- Vector-borne infectious diseases
- Yersinia bacterium, plague, ectoparasites research
- Viral Infections and Vectors
- Insect and Pesticide Research
- Diphtheria, Corynebacterium, and Tetanus
- Hepatitis Viruses Studies and Epidemiology
- Bacillus and Francisella bacterial research
- Parasitic Infections and Diagnostics
- Vector-Borne Animal Diseases
- Salmonella and Campylobacter epidemiology
- Leptospirosis research and findings
- Molecular Biology Techniques and Applications
- Rabies epidemiology and control
- Respiratory viral infections research
Saint Petersburg Pasteur Institute
2016-2023
Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
2019-2020
At the crossroad between Europe, Asia, and Africa, Bulgaria is part of Mediterranean - Black Sea Flyway (MBSF) used by millions migratory birds. In this study, bird species migrating through were investigated as carriers zoonotic pathogens. total, 706 birds belonging to 46 checked for presence various bacterial pathogens (Campylobacter, Yersinia, Salmonella, Listeria, Escherichia coli, Staphylococcus aureus, Francisella tularensis, Coxiella burnetii, Borrelia burgdorferi, Brucella spp.)....
Coxiella burnetii is an obligate intracellular gram-negative bacterial pathogen, ethiological agent of Q-fever, a zoonotic disease, elapsing as acute (mostly atypical pneumonia) or chronic endocarditis) form. The host range represented by wide mammal, avian and arthropod species, but the main source human infection are farm animals. route aerosolic. In case contact with organism pathogen binds phagocytal monocytic-macrophagal cell line. C. promotes maturation specific phagolysosome-like...
Aim. Comparison of diagnostic capabilities 2 variants PCR for detection Coxiella burnetii persistence in dynamics infectious process patients with Q fever. Materials and methods. 110 samples clinical material, obtained from fever an endemic region this infection (Astrakhan region), were studied. The studied a standard (marker - 16S rRNA gene fragment) real-time (RT-PCR) groEL fragment). Results. Both markers established to be perspective C. DNA RT-PCR detects positive result including late...
Tick-borne bacterial and viral infections are widespread in middle latitudes of the Northern hemisphere. Natural foci such coincide with geographic areas inhabited by ixodid ticks. Ixodid tick-borne borreliosis is a pressing issue for some territories Russia, especially North-Western Federal District St. Petersburg megalopolis as well adjacent Leningrad District, where people may become infected after tick bite recreational zones suburban park areas. Currently, very few publications...
This article describes a lethal case of leptospirosis that occurred in Southern Russia. The Leptospira strain was isolated and characterized using microscopic agglutination test, MALDI-TOF mass spectrometry, targeted PCR, high-throughput sequencing. We show molecular mass-spectrometry methods can be an alternative to conventional diagnostics study, which require highly qualified staff performed only at specialized laboratories. also report the first whole genome L. interrogans
This is the announcement of a draft genome sequence Coxiella burnetii strain Leningrad-2, phase I. The strain, which mildly virulent in infected guinea pigs, was isolated 1957 from blood patient with acute Q fever Leningrad (now Saint Petersburg), Russia.
Tick-borne infections are the most common group of zooanthroponotic diseases in Northern Hemisphere. For Baltic Sea region and Fennoscandia, dominant infectious pathologies transmitted by ticks tick-borne borreliosis tick- borne encephalitis. The presence vast forested areas, actively visited people St. Petersburg Leningrad region, contributes to a rather high level encroachment on flares intelligence encephalitis among population these regions. relatively dangerous pathogens that can be...
Background. Q fever, or coxiellosis, is a natural focal disease characterized by polymorphism of clinical signs and can affect not only humans but also many species animals. This infection spread almost all over the world. On African continent, foci coxiellosis endanger local population people arriving for temporary stay. Given that sick agricultural animals their ectoparasites are markers presence in region, study latter may be relevant to identify potential fever.
 work aimed Coxiella...
The causative agent of Q fever, the intracellular pathogen Coxiella burnetii , is found almost worldwide; many types blood-sucking ticks that are dangerous to animals and humans involved in circulation pathogen. Using molecular-genetic methods, closely related species microorganisms genus sp. have been discovered, some which endo-symbionts ticks, can survive human body, causing an infectious process. existence whose genes similar nucleotide sequence those C. makes it difficult diagnose...
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