A5079409870- Cardiac Health and Mental Health
- Cardiac Imaging and Diagnostics
- Heart Rate Variability and Autonomic Control
- Cardiovascular Health and Risk Factors
- Stress Responses and Cortisol
- Intensive Care Unit Cognitive Disorders
- Cardiovascular Health and Disease Prevention
- Acute Myocardial Infarction Research
- Health Systems, Economic Evaluations, Quality of Life
- Blood Pressure and Hypertension Studies
- Cardiovascular Disease and Adiposity
- Cardiac Arrest and Resuscitation
- Statistical Methods in Clinical Trials
- Health, psychology, and well-being
- Cardiac and Coronary Surgery Techniques
- Apelin-related biomedical research
- Healthcare professionals’ stress and burnout
- Cardiac, Anesthesia and Surgical Outcomes
- Clostridium difficile and Clostridium perfringens research
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Health disparities and outcomes
- Health Policy Implementation Science
- Resilience and Mental Health
- Hormonal Regulation and Hypertension
Vanderbilt University Medical Center
2025
Brigham and Women's Hospital
2022-2024
Emory University
2018-2023
AID Atlanta
2019-2021
Emory Clinic
2019-2021
Bridge University
2019-2021
University of Pittsburgh Medical Center
2016
University of Pittsburgh
2016
Universidade Federal do Ceará
2008-2014
Instituto Dante Pazzanese de Cardiologia
2010
Background Higher symptom levels of a variety measures emotional distress have been associated with cardiovascular disease ( CVD ), especially among women. Here, our goal was to investigate the association between composite measure psychological and incident events. Methods Results In prospective cohort study, we assessed 662 individuals (28% women; 30% blacks) stable coronary artery disease. We used score derived through summation Z-transformed scales (depression, posttraumatic stress,...
<h3>Importance</h3> Mental stress–induced myocardial ischemia is a recognized phenomenon in patients with coronary heart disease (CHD), but its clinical significance the contemporary era has not been investigated. <h3>Objective</h3> To compare association of mental or conventional adverse cardiovascular events CHD. <h3>Design, Setting, and Participants</h3> Pooled analysis 2 prospective cohort studies stable CHD from university-based hospital network Atlanta, Georgia: Stress Ischemia...
Acute mental stress can result in transient endothelial dysfunction, but the prognostic relevance of this phenomenon is unknown.To determine association between stress-induced impairment endothelium-dependent relaxation as assessed by brachial artery flow-mediated vasodilation and adverse cardiovascular outcomes among individuals with stable coronary disease.This cohort study was conducted at a university-affiliated hospital network June 2011 August 2014. A disease were included. Data...
Coronary artery disease (CAD) is a major cause of morbidity and mortality, despite important advances in our understanding this disorder, the underlying mechanisms remain under investigation. Recently, increased attention has been placed on role behavioral factors such as emotional stress CAD risk. Brain areas involved memory response, including medial prefrontal cortex, insula, parietal also have outputs to peripheral cardiovascular system. The purpose study was assess effects mental brain...
OBJECTIVE To investigate the separate and combined associations of obesity metabolic syndrome (MetS) with depression role inflammation. METHOD Depression was assessed Patient Health Questionnaire-9 (PHQ-9) defined a cutpoint ≥10. Obesity as body mass index (BMI) ≥30 kg/m2 from measured height weight. MetS based on American Heart Association consensus definition. Participants were divided into four groups: healthy normal weight (MHN), metabolically obese (MHO), unhealthy (MUN), (MUO)....
Microvascular measures of vascular dysfunction during acute mental stress may be important determinants major adverse cardiovascular events (MACE), especially among younger and middle-aged women survivors an myocardial infarction.
Background Young women with coronary artery disease ( CAD ), a group high psychosocial burden, were previously shown to have higher levels of interleukin-6 IL -6) compared men similar age. We sought examine -6 response acute stress in patients across sex and age, contrast results healthy controls other biomarkers known increase mental (monocyte chemoattractant protein-1 matrix metallopeptidase-9) limited stress-reactivity (high-sensitivity C-reactive protein). Methods Results Inflammatory...
Background: Psychological stress is a risk factor for major adverse cardiovascular events (MACE) in individuals with coronary artery disease. Certain brain regions that control both emotional states and cardiac physiology may be involved this relationship. The rostromedial prefrontal cortex (rmPFC) an important region processes regulates immune autonomic functions. Changes rmPFC activity (reactivity) informative of future MACE. Methods: Participants stable disease underwent acute mental...
Background Black patients tend to develop coronary artery disease at a younger age than other groups. Previous data on racial disparities in outcomes of myocardial infarction (MI) have been inconsistent and limited older populations. Our objective was investigate differences the outcome MI among young middle-aged role played by socioeconomic, psychosocial, clinical differences. Methods Results We studied 313 participants (65% non-Hispanic Black) <61 years old hospitalized for confirmed type...
Rationale: Excessive vasoconstriction in response to mental stress may be a potential mechanism by which acute psychological leads adverse cardiac events. Objectives: We investigated whether excessive digital during predicts cardiovascular outcomes among patients with coronary artery disease. Methods and Results: Five hundred forty-nine stable disease (age 63±9, 76% male, 29% black) underwent testing standardized public speaking stressor followed prospectively for end points. Digital pulse...
<h3>Importance</h3> Posttraumatic stress disorder (PTSD) is prevalent among patients who survived an acute coronary syndrome and associated with adverse outcomes, but the mechanisms underlying these associations are unclear. <h3>Objective</h3> To evaluate association of PTSD mental stress–induced myocardial ischemia individuals a infarction (MI). <h3>Design, Setting, Participants</h3> This cross-sectional study included 303 aged 18 to 60 years enrolled from university-affiliated network....