A5061991548- Gastroesophageal reflux and treatments
- Gastrointestinal motility and disorders
- Pelvic floor disorders treatments
- Esophageal and GI Pathology
- Eosinophilic Esophagitis
- Pancreatic and Hepatic Oncology Research
- Helicobacter pylori-related gastroenterology studies
- Anorectal Disease Treatments and Outcomes
- Colorectal Cancer Screening and Detection
- Dysphagia Assessment and Management
- Gallbladder and Bile Duct Disorders
- Gastric Cancer Management and Outcomes
- Diverticular Disease and Complications
- Congenital gastrointestinal and neural anomalies
- Diet and metabolism studies
- Inflammatory Bowel Disease
- Pancreatitis Pathology and Treatment
- Clinical Nutrition and Gastroenterology
- Genetic factors in colorectal cancer
- Tracheal and airway disorders
- Biliary and Gastrointestinal Fistulas
- Pediatric Hepatobiliary Diseases and Treatments
- Colorectal Cancer Surgical Treatments
- Hernia repair and management
- Advances in Oncology and Radiotherapy
University Hospital of Basel
2022-2025
University of Zurich
2013-2023
University Hospital of Zurich
2013-2023
St. Claraspital
2018-2023
Hirslanden Klinik St. Anna
2021-2023
University of Basel
2023
Stadtspital Waid
2020-2022
Triemli Hospital
2014-2018
Queen Mary University of London
2016-2018
Friedrich-Alexander-Universität Erlangen-Nürnberg
2017
This manuscript summarizes consensus reached by the International Anorectal Physiology Working Group (IAPWG) for performance, terminology used, and interpretation of anorectal function testing including manometry (focused on high-resolution manometry), rectal sensory test, balloon expulsion test. Based these measurements, a classification system disorders is proposed.Twenty-nine working group members (clinicians/academics in field gastroenterology, coloproctology, gastrointestinal...
Ano-rectal manometry (ARM) is the most commonly performed investigation for assessment of anorectal dysfunction. Its use supported by expert consensus documents and international guidelines. Variation in technology, data acquisition, analysis affect results clinical interpretation. This study examined variation ARM between institutions to establish status current practice.A 50-item web-based questionnaire assessing interpretation was distributed International Anorectal Physiology Working...
Extraintestinal manifestations (EIMs) in patients with inflammatory bowel disease (IBD) are frequently observed. Little is known about the efficacy of anti-tumor necrosis factor (TNF) EIM management. We assessed effect 3 anti-TNF agents (infliximab, adalimumab, and certolizumab pegol) on evolution.Data 1249 from Swiss IBD Cohort Study (SIBDCS) were analyzed. All EIMs diagnosed by relevant specialists. Response was classified into improvement, stable disease, clinical worsening based...
Gallstones and kidney stones are known complications of inflammatory bowel diseases (IBD). Risk factors have been insufficiently studied explanatory studies date back up to 30 years. It remains unclear, whether improved treatment options also influenced risk for these complications.Identifying gallstones in IBD patients.Using data from the Swiss Inflammatory Bowel Disease Cohort Study we assessed associations characteristics with univariate multivariate logistic regression analyses.Out 2323...
Abstract Background Measurements of anorectal function using high‐resolution manometry ( HR ‐ ARM ) and rectal barostat technology provide more reliable results than standard with an elastic balloon; however, have not been compared to protocols are impractical in routine clinical practice. The aim this study was validate against a novel Rapid Barostat Bag RBB measurement balloon measurements function. Methods Twenty‐six healthy volunteers (15 female, 11 male, 19–52 years) were studied. anal...
Quarantine with social distancing has reduced transmission of COVID-19; however, fear the disease and these remedial measures cause anxiety stress. It is not known whether events have impacted prevalence gastrointestinal (GI) symptoms disorders brain-gut interaction (DGBI).An online platform evaluated GI during COVID-19 pandemic. Data collection utilized validated questionnaires was fully anonymized. Findings were compared identical data acquired in 2019. The association results stress...
Abstract Background Guidelines recommend instruction and motivation during anorectal manometry; however, its impact on findings has not been reported. This study assessed the effects of standard versus enhanced verbal feedback results manometry. Methods High‐resolution manometry was performed by a solid‐state catheter with 10 circumferential sensors at 6 mm separation across anal canal two rectal sensors. Measurements were acquired first then feedback. On both occasions, squeeze pressure...
High-resolution esophageal manometry (HRM) is a recent development used in the evaluation of function. Our aim was to assess inter-observer agreement for diagnosis motility disorders using this technology. Practitioners registered on HRM Working Group website were invited review and classify (i) 147 individual water swallows (ii) 40 diagnostic studies comprising 10 drop-down menu that followed Chicago Classification system. Data presented standardized format with pressure contours without...
Abstract Background Advances in clinical measurement of esophageal motility and function have improved the assessment swallowing disorders reflux symptoms. Variation data acquisition, analysis, reporting exists impacts on diagnosis management. Aims Methods This study examined variation manometry methodology between institutions to establish status current practice. A structured survey was distributed through international NGM societies using an Internet‐based platform. Questions explored...
Summary Background Standard high‐resolution manometry (HRM) protocols are based on 10 single water swallows acquired in the supine position. Aims To assess impact of position, rapid drink challenge and solid test meal diagnosis oesophageal motility disorders. Methods Seventy‐two healthy volunteers (20‐76 years) 366 consecutive patients (18‐90 completed HRM with upright positions. Rapid was performed twice, before after meal. Diagnosis position (Chicago Classification v3.0) compared results...
Main Recommendations Peroral endoscopic myotomy (POEM) is an advanced procedure that has become a first-line treatment for esophageal achalasia and other spastic disorders. Structured training essential to optimize the outcomes of this technique. The European Society Gastrointestinal Endoscopy (ESGE) recognized need formalize enhance in POEM. This Position Statement presents results systematic review literature formal Delphi process, providing recommendations optimal program POEM aims...
Objectives: Non-exposed endoscopic full-thickness resection (EFTR) using a dedicated device (FTRD) can be used to perform en bloc of subepithelial lesions throughout the gastrointestinal tract. Here we aim evaluate safety and efficacy EFTR for management duodenal neuroendocrine tumors (dNET). Methods: International multicenter retrospective study assisted dNET. Study outcomes included rates technical success, R0 resection, adverse events (AE). Results: 171 patients were across 35 centers....
Main Recommendation 1 A POEM equipment checklist should be used before commencing the procedure to ensure availability and proper functioning of all necessary materials. 2 thorough esophageal cleansing mucosal incision is mandatory. There no residual dietary liquid or food in lumen. 3 Use at least 5–10 mL lifting agent, which injected using a needle desired point where mucosotomy will commence. 4 To create mucosotomy, first made site previous injection with fewest possible taps on...
Introduction: Biliary stenting is commonly used for managing bile duct conditions, with stent migration occurring in up to 21% of cases. Colonic perforation from rare, typically managed surgically or conventional endoscopic clips. The use over-the-scope clips (OTSCs) such perforations less documented. Case Presentation: An 89-year-old multimorbid woman presented abdominal pain and new-onset constipation. Imaging revealed a migrated biliary causing sigmoid colon perforation. One year earlier,...