Qin Chen

ORCID: 0000-0002-0526-2005
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About
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Research Areas
  • Glaucoma and retinal disorders
  • Corneal surgery and disorders
  • Retinal Diseases and Treatments
  • Acupuncture Treatment Research Studies
  • Acute Myeloid Leukemia Research
  • Ophthalmology and Visual Impairment Studies
  • Retinal Imaging and Analysis
  • Intraocular Surgery and Lenses
  • Anesthesia and Sedative Agents
  • Plant Gene Expression Analysis
  • Alzheimer's disease research and treatments
  • Viral gastroenteritis research and epidemiology
  • Chinese history and philosophy
  • Immune cells in cancer
  • Radiomics and Machine Learning in Medical Imaging
  • Advanced Neuroimaging Techniques and Applications
  • Intensive Care Unit Cognitive Disorders
  • Anesthesia and Pain Management
  • MRI in cancer diagnosis
  • Systemic Lupus Erythematosus Research
  • Acute Myocardial Infarction Research
  • Lymphoma Diagnosis and Treatment
  • Nausea and vomiting management
  • Cardiac Imaging and Diagnostics
  • Martial Arts: Techniques, Psychology, and Education

Zhejiang Hospital
2020-2025

Fujian Medical University
2020-2024

Union Hospital
2020-2024

University of Electronic Science and Technology of China
2018-2024

Chengdu Women's and Children's Central Hospital
2023-2024

Sichuan University
2008-2024

Harbin Veterinary Research Institute
2024

Nanjing Medical University
2015-2024

Model Animal Research Center
2018-2024

West China Hospital of Sichuan University
2008-2024

Recently, an outbreak of highly pathogenic avian influenza A (H5N1), which carries the clade 2.3.4.4b hemagglutinin (HA) gene and has been prevalent among North American bird populations since winter 2021, was reported in dairy cows United States. As May 24, 2024, virus affected 63 herds across nine states resulted two human infections. The causes unusual symptoms cows, including unexpected drop milk production, thick colostrum-like milk. Notably, US Food Drug Administration that around 20%...

10.1080/22221751.2024.2364732 article EN cc-by-nc Emerging Microbes & Infections 2024-06-04

Abstract Several groups have suggested that transplantation of marrow stromal cells (MSCs) promotes functional recovery in animal models brain trauma. Recent studies indicate tissue replacement by this method may not be the main source therapeutic benefit, as transplanted MSCs only limited ability to replace injured central nervous system (CNS) tissue. To gain insight into mechanisms responsible for such effects, we systematically investigated potential treatment injury. Using vitro studies,...

10.1002/jnr.20494 article EN Journal of Neuroscience Research 2005-05-04

This study was designed to investigate the protective effect of curcumin against d-galactose (d-gal)-induced premature ovarian failure (POF) in mice. A mouse POF model induced by subcutaneous injection d-gal (200 mg/kg/day) daily for 42 days. Mice group received both treatment and intraperitoneal (100 Ovarian function, oxidative stress apoptosis were evaluated. The P, E2 SOD levels higher, FSH, LH MDA significantly lower than those group. proportion primordial follicles also higher that In...

10.1530/jme-17-0214 article EN cc-by Journal of Molecular Endocrinology 2018-02-08

Somatic mutations of DNMT3A gene have recently been reported in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). We examined the entire coding sequences by high-resolution melting analysis sequencing Chinese patients with malignancies. R882 were found 12/182 AML 4/51 MDS, but not either 79 chronic (CML), or 57 myeloproliferative neoplasms (MPNs), 4 monomyelocytic leukemia. No other detected all patients. associated old age more frequently present monoblastic (M4 M5, 7/52)...

10.1371/journal.pone.0026906 article EN cc-by PLoS ONE 2011-10-31

β-Amyloid (Aβ) pathology is common in patients with probable dementia Lewy bodies (DLB). However, the pathologic basis and differential diagnostic performance of Aβ PET are not established DLB. Our objective was to investigate correlates

10.1212/wnl.0000000000008818 article EN cc-by-nc-nd Neurology 2019-12-21

ABSTRACT Two polyomaviruses, BK virus (BKV) and JC (JCV), are ubiquitous in the human population, generally infecting children asymptomatically then persisting renal tissue. It is thought that reactivation leads to productive infection for both viruses, with progeny shed urine. Several studies have shown rate of viruria increases age host, but a systematic approach examine shedding BKV has not been developed. To elucidate relationship between host age, we obtained urine from donors (healthy...

10.1128/jcm.01645-06 article EN Journal of Clinical Microbiology 2006-11-09

Purpose.: Somatic cells can be reprogrammed into an embryonic stem cell–like pluripotent state by Oct-3/4, Sox2, c-Myc, and Klf4. Sox2 as essential reprogramming factor also contributes to the development of eye retina. This study was conducted determine whether induced (iPS) express retinal progenitor cell (RPC)-related genes iPS directly differentiate ganglion (RGCs). Methods.: Mouse were ectopically expressed four factors in tail-tip fibroblasts (TTFs). The expression RPC-related analyzed...

10.1167/iovs.09-4504 article EN Investigative Ophthalmology & Visual Science 2010-05-19

Intra-tumoral heterogeneity (ITH) is a distinguished hallmark of cancer, and cancer stem cells (CSCs) contribute to this malignant characteristic. Therefore, it great significance investigate even target the regulatory factors driving intra-tumoral stemness. c-Myc vital oncogene frequently overexpressed or amplified in various types, including breast cancer. Our previous study indicated its potential association with cell (BCSC) biomarkers.In research, we performed immunohistochemical (IHC)...

10.1186/s12967-023-04204-5 article EN cc-by Journal of Translational Medicine 2023-06-23

Background/Aims: This study investigated the effect of consecutive superovulation on ovaries and established a premature ovarian failure (POF) model in mice. Methods: The mouse POF was induced by 5-15 treatments with pregnant mare serum gonadotropin (PMSG), human chorionic (HCG) prostaglandin F2α (PGF2α). Normal adult mice were compared displaying natural aging. following biochemical parameters measured: including follicle-stimulating hormone (FSH), luteinizing (LH), progesterone (P),...

10.1159/000495895 article EN cc-by-nc-nd Cellular Physiology and Biochemistry 2018-01-01

Patients with dementia Lewy bodies (DLB) are characterized by hypometabolism in the parieto-occipital cortex and cingulate island sign (CIS) on 18F-fluorodeoxyglucose (FDG) PET. Whether this pattern of is present as early prodromal stage DLB unknown. We investigated patients mild cognitive impairment (MCI) who progressed to probable compared MCI Alzheimer's disease (AD) clinically unimpaired (CU) controls.Patients from Mayo Clinic Disease Research Center underwent FDG PET at baseline either...

10.1016/j.nicl.2021.102754 article EN cc-by NeuroImage Clinical 2021-01-01

Objective: This retrospective analysis aimed to assess the effectiveness of auricular point acupressure therapy as an adjunct conventional treatment for noise-induced tinnitus. Methods: The study retrospectively analyzed data patients with tinnitus admitted Sandun branch Zhejiang Hospital from June 2020 2023 and included 100 analysis. Based on different treatments, were divided into a group (methylcobalamin tablets 4 weeks, n = 52) 48). baseline characteristics, loudness, hearing thresholds,...

10.4103/nah.nah_123_24 article EN cc-by-nc-sa Noise and Health 2025-01-01

Background The influence of digital financial inclusion on medical insurance systems has drawn significant attention. However, its impact China’s multilevel system (MMIS) remains uncertain. MMIS is crucial for societal wellbeing. It safeguards citizens from hardships during treatment, especially as the population ages and healthcare costs rise. By covering expenses, ensures equal access to essential services, protecting people’s health rights preventing impoverishment caused by thus...

10.3389/fpubh.2025.1586780 article EN cc-by Frontiers in Public Health 2025-04-24
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