Zhe Gao

ORCID: 0000-0001-5087-349X
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About
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Research Areas
  • Lymphoma Diagnosis and Treatment
  • Liver Disease Diagnosis and Treatment
  • Hematopoietic Stem Cell Transplantation
  • Myasthenia Gravis and Thymoma
  • Oral health in cancer treatment
  • Diabetes Treatment and Management
  • Extracellular vesicles in disease
  • Mesenchymal stem cell research
  • Metabolism, Diabetes, and Cancer
  • CNS Lymphoma Diagnosis and Treatment
  • Ubiquitin and proteasome pathways
  • Nanoplatforms for cancer theranostics
  • Monoclonal and Polyclonal Antibodies Research
  • Blood groups and transfusion
  • T-cell and B-cell Immunology
  • Photodynamic Therapy Research Studies
  • Health, Environment, Cognitive Aging
  • Multiple Myeloma Research and Treatments
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Ferroptosis and cancer prognosis
  • Chronic Lymphocytic Leukemia Research
  • Peripheral Neuropathies and Disorders
  • Blood properties and coagulation
  • Apelin-related biomedical research
  • Porphyrin and Phthalocyanine Chemistry

Xi'an Jiaotong University
2025

Affiliated Hospital of Qingdao University
2016-2024

Qingdao University
2016-2024

Second Affiliated Hospital of Nanjing Medical University
2023-2024

Hebei General Hospital
2020-2023

Hebei Medical University
2017-2022

Chinese People's Liberation Army
2016-2022

Ningbo Academy of Agricultural Sciences
2022

Fourth Hospital of Hebei Medical University
2017-2022

Hospital of Hebei Province
2020

Outcomes of haploidentical hematopoietic cell transplantation (haplo-HCT) with post-transplant cyclophosphamide (PT-Cy) have greatly improved. It remains unknown whether haplo-HCT PT-Cy was associated poor outcomes when compared HLA-matched HCT. To address this issue, we performed a meta-analysis to compare those HCT.A systematic search for case-control studies were in PubMed, Embase and Cochrane Library databases. Using random model, the risk ratios (RRs) 95% confidence intervals (95% CI)...

10.18632/oncotarget.18862 article EN Oncotarget 2017-06-29

Bone marrow biopsy, the gold standard for diagnosis of multiple myeloma (MM), has main limitation invasiveness. Here, we explored diagnostic and prognostic values circulating miR-1246 in patients with MM.Ninety MM 30 healthy donors (control group) were recruited this study. The expression peripheral blood samples was detected using qPCR. receiver operating characteristic (ROC) curve used to assess value MM. Kaplan-Meier survival analyze performed evaluate miR-1246.The level serum from newly...

10.1080/16078454.2022.2095890 article EN cc-by Hematology 2022-07-06

Background Aging is one of the most important public health issues. Previous studies on factors affecting aging focused genetics and lifestyle, but association between polycyclic aromatic hydrocarbons (PAHs) still unclear. Methods This study utilized data from National Health Nutrition Examination Survey (NHANES) 2003–2010. A total 8,100 participants was used to construct biological age predictors by using recent advanced algorithms Klemera–Doubal method (KDM) Mahalanobis distance. Two...

10.3389/fpubh.2024.1379252 article EN cc-by Frontiers in Public Health 2024-06-05

The hypoglycemic drug GLP-1 receptor agonist can ameliorate hepatic steatosis but the mechanism is not clear. Intake of high fructose leads to non-alcoholic fatty liver disease by stimulating lipid synthesis, and β-catenin key molecule for realizing function in extrahepatic tissues; with discovery liver, we speculate that might mediate on ameliorating induced fructose. Wistar rats were fed diet 8 weeks then treated exenatide 4 weeks; changes synthesis pathway factors, expression nuclear...

10.4081/ejh.2020.3160 article EN cc-by-nc European Journal of Histochemistry 2020-09-15

Abstract To analyze the short-term clinical effect of photodynamic therapy on bronchial lung cancer and provide relevant practical experience for its better application in practice. Twenty patients with diagnosed by pathology were treated or interventional tumor reduction combined therapy. Follow-up at 3 months after treatment, chest CT bronchoscopy reexamined. The lesions observed under a microscope, pathological specimens living tissues stained HE TUNEL to evaluate effect. volume trachea...

10.1007/s10103-020-03080-5 article EN cc-by Lasers in Medical Science 2020-06-27

Oral mucositis (OM) affects the quality of life and therapeutic outcomes cancer patients. More effective drugs methods for treating OM are urgently required clinical application. Extracellular vesicles can play important roles in cutaneous wound healing. However, their role remains unclear. Our aim was to investigate function mechanisms topical coatings extracellular derived from human umbilical cord mesenchymal stem cells (hUC-MSC-EVs) OM.HUC-MSC-EVs were isolated by differential...

10.21037/atm-22-767 article EN Annals of Translational Medicine 2022-03-01

BACKGROUND There is currently little information on haploidentical hematopoietic cell transplantation (haplo-HCT) for T-lymphoblastic lymphoma (T-LBL). Data about peripheral blood stem cells (PBSC) as a reliable graft source T-LBL treatment are lacking. MATERIAL AND METHODS patients who underwent T cell-replete (haplo-PBHCT) from July 2007 to January 2017 were retrospectively evaluated. RESULTS A total of 25 (age ≥15 years) with median age 24 (range 15-51) years enrolled. The number CD34+...

10.12659/aot.909122 article EN Annals of Transplantation 2018-06-22

In recent years, the beneficial effects of silibinin (SIL) on nonalcoholic fatty liver disease (NAFLD) have attracted widespread attention. We tried to study intervention effect SIL NAFLD, and explore potential mechanisms targets NAFLD improvement. Thirty-three male C57BL6/J mice were divided into three groups, and, respectively, fed a normal diet (ND), high-fat (HFD) or HFD given treatment (HFD+SIL). Biochemical indexes histopathological changes in each group detected. addition,...

10.1080/21655979.2022.2045837 article EN Bioengineered 2022-03-01

To investigate the effects of photodynamic therapy (PDT) mediated by hematoporphyrin derivatives (HPD) on proliferation small cell lung cancer H446 cells and bronchial epithelial BEAS-2B cells. were cultured in vitro with different concentrations HPD(0, 5, 10, 12, 15, 20 μg/mL) for 4 h, then irradiated 630 nm laser energy densities (0, 25, 50, 75, 100 mW/cm2). Cell viability detected CCK8 assay. The apoptosis was observed Annexin V-FTTC/PI double staining Hoechst 33258. RT-PCR examination...

10.1007/s10103-024-04013-2 article EN cc-by Lasers in Medical Science 2024-02-17
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