A5059000422- Reading and Literacy Development
- Child and Adolescent Psychosocial and Emotional Development
- Cognitive and developmental aspects of mathematical skills
- Attention Deficit Hyperactivity Disorder
- Language Development and Disorders
- Genetics and Neurodevelopmental Disorders
- Writing and Handwriting Education
- Child Development and Digital Technology
- Maternal Mental Health During Pregnancy and Postpartum
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neuroscience and Music Perception
- Autism Spectrum Disorder Research
- Neural and Behavioral Psychology Studies
- Child and Adolescent Health
- Health and Medical Studies
- Neurobiology of Language and Bilingualism
- Eating Disorders and Behaviors
- Digital Mental Health Interventions
- Mental Health Research Topics
- Hearing Impairment and Communication
- Adolescent and Pediatric Healthcare
- Early Childhood Education and Development
- Mental Health Treatment and Access
- Infant Development and Preterm Care
- Child Nutrition and Feeding Issues
LMU Klinikum
2016-2025
Ludwig-Maximilians-Universität München
2016-2025
München Klinik
2010-2025
Klinik und Poliklinik für Kinder- und Jugendpsychiatrie
2015-2024
Klinikum Fulda
2022
National University Hospital of Iceland
2019
University of Iceland
2019
Institut für Urheber- und Medienrecht
2009-2019
Utrecht University
2019
University of Amsterdam
2019
Background: The relationship between phoneme awareness, rapid automatized naming (RAN), verbal short‐term/working memory (ST/WM) and diagnostic category is investigated in control dyslexic children, the extent to which this depends on orthographic complexity. Methods: General cognitive, phonological literacy skills were tested 1,138 1,114 children speaking six different languages spanning a large range of complexity (Finnish, Hungarian, German, Dutch, French, English). Results: Phoneme...
Comprehensive models of learning disorders have to consider both isolated that affect one domain only, as well comorbidity between disorders. However, empirical evidence on rates including all three defined by DSM-5 (deficits in reading, writing, and mathematics) is scarce. The current study assessed prevalence gender ratios for comorbid a representative sample 1633 German speaking children 3rd 4th Grade. Prevalence were analysed combined different deficit criteria, criterion normal...
Background This study examines the criterion validity of Patient Health Questionnaire 9-item (PHQ-9) and 2-item (PHQ-2) version as a depression-screening instrument for adolescents. Methods Three hundred twenty-two adolescents aged 13–16 were recruited from pediatric hospitals. Criterion PHQ-9 PHQ-2 was assessed against diagnoses any depressive disorder provided by structured diagnostic interview. Areas under receiver operating characteristics curve (AUCs) sensitivities specificities at...
The use of spoken and written language is a fundamental human capacity. Individual differences in reading- language-related skills are influenced by genetic variation, with twin-based heritability estimates 30 to 80% depending on the trait. architecture complex, heterogeneous, multifactorial, but investigations contributions single-nucleotide polymorphisms (SNPs) were thus far underpowered. We present multicohort genome-wide association study (GWAS) five traits assessed individually using...
IN order to investigate the relationship between dyslexia and central auditory processing, 19 children with spelling disability 15 controls at grades 5 6 were examined using a passive oddball paradigm. Mismatch negativity (MMN) was determined for tone speech stimuli. While there no group differences stimuli, we found significantly attenuated MMN in dyslexic This finding leads conclusion that dyslexics have specific processing deficit sensory level which could be used identify risk an early age.
An increasing number of animal studies advert to a substantial role the neuropeptide oxytocin in regulation social attachment and affiliation. Furthermore, showed anxiety stress-reduced effects oxytocin. First human confirm these findings implicate crucial behavior interactions. Thus, system might be involved impairment interaction autism spectrum disorders (ASD). The receptor gene (OXTR) represents plausible candidate for etiology ASD. To analyze whether genetic variants OXTR are associated...
Autism spectrum disorders (ASDs) are characterized by social, communication, and behavioral deficits complex genetic etiology. A recent study of 517 ASD families implicated DOCK4 single nucleotide polymorphism (SNP) association a microdeletion in an affected sibling pair.
This systematic review and meta-analysis investigated the efficacy of spelling interventions for remediation dyslexia deficits. Theoretically important moderators, such as treatment approach well orthographic sample characteristics, were also considered. Thirty-four controlled trials that evaluated in children, adolescents, adults with deficits included. Results show approaches using phonics, (graphotactic or phonological rules), morphological instruction had a moderate to high impact on...
Abstract Developmental dyslexia (DD) is a learning disorder affecting the ability to read, with heritability of 40–60%. A notable part this remains unexplained, and large genetic studies are warranted identify new susceptibility genes clarify bases dyslexia. We carried out genome-wide association study (GWAS) on 2274 cases 6272 controls, testing associations at single variant, gene, pathway level, estimating using single-nucleotide polymorphism (SNP) data. also calculated polygenic scores...
Objective: Identifying risk factors for major depression and depressive symptoms in youths could have important implications prevention efforts. This study examined the association of polygenic scores (PRSs) a broad phenotype derived from large-scale genome-wide (GWAS) adults, its interaction with childhood abuse, clinically relevant outcomes clinical epidemiological youth cohorts. Methods: The cohort comprised 279 (mean age=14.76 years [SD=2.00], 68% female) 187 healthy control subjects...
Abstract Developmental dyslexia (DD) is one of the most prevalent learning disorders, with high impact on school and psychosocial development comorbidity conditions like attention-deficit hyperactivity disorder (ADHD), depression, anxiety. DD characterized by deficits in different cognitive skills, including word reading, spelling, rapid naming, phonology. To investigate genetic basis DD, we conducted a genome-wide association study (GWAS) these skills within largest studies available, nine...
Background Children are using digital devices earlier and more frequently than they did years ago. At the same time fine motor skills spelling performance of primary school children have deteriorated over last years. There is some evidence for a relationship between performance, while role test mode in this context still unknown. Therefore, aim present study was to evaluate relation parent-reported different modes. Methods The German 3rd 4th grade (age: 8–12 years) examined, first ( N =...