- Plant Disease Resistance and Genetics
- Fungal Plant Pathogen Control
- Fungal and yeast genetics research
- Plant Pathogens and Fungal Diseases
- Plant-Microbe Interactions and Immunity
- Plant-Derived Bioactive Compounds
- Garlic and Onion Studies
- Agriculture, Plant Science, Crop Management
- Mycorrhizal Fungi and Plant Interactions
- Antibiotic Resistance in Bacteria
- Galectins and Cancer Biology
- Fungal Infections and Studies
- Alcohol Consumption and Health Effects
- Plant Pathogens and Resistance
- Evolution and Genetic Dynamics
- Seed Germination and Physiology
- Biocrusts and Microbial Ecology
- Nitrogen and Sulfur Effects on Brassica
- Cannabis and Cannabinoid Research
- Microbial Community Ecology and Physiology
- Bacterial Identification and Susceptibility Testing
- Microbial Natural Products and Biosynthesis
- Genomics, phytochemicals, and oxidative stress
- Plant and animal studies
- Signaling Pathways in Disease
Université Laval
2018-2025
Assistance Publique – Hôpitaux de Paris
2022
Hôpital Armand-Trousseau
2022
Sorbonne Université
2022
Institut Agro Rennes-Angers
2017-2022
L'Institut Agro
2021
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2021
Université d'Angers
2012-2019
PROTEO
2018
Institut de Recherche en Horticulture et Semences
2012-2018
Abstract The extended endocannabinoid system, also termed endocannabinoidome, participates in multiple metabolic functions health and disease. Physical activity can both have an acute chronic impact on mediators, as does diet. In this crossover randomized controlled study, we investigated the influence of diet peripheral response to maximal aerobic exercise a sample active adult women (n = 7) with no underlying conditions. We compared 7-day standardized Mediterranean (MedDiet) control...
ABSTRACT Alternaria brassicicola causes dark spot (or black spot) disease, which is one of the most common and destructive fungal diseases Brassicaceae spp. worldwide. Here, we report draft genome sequence strain Abra43. The assembly comprises 29 scaffolds, with an N 50 value 2.1 Mb. assembled was 31,036,461 bp in length, a G+C content 50.85%.
Background/Objectives: The global spread of carbapenem-resistant Pseudomonas aeruginosa (CRPA) warrants collaborative action. Guidance should come from integrated One Health surveillance; however, a surveillance strategy is currently unavailable due to insufficient knowledge on the sources and transmission routes CRPA. aim SAMPAN study (“A Smart Surveillance Strategy for Carbapenem-resistant aeruginosa”) develop globally applicable strategy. Methods: First, an international cross-sectional...
Abstract Alternaria dauci is a Dothideomycete fungus, causal agent of carrot leaf blight. As member the genus, known to produce lot secondary metabolite toxins, A. also supposed synthetize host specific and non-host toxins playing crucial role in pathogenicity. This study provides first reviewing metabolism genetic basis genus by prediction 55 different putative core genes. Interestingly, aldaulactone, phytotoxic benzenediol lactone from , was demonstrated as important pathogenicity partial...
Flavin-dependent monooxygenases are involved in key biological processes as they catalyze a wide variety of chemo-, regio- and enantioselective oxygenation reactions. Flavoprotein frequently encountered micro-organisms, most which require further functional biocatalytic assessment. Here we investigated the function AbMak1 gene, encodes group A flavin monooxygenase plant pathogenic fungus Alternaria brassicicola, by generating deficient mutant examining its phenotype. Functional analysis...
Alternaria brassicicola causes black spot disease in Brassicaceae . During host infection, this necrotrophic fungus is exposed to various antimicrobial compounds, such as the phytoalexin brassinin which produced by many cultivated Brassica species. To investigate cellular mechanisms compound toxicity and corresponding fungal adaptive strategies, we first analyzed transcriptional responses short-term exposure then used additional functional approaches. This study supports hypothesis that...
Summary Nostoc (Nostocales, Cyanobacteria) has a global distribution in the Polar Regions. However, genomic diversity of is little known and there are no genomes available for polar . Here we carried out first analysis commune morphotype with recent sample from High Arctic herbarium specimen collected during British Expedition (1875–76). Comparisons 26 present‐day non‐polar members Nostocales family highlighted that pronounced genetic variations among strains species. Osmoprotection other...
Abstract Maple sap is a complex nutrient matrix collected during spring to produce maple syrup. The characteristics of change over the production period and its composition directly impacts syrup quality. This variability could in part be attributed changes tree metabolism following dormancy release, but little known about these deciduous trees. Therefore, understanding variation associated with release help pinpoint causes some defects In particular, defect as “buddy”, an increasing concern...
Abstract While the use of barcoded collections laboratory microorganisms and development barcode‐based cell tracking are rapidly developing in genetics genomics research, tools to track natural populations still lacking. The yeast Saccharomyces paradoxus is an emergent microbial model ecology evolution. More than five allopatric sympatric lineages have been identified hundreds strains isolated for this species, allowing assess impact diversity on complex traits. We constructed a collection...
Abstract Background MCC/eisosomes are membrane microdomains that have been proposed to participate in the plasma function particular by regulating homeostasis of lipids, promoting recruitment specific proteins and acting as provider reservoirs. Results Here we showed several potential MCC/eisosomal protein encoding genes necrotrophic fungus A. brassicicola were overexpressed when germinated spores exposed antimicrobial defence compounds, osmotic hydric stresses, which major constraints...
Alternaria brassicicola is a necrotrophic fungus causing black spot disease and an economically important seed-borne pathogen of cultivated brassicas. Seed transmission crucial component its parasitic cycle as it promotes long-term survival dispersal. Recent studies, conducted with the Arabidopsis thaliana/A. pathosystem, showed that level susceptibility to water stress strongly influenced seed ability. In this study, we gained further insights into mechanisms involved in infection process...
Maple syrup, an emblematic food product of Canada is produced from the concentration sap collected maple trees during spring. During this season, come out dormancy, which modifies composition. Meanwhile, microorganisms that contaminate as it can also modify its As these two factors impact quality we aimed to better understand how microbial communities vary along dormancy release. We estimated absolute abundance bacteria and fungi in a release index using high-throughput amplicon sequencing...
Abstract Microbial interactions contribute to shape ecosystems and their functions. The interplay between microorganisms also shapes the evolutionary trajectory of each species, by imposing metabolic physiological selective pressures. mechanisms underlying these are thus interest improve our understanding microbial evolution at genetic level. Here we applied a functional genomics approach in model yeast Saccharomyces cerevisiae identify fitness determinants naïve biotic interactions. We used...
Abstract Familial platelet disorder with associated myeloid malignancy (FPD‐MM; OMIM 601399) is related to germline RUNX1 mutation. The pathogenicity of variants was initially linked FPD‐MM phenotype, but the discovery new through expansion genetic explorations in leukaemia questioning this assertion. In study, we add 10 families variant explored at Armand Trousseau Hospital for diagnosis or thrombocytopenia, 259 described so far. Detailed description their personal and family history...