A5075374525- Child and Adolescent Psychosocial and Emotional Development
- Stress Responses and Cortisol
- Attention Deficit Hyperactivity Disorder
- Child Abuse and Trauma
- Early Childhood Education and Development
- Posttraumatic Stress Disorder Research
- Identity, Memory, and Therapy
- Resilience and Mental Health
- COVID-19 and Mental Health
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Hormonal Regulation and Hypertension
- Traumatic Brain Injury Research
- Maternal Mental Health During Pregnancy and Postpartum
- Workplace Violence and Bullying
- Cognitive Abilities and Testing
- Digital Mental Health Interventions
- Autism Spectrum Disorder Research
- Sexual Assault and Victimization Studies
- Migration, Health and Trauma
- Signaling Pathways in Disease
- Counseling, Therapy, and Family Dynamics
- Circadian rhythm and melatonin
- Estrogen and related hormone effects
- Genetic Associations and Epidemiology
- Behavioral Health and Interventions
Reykjavík University
2020-2025
National University Hospital of Iceland
2019-2025
University of Iceland
2019-2024
Max Planck Society
2015-2022
Instituto de Investigaciones Psicológicas
2022
Max Planck Institute of Psychiatry
2015-2019
Ludwig-Maximilians-Universität München
2019
University of Liverpool
2019
Virginia Tech
2010-2016
Administration of Occupational Safety and Health
2016
Exposure to adverse childhood experiences (ACEs) has consistently been associated with multiple negative mental health outcomes extending into adulthood. However, given that ACEs and psychiatric disorders cluster within families, it remains be comprehensively assessed what extent familial confounding contributes associations between clinically confirmed adult disorders.
Objective: Identifying risk factors for major depression and depressive symptoms in youths could have important implications prevention efforts. This study examined the association of polygenic scores (PRSs) a broad phenotype derived from large-scale genome-wide (GWAS) adults, its interaction with childhood abuse, clinically relevant outcomes clinical epidemiological youth cohorts. Methods: The cohort comprised 279 (mean age=14.76 years [SD=2.00], 68% female) 187 healthy control subjects...
Differential effects of the coronavirus SARS-CoV-2 (COVID-19) pandemic and associated public restrictions on adolescent girls boys are emerging but have not been elucidated. This study examined gender differences across broad indicators well-being during COVID-19 in Iceland, explored potential explanations for these differences.In total, 523 youth (56.5% girls) born Iceland 2004 completed measures mental health problems (depressive symptoms, anger suicide attempts) designed this to assess...
Identification and characterisation of novel targets for treatment is a priority in the field psychiatry. FKBP5 gene with decades evidence suggesting its pathogenic role subset psychiatric patients, potential to be leveraged as therapeutic target these individuals. While it widely reported that FKBP5/FKBP51 mRNA/protein (FKBP5/1) expression impacted by disease state, risk genotype age, not known which cell types sub-anatomical areas human brain this occurs. This knowledge critical propel...
This study examined the efficacy of Collaborative & Proactive Solutions (CPS) in treating oppositional defiant disorder (ODD) youth by comparing this novel treatment to Parent Management Training (PMT), a well-established treatment, and waitlist control (WLC) group. One hundred thirty-four (ages 7–14, 61.9% male, 83.6% White) who fulfilled Diagnostic Statistical Manual Mental Disorders (4th ed.) criteria for ODD were randomized CPS, PMT, or WLC groups. was assessed with semistructured...
Background: Adverse childhood experiences (ACEs) have consistently been associated with elevated risk of multiple adverse health outcomes, yet their contribution to coping ability and psychiatric resilience in adulthood is unclear. Methods: Cross-sectional data were derived from the ongoing Stress-And-Gene-Analysis cohort, representing 30% Icelandic nationwide female population, 18–69 years. Participants current study 26,198 women on 13 ACEs measured ACE-International Questionnaire....
Abstract Background Childhood abuse and neglect have been associated with premenstrual disorders (PMDs), including syndrome (PMS) dysphoric disorder (PMDD). However, the associations of other adverse childhood experiences (ACEs) cumulative number ACEs PMDs remain to be explored. Methods To evaluate types PMDs, we conducted a cross-sectional analysis subsample menstruating women within Stress-And-Gene-Analysis (SAGA) cohort, assessed for ( N =11,973). The individual exposure 13 was evaluated...
Sexual harassment and violence in the workplace are a serious public health concern for women worldwide with substantial costs due to sick leave personnel turnover. Yet little is known about prevalence of sexual at population level, especially across work sectors. The aim this study was investigate by demographic factors sectors among Icelandic women.
Abstract Background Research on the prevalence of autism in Iceland has indicated that one possible explanation fewer cases older age groups was due to an underestimation individuals with intellectual disabilities (IDs). The present study systematically searched for adult population severe ID living city Reykjavik, Iceland. Methods Potential participants ( n = 256) were recruited through Regional Office Affairs Handicapped Reykjavik. First, a screening tool applied, followed by Childhood...
The purpose of this study is to examine the influence Attention-Deficit/Hyperactivity Disorder (ADHD), independent Oppositional Defiant (ODD), on acute treatment response, remission rates and maintenance gains at 6-month follow-up in anxious youth (ages 7–17, 76% Caucasian, 52% female) who received cognitive-behavioral therapy (CBT) alone, pharmacotherapy combination CBT or placebo pill Child/Adolescent Multimodal Study. Treatment response was defined as evaluator rated meaningful...
The objectives were twofold: (a) examine long-term treatment effects in youth receiving 1-session (OST) or educational support (EST) for a specific phobia (SP) and (b) the differential predictive moderation of attention-deficit/hyperactivity disorder (ADHD) symptoms on immediate outcomes following interventions.Eighty-three children (ages 6-15, 47% female, 89% White) with SP randomly assigned to receive OST EST. Follow up assessments occurred at 1 week, 6 months, year, 4 years. Hierarchical...
Laboratory and animal studies indicate that melatonin exerts a negative impact on breast cancer progression metastasis. These actions are both receptor-dependent -independent. Of the two transmembrane receptors identified in humans, expresses only MT1. The aim of this study was to investigate expression MT1 hormone-receptor-positive, HER2-negative invasive ductal carcinoma postmenopausal women its possible correlations with clinicopathological parameters survival. A total 118 patients...