A5028585834- Bone fractures and treatments
- Pelvic and Acetabular Injuries
- Hip and Femur Fractures
- Inflammatory Myopathies and Dermatomyositis
- Osteoarthritis Treatment and Mechanisms
- Pregnancy and preeclampsia studies
- Shoulder and Clavicle Injuries
- Total Knee Arthroplasty Outcomes
- Orthopedic Surgery and Rehabilitation
- Hip disorders and treatments
- Diabetic Foot Ulcer Assessment and Management
- Elbow and Forearm Trauma Treatment
- Muscle and Compartmental Disorders
- Orthopaedic implants and arthroplasty
- Birth, Development, and Health
- Orthopedic Infections and Treatments
- Abdominal Trauma and Injuries
- Shoulder Injury and Treatment
- Pregnancy-related medical research
- Wound Healing and Treatments
- Organ and Tissue Transplantation Research
- Muscle Physiology and Disorders
- Spinal Fractures and Fixation Techniques
- Reconstructive Surgery and Microvascular Techniques
- Nasolacrimal Duct Obstruction Treatments
First Affiliated Hospital of Bengbu Medical College
2011-2025
Novartis (United States)
2017-2025
Zhongda Hospital Southeast University
2025
Brigham and Women's Hospital
2021
Bengbu Medical College
2016-2021
University College London
2021
Wuhan University
2018
Wuhan Donghu University
2018
Nanjing University
2018
Nanjing General Hospital of Nanjing Military Command
2018
<h3>Objective</h3> To assess long-term (2 years) effects of bimagrumab in participants with sporadic inclusion body myositis (sIBM). <h3>Methods</h3> Participants (aged 36–85 who completed the core study (RESILIENT [Efficacy and Safety Bimagrumab/BYM338 at 52 Weeks on Physical Function, Muscle Strength, Mobility sIBM Patients]) were invited to join an extension study. Individuals continued same treatment as (10 mg/kg, 3 1 mg/kg or matching placebo administered IV infusions every 4 weeks)....
To investigate the effectiveness of digital three-dimensional (3D) printing osteotomy guide plate assisted total knee arthroplasty (TKA) in treatment osteoarthritis (KOA) patients with femoral internal implants. The clinical data 55 KOA who met selection criteria between July 2021 and October 2023 were retrospectively analyzed. Among them, 26 cases combined implants treated 3D TKA (guide group), 29 conventional (control group). There was no significant difference gender, age, body mass...
Primary hyperoxaluria (PH) is a rare autosomal recessive disorder that results from the overproduction of endogenous oxalate. The diagnosis PH often delayed or missed owing to its rarity, variable clinical expression and other diagnostic challenges. In this study, we report patient with frameshift variant, c.823_824dup, in alanine-glyoxylate aminotransferase (AGXT) gene PH1 who presented renal failure recurrence after kidney transplantation, arteriovenous fistula (AVF) occlusion subcutaneous...
Objective To compare the clinical efficacy of pararectus and ilioinguinal approach in treatment acetabular fractures. Methods A retrospective analysis data 60 patients with fractures treated by or from January 2016 to 2019 was performed record all comparing length surgical incision, time expose fracture amount blood loss during operation. Patients were routinely followed up at 1, 6 12 months postoperatively. The function hip joint after operation (Improved Merle d' Aubigne Postel scores)...
Abstract Background To explore the clinical characteristics of patients with unstable pelvic fractures combined acetabular and to discuss treatment strategies for such help guide treatment. Methods We retrospectively assessed 24 admitted our hospital from June 2018 2022 fractures, including 15 male 9 female a mean age 44.8 years. According Tile fracture classification, cases were type B, C. The classified using Letournel–Judet classification. There 8 transverse 4 posterior wall 3 anterior...
Nicotine has negative effects on tissue repair, little research concerns its effect the cartilage repair of engineering stem cells. The present study aimed to investigate nicotine bone marrow-derived mesenchymal cells' (BMSCs) chondrogenic function defects and explored molecular mechanism. A defect model rat was repaired by BMSC transplantation, treated with or saline at 2.0 mg/kg/d in 12 weeks. Nicotine's differentiation studied exposing BMSCs 0.1, 1, 10, 100 μM, methyllycaconitine (MLA),...
Disruption of normal barrier function is a fundamental factor in the pathogenesis inflammatory bowel disease, and intestinal stem cell (ISC) transplantation may be an optional treatment for patients. However, it complicated inefficient to isolate ISCs from intestine, which hampers its wide application clinic. We developed two-step protocol mesenchymal cells (MSCs) were first induced into Sox17- or Foxa2-positive definitive endoderm by activin A then Lgr5-positive ISC-like miR-17 FGF2...
To evaluate the effectiveness of three-dimensional (3-D) printing assisting minimally invasive for intraarticular calcaneal fractures with percutaneous poking reduction and cannulate screw fixation.A retrospective analysis was performed 19 patients (19 feet) fracture who had been treated between March 2015 May 2016. There were 13 males 6 females an average age 38.2 years (range, 24-73 years). 3 open 16 closed fractures. By Sanders classification, 12 cases type Ⅱ, 7 Ⅲ. Essex-Lopresti tongue...
To examine efficacy and safety of bimagrumab (BYM338)in patients with sporadic inclusion body myositis (sIBM) measured by physical function, muscle strength, mass.
Serum levels of endoglin were measured in pre-eclamptic women their third trimester and second who later developed preeclampsia. Placental at birth also determined preeclamptic healthy controls. was significantly higher the than controls (median 35.15 versus 10.35 ng/ml, respectively) with severe compared mild pre-eclampsia 51.68 20.99 respectively). 26.24 9.21 ng/mg, 28.77 13.38 Pregnant eventually had serum age- gestational age-matched 5.90 5.20 These findings suggest that plays an...
To investigate and analyze the effectiveness of internal fixation with two different cannulated screw implanting methods rhomboid inverted triangle in treatment femoral neck fracture young adults.The clinical data 38 adults who met selection criteria between January 2018 August 2019 were retrospectively analyzed. According to implanting, patients divided into groups, 19 cases each group. The trial group was treated closed reduction rhombic distribution fixation, while control triangular...
Objective To explore the clinical efficacy of pararectus approach combined with 3D printing technique for surgical treatment partial acetabular fractures. Methods We retrospectively evaluated 33 (20 males and 13 females) patients fractures in period June 2017 to December 2018. According Judet Letournel classification: 11 cases were anterior column fracture, 10 double seven posterior half transverse, three transverse two “T” fracture. For all cases, is used print model. Pre‐bent...
Context: In cases of damaged corneal endothelium cells (CECs) the eye, transplantation cultured vascular endothelial (VECs) may be a viable method to restore transparency. Aims: To evaluate viability replacing primate CECs with allogeneic VECs. Subjects and Methods: Rhesus monkey VECs (RMVECs) were proliferating labeled bromodeoxyuridine (BrdU) in vitro. RMs experimental group (n = 6) underwent manual Descemettt membrane stripping RMVECs BrdU; those control received Descemetnt without...
To investigate the clinical effects of free superficial circumflex iliac artery (SCIA) branch perforator flap combined with full-thickness skin graft far from donor site in repairing large wounds extremities.
To investigate short-term effectiveness of robot-guided femoral neck system (FNS) combined with cannulated compression screw (CCS) fixation in treatment fracture young and middle-aged patients.
To assess the long-term effectiveness of transplantation iliac bone flap pedicled with deep circumflex vessels for treating avascular necrosis femoral head (ANFH) at Ficat stage II and III.Thirty-two cases (43 hips) ANFH underwent between October 2000 February 2006, clinical data were retrospectively reviewed. Of 32 cases, 27 male (38 hips), 5 female (5 aged 21-52 years (mean, 36.6 years); there 8 (11 hormone ANFH, 18 (23 alcoholic 6 (9 idiopathic ANFH. The disease duration ranged from 2-52...