A5035886426- Viral Infections and Vectors
- Tuberculosis Research and Epidemiology
- Yersinia bacterium, plague, ectoparasites research
- Vector-borne infectious diseases
- Mosquito-borne diseases and control
- Soil and Environmental Studies
- Bacteriophages and microbial interactions
- Coal and Coke Industries Research
- Marine and environmental studies
- Systemic Sclerosis and Related Diseases
- Immune responses and vaccinations
- Environmental and Biological Research in Conflict Zones
- Virology and Viral Diseases
- Parasitic Diseases Research and Treatment
- Synthesis and Characterization of Heterocyclic Compounds
- Regional Socio-Economic Development Trends
- Indigenous Studies and Ecology
- Urticaria and Related Conditions
- Human Health and Disease
- Genomics and Phylogenetic Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Healthcare Systems and Public Health
- Vector-Borne Animal Diseases
- Mycobacterium research and diagnosis
- Zoonotic diseases and public health
Astrakhan State Medical University
2012-2021
Ministry of Health of the Russian Federation
2019
From July to September 1999, a widespread outbreak of meningoencephalitis associated with West Nile virus (Flavivirus, Flaviviridae) occurred in southern Russia, hundreds cases and dozens deaths. Two strains isolated from patient serum brain-tissue samples reacted hemagglutination-inhibition neutralization tests patients' convalescent-phase sera immune ascites fluid other virus.
We have developed a phagebiotic composition using 8 virulent bacteriophages (2 strains of each species) which are able to lyse Acinetobacter baumannii, Klebsiella pneumoniae, Pseudomonas aeruginosa and Staphylococcus aureus. The unique character the is ensured by particular properties bacteriophage comprising preparation, including their range lytic activity toward specific bacterial pathogens, morphology plaques, cycle development, restriction profile DNAs, specificity genomes (based on...
Alpha-fetoprotein represents the most prominent oncobiomarker, widely used in diagnosis of hepatocellular carcinoma for monitoring tumor progression, presence metastasis, assessment cancer prognosis and successful antitumor therapeutic measures. Yuri Semenovich Tatarinov is a Russian scientist who first published antigen specific human 1963. To commemorate 50th anniversary discovery alpha-fetoprotein, 9th International Scientific- Practical Conference entitled ?Achievements fundamental...
The article presents the study of frequency unfavorable side effects to anti-tuberculosis drugs in new pulmonary tuberculosis patients Regional Clinical TB Dispensary Astrakhan 2012-2013. reflects type and nature specific drugs. It has been found out that effect occur more often case combination compared one efficiency therapy demonstrated.
Aim. Comparison of diagnostic capabilities 2 variants PCR for detection Coxiella burnetii persistence in dynamics infectious process patients with Q fever. Materials and methods. 110 samples clinical material, obtained from fever an endemic region this infection (Astrakhan region), were studied. The studied a standard (marker - 16S rRNA gene fragment) real-time (RT-PCR) groEL fragment). Results. Both markers established to be perspective C. DNA RT-PCR detects positive result including late...
In 178 patients with different clinical forms of pulmonary tuberculosis carried out pharmacogenetic testing to determine gene polymorphism glutathione S-transferase system (GSTM1, GSTT1). Estimated the severity and duration manifestations syndrome intoxication, depending on It was found that combination “zero” develop genotypes GSTM1 GSTT1 enzyme is a predictor symptoms intoxication persisting.
There are presented results of the clinical follow-up 64 patients with moderate course coxiellosis in whom circulating immune complexes blood serum have been determined. All received routine therapy, 29 were administered cycloferon intramuscularly, dose 2 ml, on 1st, 2nd, 4th, 6th and 8th day treatment. Clinical evidences under treatment seen to be longer older than 50. Complex therapy use shortened longevity disease. By this dependence duration age disappeared. Content different sizes was...
Purpose of the study: Analyze epidemiological situation echinococcosis in children Astrakhan region. In region from 2001 to 2016. Registered 141 cases humans, incl. — 22 (15,6%). Among all sick children, was more often reported school-age persons 90,9%. From preschool age group, recorded two (9,1%) unorganized aged 5 and 6 years. The main complaints majority invasive were pain a feeling heaviness right hypochondrium 40,9%, periodically arising cramping area localization parasite 31,8%. rare...
Ярмухамедова Н.А. 2 , Галимзянов Х.М. 1 Черенова Л.П. 1В работе представлены современные дифференциально-диагностические критерии постановки диагноза Крымской геморрагической лихорадки, вызванной вирусом Конго (КГЛ), и кори, позволяющие своевременно поставить диагноз проводить раннюю адекватную терапию.Определены сигнальные эпидемиологические признаки, которые могут указывать на наличие КГЛ,присасывание или контакт с клещом, обнаружение специфического первичного аффекта, весенне-летний сезон...
Журнал для непрерывного медицинского образования врачей Случай завозной тропической малярии у жителя АстраханиВ ПОМОЩЬ ПРАКТИКУЮЩЕМУ ВРАЧУ Федеральное государственное бюджетное образовательное учреждение выс
Objective: To study the spontaneous production of proinflammatory cytokines (TNF-α and IL-1β) in newly diagnosed patients with different clinical forms pulmonary tuberculosis, Russian population groups living Astrakhan region. Materials Methods: on basis hospital № 1 "Regional Clinical TB Dispensary" Astrakhan, performed a comprehensive immunological examination 60 tuberculosis. Men 44 (73.3%), 16 women (26.7%). Age – from 18 to 56 years. Residents city was 29 (48.3%), rural area 31 (51.7%)....
The paper presents the results of a clinical observation and complex examination 48 patients with Q-fever, blood samples from 20 them were tested for lysozyme, complement, circulating immune complexes (CIC). swing disease was characterized by maximum manifestations disease. Early reconvalescence marked decrement in symptoms gradual recovery body's impaired functions. study indicated relationship between level nonspecific resistance factors stage pathologic process. showed an increase amount...
Aim. To study the peculiar features of roentgenological picture pulmonary tuberculosis in patients with polymorphous HLA-DRB1 allels genotype associations pro-and-antiinflammatory cytokines concentration.
 Materials and methods. The complex clinicoimmunogenetic examination 64 was carried out. patients’ age ranged 18 to 52 years. gene polymorphism determined using method polymerase chain reaction DNA, previously extracted from blood samples. Cytokine concentration peripheral before...
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Aim. To study radiological features of pulmonary tuberculosis according to the polymorphism gene HLA-DRB1. Materials and methods. Radiologically examined 73 newly diagnosed patients with different clinical forms genotyped for HLA-DRB1 by PCR-MSSR. Results. The analysis associations specificities HLA-DRB1* depending on x-ray picture disease. It is found that specificity (*04, *11, *13, *14 *16 HLA- DRB1 *) positively associated amount a specific process more than three segments destruction...
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Клинические и эпидемиологические особенности малярии у детей в Астраханской области Р.С.Аракельян 1 , Х.М.Галимзянов О.В.Коннова Г.Л.Шендо 2 Л.Е.Войнова ФГБОУ ВО «Астраханский государственный медицинский университет» Минздрава России ФБУЗ «Центр гигиены эпидемиологии области» Цель исследования: анализ клинико-эпидемиологической ситуации по среди области.Дизайн: одномоментное ретроспективное исследование
Purpose: assessment of the clinical and epidemiological situation current invasions in children Astrakhan region. 315 outpatient cards were analyzed 2016. The diagnosis Giardiasis was made to 151 children, Enterobiasis — 164. age all observed ranged from 9 months 17 years. largest part up aged 3 14 years 80.3%, among them enterobiasis identified 46.7%, giardiasis 33.6% cases. Most 90.5% organized groups (they attended preschool institutions or school). reasons for examination varied. Some...