2016 to 2017, 49 CTS patients (50 wrists) were included this study. Twenty-five wrists treated TCL plus (group A), 25 single B). The following parameters assessed compared including postprocedure results according relief symptoms, ultrasound (cross-sectional area median nerve at levels pisiform, flattening...
Hypoxia is a hallmark of solid cancers, including hepatocellular carcinoma (HCC). There scarce information about how hypoxia avoids immunologic stress and maintains cancer-promoting microenvironment.The Cancer Genome Atlas, RNA-seq data, Oncomine database were used to discover the correlation RNASEH2A with tumor progression; then expression mRNA protein detected in HCC tissues cells subjected or treatment CoCl2 via real-time quantitative polymerase chain reaction immunochemistry assays....
Microcystin-leucine-arginine (MC-LR) is a toxin secreted by freshwater cyanobacteria that considered potential environmental risk factor for Alzheimer's disease (AD). A previous study indicated tau protein hyperphosphorylation via phosphatase 2A (PP2A) and GSK-3β inhibition was the mechanism which MC-LR induces neurotoxicity; however, how MC-LR-induced neurotoxicity can be effectively prevented remains unclear. In this study, reversal effect of metformin on investigated. The results showed...
Abstract Objective The present study determined the feasibility and initial efficacy of a kindergarten‐based, family‐involved intervention in improving children's hand hygiene (HH) behaviors. Design A cluster‐randomized controlled trial was performed, with cluster defined as kindergarten class. Sample Participants were recruited from 20 classes six kindergartens. total 289 children their families enrolled group, 293 control group. Measurements HH behavior related knowledge survey, well data...
Recent studies have shown that ultrasound-guided injection of glucocorticoids is superior to blind puncture methods.To evaluate clinical efficacy drug in the treatment olecranon subcutaneous bursitis.From June 2016 September 2018, 45 patients diagnosed with obvious synovial effusion and treated therapy for bursitis were included this study. Under guidance ultrasound, aspiration was performed 2 ml compound betamethasone mixture injected into bursae dressed under pressure. Ultrasound...
Abstract Background: The prevalence of gout is increasing worldwide, and the symptoms acute arthritis appearing in patients seriously affect quality life. pain functional limitation caused by gouty (AGA) bring great to patients. At present, mainstream drugs have problems such as poor efficacy side effects. Traditional Chinese medicine has extensive clinical experience prevention treatment gout, it also shows clear advantages AGA. Clinical studies confirmed that si-miao-san decoction (SMSD),...
Microcystin-LR (MC-LR), the most common and toxic microcystin (MC) present in freshwater, poses a substantial threat to human health, especially hepatotoxicity. Recent evidence reveals that NLRP3 inflammasome plays an important role liver injury by activating caspase-1 promote interleukin-1β (IL-1β) secretion. In this study, we investigated possible of activation MC-LR-induced mouse inflammatory injury. We found MC-LR administered mice oral gavage mainly accumulated induced production mature...