A5065738624- Obesity, Physical Activity, Diet
- Sleep and related disorders
- Nutrition and Health in Aging
- Circular RNAs in diseases
- Health disparities and outcomes
- Cancer-related molecular mechanisms research
- Online Learning and Analytics
- Frailty in Older Adults
- Parkinson's Disease Mechanisms and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Intracranial Aneurysms: Treatment and Complications
- Geriatric Care and Nursing Homes
- Electrocatalysts for Energy Conversion
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Body Composition Measurement Techniques
- Health Systems, Economic Evaluations, Quality of Life
- Intelligent Tutoring Systems and Adaptive Learning
- Neurological Disease Mechanisms and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Gout, Hyperuricemia, Uric Acid
- Liver Disease Diagnosis and Treatment
- Cardiovascular Disease and Adiposity
- Inflammatory Myopathies and Dermatomyositis
- Neurological diseases and metabolism
- Dementia and Cognitive Impairment Research
Shandong University
2023-2025
State Key Laboratory of Chemical Engineering
2025
East China University of Science and Technology
2025
Nanjing Tech University
2025
Nanjing Brain Hospital
2024
Nanjing Medical University
2024
Fujian Medical University
2020-2023
Minjiang University
2023
First Affiliated Hospital of Chengdu Medical College
2016-2022
Sichuan University
2013-2021
Widely used catalysts for electrocatalytic hydrogen (H2) evolution reaction (HER) have high platinum (Pt) contents and show low efficiencies in neutral alkaline solutions. Herein, a carbon nanotube (CNT) supported Pt catalyst (Pt/CNT45) with 1 wt.% is fabricated. For HER, the mass activity of Pt/CNT45 acidic (18.76 A mgPt -1), (3.92 (3.88 -1) solutions respectively much higher than those on commercial Pt/C 20 (acidic: 0.31 -1, neutral: 0.03 alkaline: 0.07 -1). Thus, enhances HER not only but...
Sarcopenia is an age-related geriatric syndrome and associated with numerous adverse outcomes. Although there preponderance of studies on sarcopenia in community setting, few focused the oldest old. We investigated prevalence Chinese community-dwelling old examined socio-demographic lifestyle factors sarcopenia. also association between disability activities daily living (ADL) physical function among
Background A large number of new causative and risk genes for amyotrophic lateral sclerosis (ALS) have been identified mostly in patients European ancestry. In contrast, we know relatively little regarding the genetics ALS other ethnic populations. This study aims to provide a comprehensive analysis an unprecedented cohort Chinese mainland population correlate with clinical features rare variants carriers. Methods total 1587 patients, including 64 familial (FALS) 1523 sporadic (SALS), 1866...
Recent genetic progress has shown many causative/risk genes linked to Parkinson's disease (PD), mainly in patients of European ancestry. The study aimed investigate the PD-related and determine mutational spectrum early-onset PD ethnic Chinese.In this study, whole-exome sequencing and/or gene dosage analysis were performed 704 (EOPD) (onset age ≤45 years) 1866 controls. Twenty-six 20 other neurodegenerative lysosome diseases analysed.Eighty-two (11.6%, 82/704) EOPD carrying rare...
Objectives To explore the impact of triglyceride-glucose (TyG) index on severity coronary stenosis and risk in-hospital mortality in patients with acute ST segment elevation myocardial infarction (STEMI) after percutaneous intervention (PCI). Design A multicentre retrospective cohort study. Setting Patients STEMI undergoing PCI from three centres China 2015 to 2019. Participants total 1491 individuals presenting were enrolled. Primary outcome measure The degree was quantified by Gensini...
Experimental approaches tested to date for functional restoration of salivary glands (SGs) are tissue engineering, gene transfer, and cell therapy. To further develop these therapies, identifying specific surface markers the isolation acinar cells is needed. test a panel [used in mesenchymal stem cells, (MSCs)] localization cells.Human submandibular parotid were immunostained with MSC co-localized differentiation [α-amylase, Na-K-2Cl cotransporter-1, aquaporin-5 (AQP5)]. Additional also...
<title>Abstract</title> The turnover number (kcat) is a critical parameter in enzyme kinetics, representing the maximum of substrate molecules an can convert to product per unit time under optimal conditions. While kcat reflects enzyme's catalytic efficiency and plays central role understanding activity, existing computational models for predicting this often face significant limitations. Most rely solely on information, overlooking integral reaction itself kcat. only model that attempts...
The evaluation of the learning process is an effective way to realize personalized online learning. Real-time learners’ cognitive level during helps monitor state and adjust strategies improve quality However, most existing methods use manual coding or traditional machine methods, which are time-consuming laborious. They cannot fully mine implicit semantic information in unstructured text data, making inefficient. Therefore, this study proposed bidirectional gated recurrent convolutional...
Studies seldom combine biological, behavioral and psychological factors to estimate coronary atherosclerotic heart disease (CHD) risk.Here, we evaluated the associations between these CHD develop a predictive nomogram identify those at high risk of CHD.This case-control study included 4392 participants (1578 cases 2814 controls) in southeast China.Thirty-three variables were evaluated.Following multivariate logistic regression analysis, which revealed eight associated with CHD, was developed...
Frailty is a state of decreased resilience when person exposed to an apparently innocuous stressor that associated with numerous adverse outcomes. The aim examine frailty prevalence in China by demographic and investigate the correlation between outcome.
Background Little is known so far on the lipid profile in polymyositis (PM) patients. Our aim to identify profiles untreated patients with early PM, assess association between and C-reactive protein (a sensitive marker of inflammation) these Methods Findings This work was conducted as a case-control study. Sixty PM 60 age- sex-matched healthy controls were included. The duration less than six months, none them had received intermittent or regular corticosteroids disease-modifying...
The present study aims to investigate the complete long non-coding RNA (lncRNA) and messenger (mRNA) expression profiles in Intracranial aneurysm (IA) patients controls by sequencing, which reveals lncRNA with predictive value for IA risk.The comprehensive mRNA were detected RNA-Seq human walls superficial temporal arteries (STAs), followed bioinformatics analyses, such as GO analysis, KEGG pathway CNC network construction. Subsequently, qRT-PCR was used profile levels of selected (lncRNA...
Introduction: To study the association between specific circular RNAs and rupture of intracranial aneurysm. explore its clinical diagnostic significance synergistic effects with individual environmental influencing factors. Methods: Three hundred forty seven cases controls were included in this study. Multivariate analysis was used to main Intracranial aneurysm related screened based on sequencing verified peripheral blood by PCR. ROC curve, logistic regression model fork association,...
Residential surrounding greenness may be protective of dyslipidemia are often theorized but remain poorly quantified. In particular, the underlying biological mechanisms blood lipid changes with green spaces unclear.Our observational epidemiology study included a residentially stable sample 1035 coronary heart disease patients, and proteomics 16 participants. Normalized Difference Vegetation Index (NDVI) was used to evaluate residential exposures. Proteomics technology identify plasma...
<b><i>Background/Aims: </i></b>Both kidney dysfunction and cognitive impairment are common problems in hypertensive patients. However, few studies have explored the association between these conditions patients aged 80 or over. The current study was undertaken to determine impact of chronic disease (CKD) estimated glomerular filtration rate (eGFR) on among an 80-year-old population with untreated hypertension China. <b><i>Methods: </i></b>A...