Wenrui Gao

ORCID: 0000-0001-6020-3676
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About
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Research Areas
  • Plant Molecular Biology Research
  • Light effects on plants
  • Food composition and properties
  • Phytase and its Applications
  • Plant Stress Responses and Tolerance
  • Proteins in Food Systems
  • Virus-based gene therapy research
  • Legume Nitrogen Fixing Symbiosis
  • Polymer-Based Agricultural Enhancements
  • Advanced Surface Polishing Techniques
  • Photosynthetic Processes and Mechanisms
  • Seed Germination and Physiology
  • Agricultural pest management studies
  • CAR-T cell therapy research
  • Plant nutrient uptake and metabolism
  • Cancer Research and Treatments
  • Genetic and Environmental Crop Studies
  • Advanced machining processes and optimization
  • Flow Measurement and Analysis
  • Heavy Metals in Plants
  • Microbial Metabolism and Applications
  • Fluoride Effects and Removal
  • Ruminant Nutrition and Digestive Physiology
  • Energy, Environment, Economic Growth
  • Plant Gene Expression Analysis

Minjiang University
2024

National Vaccine and Serum Institute
2023-2024

Central South University
2024

Nankai University
2020-2023

Shandong Province Animal Husbandry and Veterinary Bureau
2022-2023

Chinese Academy of Sciences
2020-2021

Institute of Zoology
2020-2021

State Grid Corporation of China (China)
2017

Nanjing Agricultural University
2007-2009

Rationale: The resistance of pancreatic ductal adenocarcinoma (PDAC) to immunotherapies is caused by the immunosuppressive tumor microenvironment (TME) and dense extracellular matrix. Currently, efficacy an isolated strategy targeting stromal desmoplasia or immune cells has been met with limited success in treatment cancer. Oncolytic virus (OV) therapy can remodel TME damage either directly killing them enhancing anti-tumor response, which holds promise for PDAC. This study aimed investigate...

10.7150/thno.83495 article EN cc-by Theranostics 2023-01-01

RH6, RH8, and RH12 are previously unidentified D-body components drive the formation of D-bodies through LLPSs.

10.1126/sciadv.abc6266 article EN cc-by-nc Science Advances 2021-04-28

A novel strain, D3T, isolated from a field-soil sample obtained Anhui Province, PR China, was characterized taxonomically by using polyphasic approach. The cells were Gram-negative, yellow-pigmented rods devoid of flagella, but showing gliding motility. organism able to grow at 5–37 °C and pH 4.0–10.0. comparative 16S rRNA gene sequence analysis indicated that strain D3T is member the genus Flavobacterium, sharing highest similarity with type Flavobacterium defluvii (96.7 %). major...

10.1099/ijs.0.65536-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2008-04-01

The intestine is a complex micro-ecosystem, and its stability determines the health of animals. Different dietary nutritional levels affect intestinal microbiota health. In this study, energy protein in diet goats were changed, body weight was measured every 15 days. late feeding period, 16 S rRNA sequencing technology used to detect content microorganisms. A meteorological chromatograph volatile fatty acids cecum colon goats. stage, reducing level significantly reduced lamb (p < 0.05)....

10.3390/microorganisms10122322 article EN cc-by Microorganisms 2022-11-24

Oncolytic herpes simplex virus (oHSV) is a type of that selectively targets and kills cancer cells, leaving normal cells unharmed. Accurate viral titer great importance for the production application oHSV products. Droplet digital PCR (ddPCR) known having good reproducibility, not requiring standard curve, being affected by inhibitors, precise even in detection low copies. In present study, we developed droplet assay quantification HSV-1 applied it production. The established ddPCR showed...

10.3390/v15010178 article EN cc-by Viruses 2023-01-07

Small RNA (sRNA) turnover is a key but poorly understood mechanism that determines the homeostasis of sRNAs. Animal XRN genes contribute degradation sRNAs, AtXRN2 and AtXRN3 also pri-miRNA processing miRNA loop in plants. However, possible functions plant sRNA are far from known. Here, we find AtXRN4 contributes sRNAs Arabidopsis thaliana mainly by sRNA-seq, qRT-PCR Northern blot. The mutation alters profile accumulation 21 nt was increased. Some miRNA*s levels significantly increased xrn4...

10.3390/plants9030362 article EN cc-by Plants 2020-03-13

Seed germination is an important phase transitional period of angiosperm plants during which seeds are highly sensitive to different environmental conditions. Although seed under the regulation salicylic acid (SA) and other hormones, molecular mechanism underlying these regulations remains mysterious. In this study, we determined expression SA methyl esterase (MES) family genes germination. We found that MES7 decreases significantly in imbibed seeds, dysfunction content. Furthermore, reduces...

10.3390/plants10050903 article EN cc-by Plants 2021-04-30

<title>Abstract</title> Seed germination is an important phase transitional period of angiosperm plants and sensitive to environment condition. Although seed under the regulation salicylic acid (SA) other hormones, molecular mechanism underlying these regulations remains mysterious. In this study, we determined expression SA methyl esterase (MES) family genes during germination. We found that MES7 decreases significantly in imbibed seeds, dysfunction content. Furthermore, reduces promotes...

10.21203/rs.3.rs-231081/v1 preprint EN cc-by Research Square (Research Square) 2021-02-17

ABSTRACT The physicochemical and functional properties of protein isolates from two Chinese chickpea cultivars were investigated compared with those SPI. GCPI has the lightest, reddest, most yellow highest chroma. SHF Ho three significantly different (P < 0.05). Significant differences 0.05) in EAI, FC, FS LGC observed between isolates, whose inferior to Most textural heated gels similar also SPI gel. PRACTICAL APPLICATIONS Chickpea is third widely grown grain legume crop world after bean...

10.1111/j.1745-4549.2008.00359.x article EN Journal of Food Processing and Preservation 2009-12-01

This article aims to study the comprehensive impact of ESG (Environmental, Social, and Governance) indicators on supply chain sustainability, economic growth, policy making. Through analysis relevant research cases, this finds that application has positive effects sustainability chains also important growth In terms introduction prompts companies adopt more environmentally friendly, socially responsible, transparent business practices, improving overall chains. help stimulate innovation...

10.54097/10a2tn89 article EN cc-by-nc Highlights in Business Economics and Management 2024-03-21

In this study, a novel type of diamond grinding wheel with linear cooling channels (GWLCC) is proposed, and an innovative manufacturing process employed to develop new wheel. Grinding experiments conducted on four types hard brittle materials demonstrate that the performance GWLCC better than conventional dense wheels. Furthermore, was further investigated by comparing abrasive ratio working current under various parameters. The results indicate efficiency positively correlated rotating...

10.1038/s41598-024-80250-3 article EN cc-by-nc-nd Scientific Reports 2024-11-22

Background: Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant tumor with notably poor response to therapy due its immunosuppressive microenvironment (TME) and intrinsic drug resistance. The oncolytic virus (OV) represents promising therapeutic strategy capable of transforming the “cold” immunological profile PDAC tumors “hot” one by reshaping TME. 4-1BB (CD137), crucial member necrosis factor receptor superfamily, plays significant role in T-cell activation function. Methods: In...

10.3390/vaccines12121309 article EN cc-by Vaccines 2024-11-22

Regulation of gene expression at the level transcription controls many crucial biological processes including growth and development, stress response, signal transduction disease resistance.A number factors, such as C 2 H zinc finger protein, are required factors play an important role in transcription.Chickpea (Cicer arietinum L.) is third legume crop gown mainly arid semi-arid regions world.Due to its taxonomic proximity with model genome Medicago truncatula ability grow soil relatively...

10.3724/sp.j.1006.2009.02180 article EN ACTA AGRONOMICA SINICA 2009-12-30

In order to evaluate the heavy metal potential pollution of soil and medicinal materials in main producing area Phellodendron amurense, we collected 32 samples herb from northeast north China covering four provinces. this study, detection contents was conducted by ICP emission spectroscopy atomic fluorescence spectrometry. The results showed that all areas Ph amurense generally reached national standard. As, Hg, Cr, Cd, Pb Cu content met requirtment standard except Hg exceeding slight a few...

10.4268/cjcmm20160304 article EN China Journal of Chinese Materia Medica 2016-02-01
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