A5000529126- Traumatic Brain Injury Research
- Advanced Neuroimaging Techniques and Applications
- Cancer-related cognitive impairment studies
- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Neuroblastoma Research and Treatments
- Functional Brain Connectivity Studies
- Glioma Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- Gastric Cancer Management and Outcomes
- Brain Metastases and Treatment
- Radiopharmaceutical Chemistry and Applications
- Regulation of Appetite and Obesity
- Fetal and Pediatric Neurological Disorders
- Cardiovascular Effects of Exercise
- Mindfulness and Compassion Interventions
- Colorectal and Anal Carcinomas
- Trauma and Emergency Care Studies
- Colorectal Cancer Treatments and Studies
- Eating Disorders and Behaviors
- Genetic factors in colorectal cancer
- Schizophrenia research and treatment
- Medical Imaging and Pathology Studies
- Cognitive Functions and Memory
Queen Elizabeth II Health Sciences Centre
2021
Brigham and Women's Hospital
2017-2019
Harvard University
2017-2019
Toronto Rehabilitation Institute
2018-2019
University of Ottawa
2012-2018
CHU Dijon Bourgogne
2017
Centre de recherche Translationnelle en Médecine moléculaire
2017
Université de Bourgogne
2017
Université Laval
2015
McGill Genome Centre
2009
Subsequent to chemotherapy treatment, breast cancer patients often report a decline in cognitive functioning that can adversely impact many aspects of their lives. Evidence has mounted recent years indicating portion survivors who have undergone display reduced performance on objective measures relative comparison groups. Neurophysiological support for chemotherapy-related impairment been accumulating due an increase neuroimaging studies this field; however, longitudinal are limited and not...
Thalamic atrophy has been associated with exposure to repetitive head impacts (RHI) in professional fighters. The aim of this study is investigate whether or not age at first (AFE) RHI thalamic volume symptomatic former National Football League (NFL) players risk for chronic traumatic encephalopathy (CTE). Eighty-six NFL (mean = 54.9 ± 7.9 years) were included. T1-weighted data acquired on a 3T magnetic resonance imager, and volumes derived using FreeSurfer. Mood behavior, psychomotor speed,...
Worldwide, more than 22 million children and adolescents are exposed to repetitive head impacts (RHI) in soccer. Evidence indicates cumulative effects on brain structure, but it is not known whether exposure RHI affects cognitive improvement adolescents. The aim of the study was determine while heading ball soccer performance over time. group consisted a convenience sample 16 male players (mean age 15.7 ± 0.7 years). A comparison cohort 14 non-contact sports athletes 14.9 1.1 years)...
Repetitive subconcussive head impacts (RSHI) may lead to structural, functional, and metabolic alterations of the brain. While differences between males females have already been suggested following a concussion, whether there are sex exposure RSHI remains unknown. The aim this study was identify characterize RSHI.Twenty-five collegiate ice hockey players (14 11 females, 20.6 ± 2.0 years), all part Hockey Concussion Education Project (HCEP), underwent diffusion-weighted magnetic resonance...
To determine whether or not automated FreeSurfer segmentation of brain regions considered important in repetitive head trauma can be analyzed accurately without manual correction. 3 T MR neuroimaging was performed with and correction 11 former National Football League (NFL) players neurobehavioral symptoms control subjects. Automated manually-corrected volumes were compared using an intraclass correlation coefficient (ICC). Linear mixed effects regression models also used to estimate...
Understanding the relationship between chemotherapy and cognitive impairment requires information on pre-treatment variability cancer patients well-matched controls. The purpose of this study was to investigate neuroanatomical differences breast (BC) controls, prior chemotherapy,controllingfor possible confounding variables. Twenty-three female early-stage BC underwent MRI scanning after surgery but before were sex-, age- education-matched non-cancer Whole brain region interest (ROI) group...
Diffusion Tensor Imaging (DTI) studies of traumatic brain injury (TBI) have focused on alterations in microstructural features deep white matter fibers (DWM), though post-mortem demonstrated that injured axons are often observed at the gray-white interface where superficial (SWM) mediate local connectivity. To examine SWM and DWM youths with a history mild TBI relationship between attention. Using DTIDWM fractional anisotropy (FA) FA (TBI, n=63) were compared to typically developing...
Factors of increased prevalence among individuals with Black racial identity (e.g., cardiovascular disease, CVD) may influence the association between exposure to repetitive head impacts (RHI) from American football and later-life neurological outcomes. Here, we tested interaction RHI on neurobehavioral outcomes, brain volumetric measures, cerebrospinal fluid (CSF) total tau (t-tau), phosphorylated (p-tau181), Aβ1-42 in symptomatic former National Football League (NFL) players.68 male NFL...
Summary The aim of this study was to assess energy intake, resting metabolic rate ( RMR ), appetite sensations, eating behaviours and sleep duration quality in obese women resistant body weight loss when subjected a diet‐based weight‐reducing programme. A pooled cohort n = 75; aged 39 ± 8 years; mass index: 33 4 kg m −2 ) participated 12–16‐week programme targeting daily deficit 500–700 kcal d −1 . Women were classified tertiles posteriori based on the response their dietary supervision...
Of the over 1 million reported cases of traumatic brain injuries annually in USA, a sizeable proportion are characterized as mild. Although it is generally well-accepted that most people who suffer mild injury recover within to 3 months, individuals continue experience physiological, psychological, and emotional symptoms beyond expected window recovery. Depression commonly following injury; however, its course, consequences, prognostic factors remain be well understood.A systematic review...
In addition to the positive and negative symptoms, schizophrenia is associated with a variety of cognitive impairments, in particular episodic memory deficits. Functional neuroimaging studies have begun exploring potential neural correlates deficits but there are few reports structural brain abnormalities underlying impairment schizophrenia. We investigated association between morphological as revealed by cortical thickness measures performance on face recognition task. Differences regional...