- Lymphoma Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Hematopoietic Stem Cell Transplantation
- Myasthenia Gravis and Thymoma
- Oral health in cancer treatment
- Diabetes Treatment and Management
- Extracellular vesicles in disease
- Mesenchymal stem cell research
- Metabolism, Diabetes, and Cancer
- CNS Lymphoma Diagnosis and Treatment
- Ubiquitin and proteasome pathways
- Nanoplatforms for cancer theranostics
- Monoclonal and Polyclonal Antibodies Research
- Blood groups and transfusion
- T-cell and B-cell Immunology
- Photodynamic Therapy Research Studies
- Health, Environment, Cognitive Aging
- Multiple Myeloma Research and Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Ferroptosis and cancer prognosis
- Chronic Lymphocytic Leukemia Research
- Peripheral Neuropathies and Disorders
- Blood properties and coagulation
- Apelin-related biomedical research
- Porphyrin and Phthalocyanine Chemistry
Xi'an Jiaotong University
2025
Affiliated Hospital of Qingdao University
2016-2024
Qingdao University
2016-2024
Second Affiliated Hospital of Nanjing Medical University
2023-2024
Hebei General Hospital
2020-2023
Hebei Medical University
2017-2022
Chinese People's Liberation Army
2016-2022
Ningbo Academy of Agricultural Sciences
2022
Fourth Hospital of Hebei Medical University
2017-2022
Hospital of Hebei Province
2020
Outcomes of haploidentical hematopoietic cell transplantation (haplo-HCT) with post-transplant cyclophosphamide (PT-Cy) have greatly improved. It remains unknown whether haplo-HCT PT-Cy was associated poor outcomes when compared HLA-matched HCT. To address this issue, we performed a meta-analysis to compare those HCT.A systematic search for case-control studies were in PubMed, Embase and Cochrane Library databases. Using random model, the risk ratios (RRs) 95% confidence intervals (95% CI)...
Bone marrow biopsy, the gold standard for diagnosis of multiple myeloma (MM), has main limitation invasiveness. Here, we explored diagnostic and prognostic values circulating miR-1246 in patients with MM.Ninety MM 30 healthy donors (control group) were recruited this study. The expression peripheral blood samples was detected using qPCR. receiver operating characteristic (ROC) curve used to assess value MM. Kaplan-Meier survival analyze performed evaluate miR-1246.The level serum from newly...
Background Aging is one of the most important public health issues. Previous studies on factors affecting aging focused genetics and lifestyle, but association between polycyclic aromatic hydrocarbons (PAHs) still unclear. Methods This study utilized data from National Health Nutrition Examination Survey (NHANES) 2003–2010. A total 8,100 participants was used to construct biological age predictors by using recent advanced algorithms Klemera–Doubal method (KDM) Mahalanobis distance. Two...
The hypoglycemic drug GLP-1 receptor agonist can ameliorate hepatic steatosis but the mechanism is not clear. Intake of high fructose leads to non-alcoholic fatty liver disease by stimulating lipid synthesis, and β-catenin key molecule for realizing function in extrahepatic tissues; with discovery liver, we speculate that might mediate on ameliorating induced fructose. Wistar rats were fed diet 8 weeks then treated exenatide 4 weeks; changes synthesis pathway factors, expression nuclear...
Abstract To analyze the short-term clinical effect of photodynamic therapy on bronchial lung cancer and provide relevant practical experience for its better application in practice. Twenty patients with diagnosed by pathology were treated or interventional tumor reduction combined therapy. Follow-up at 3 months after treatment, chest CT bronchoscopy reexamined. The lesions observed under a microscope, pathological specimens living tissues stained HE TUNEL to evaluate effect. volume trachea...
Oral mucositis (OM) affects the quality of life and therapeutic outcomes cancer patients. More effective drugs methods for treating OM are urgently required clinical application. Extracellular vesicles can play important roles in cutaneous wound healing. However, their role remains unclear. Our aim was to investigate function mechanisms topical coatings extracellular derived from human umbilical cord mesenchymal stem cells (hUC-MSC-EVs) OM.HUC-MSC-EVs were isolated by differential...
BACKGROUND There is currently little information on haploidentical hematopoietic cell transplantation (haplo-HCT) for T-lymphoblastic lymphoma (T-LBL). Data about peripheral blood stem cells (PBSC) as a reliable graft source T-LBL treatment are lacking. MATERIAL AND METHODS patients who underwent T cell-replete (haplo-PBHCT) from July 2007 to January 2017 were retrospectively evaluated. RESULTS A total of 25 (age ≥15 years) with median age 24 (range 15-51) years enrolled. The number CD34+...
In recent years, the beneficial effects of silibinin (SIL) on nonalcoholic fatty liver disease (NAFLD) have attracted widespread attention. We tried to study intervention effect SIL NAFLD, and explore potential mechanisms targets NAFLD improvement. Thirty-three male C57BL6/J mice were divided into three groups, and, respectively, fed a normal diet (ND), high-fat (HFD) or HFD given treatment (HFD+SIL). Biochemical indexes histopathological changes in each group detected. addition,...
To investigate the effects of photodynamic therapy (PDT) mediated by hematoporphyrin derivatives (HPD) on proliferation small cell lung cancer H446 cells and bronchial epithelial BEAS-2B cells. were cultured in vitro with different concentrations HPD(0, 5, 10, 12, 15, 20 μg/mL) for 4 h, then irradiated 630 nm laser energy densities (0, 25, 50, 75, 100 mW/cm2). Cell viability detected CCK8 assay. The apoptosis was observed Annexin V-FTTC/PI double staining Hoechst 33258. RT-PCR examination...