Alexander D. Zagrebaev

ORCID: 0000-0001-5864-8991
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About
Contact & Profiles
Research Areas
  • Berberine and alkaloids research
  • Chemical synthesis and alkaloids
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Microfluidic and Capillary Electrophoresis Applications
  • Synthesis and Biological Activity
  • Alkaloids: synthesis and pharmacology
  • Organometallic Complex Synthesis and Catalysis
  • Chemical Reaction Mechanisms
  • Biosensors and Analytical Detection
  • Bone Tissue Engineering Materials
  • Biodiesel Production and Applications
  • Electrohydrodynamics and Fluid Dynamics
  • Porphyrin and Phthalocyanine Chemistry
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Titanium Alloys Microstructure and Properties
  • Gold and Silver Nanoparticles Synthesis and Applications
  • DNA and Nucleic Acid Chemistry
  • Multicomponent Synthesis of Heterocycles
  • Catalytic Processes in Materials Science
  • Catalysis and Hydrodesulfurization Studies
  • Synthesis and biological activity
  • Asymmetric Hydrogenation and Catalysis
  • 3D Printing in Biomedical Research
  • Cancer therapeutics and mechanisms
  • Synthesis and Biological Evaluation

Southern Federal University
2017-2024

We developed a microfluidic synthesis with UV-Vis diagnostics using 3D printed chip for 8,13-disubstituted berberines. This system yielded up to 30% higher product yields high antioxidant activity compared traditional batch synthesis.

10.1039/d3nj04562e article EN New Journal of Chemistry 2023-12-05

The heterocyclic core of imidazo[1,2-a]pyrimidine was formed in satisfactory yields as a result the interaction readily available 2-aminoimidazole with N-substituted maleimides or N-arylitaconimides. mechanism studied processes postulated basing on experimental data, HPLC-MS analysis reaction mixtures, and quantum chemical calculations. Molecular docking results obtained imidazo[1,2-a]pyrimidines, when compared voriconazole, drug already clinical use, suggest that they may possess antifungal...

10.3762/bjoc.20.236 article EN cc-by Beilstein Journal of Organic Chemistry 2024-11-05

Hydrosilylation of alkenes is an industrially important catalytic reaction for producing organоsilanes. This process often based on the homogeneous Pt-catalysts. Given high cost platinum and its irretrievable "scattering", new approaches that can reduce consumption are goal in modern chemistry. Heterophase (biphase) systems hydrosilylation offer additional advantages terms activity, product separation, recycling. However, large-scale synthesis heterophase conditions complicated by...

10.2139/ssrn.4829823 preprint EN 2024-01-01

Nowadays reductive hydroformylation over Rh/NR3 catalysts is of great interest to both industry and academia, however, some its aspects remain controversial or unclear, including those which might turn essential for developing new active optimization parameters. In this work, we studied in depth separately stages the process – olefins hydrogenation aldehydes, estimated role amine structure them. Also, first time, investigated catalytic system under reaction conditions by situ XAS method gain...

10.2139/ssrn.4581370 preprint EN 2023-01-01
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