A5021000774- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Diagnosis and treatment of tuberculosis
- Pneumonia and Respiratory Infections
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Respiratory and Cough-Related Research
- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Asthma and respiratory diseases
- Remote Sensing and Land Use
- Pediatric health and respiratory diseases
- SARS-CoV-2 and COVID-19 Research
- Nosocomial Infections in ICU
- Health and Wellbeing Research
- Nutrition and Health in Aging
- Spacecraft and Cryogenic Technologies
- Pleural and Pulmonary Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Vaccine Coverage and Hesitancy
- Infectious Diseases and Tuberculosis
- Tracheal and airway disorders
- Acute Kidney Injury Research
Inje University Ilsan Paik Hospital
2015-2025
Inje University
2008-2023
Catholic University of Korea
2020
Chungnam National University Hospital
2020
National University College
2020
Chungbuk National University
2020
New Generation University College
2020
Pulmonary and Critical Care Associates
2017
Korea Institute of Geoscience and Mineral Resources
2011-2016
Inje University Seoul Paik Hospital
2012
Rationale: Few large-scale studies have investigated multidrug-resistant tuberculosis (MDR-TB) treatment outcomes relative to drug-resistance patterns.Objectives: To assess the impact of additional drug resistances on and long-term survival in a large HIV-negative MDR-TB cohort.Methods: Treatment patients with newly diagnosed or retreated 2000 2002 were retrospectively analyzed based patterns after 5–8 years follow-up.Measurements Main Results: Of 1,407 MDR-TB, 75 (5.3%) had extensively...
Hand grip strength (HGS) is a simple way of predicting the risk cardiovascular disease and all-cause mortality in general population. However, practical significance patients with COPD uncertain. The aim this study was to compare HGS between subjects without evaluate its clinical relevance by using national survey.Data were collected from Korean National Health Nutrition Examination Survey. included 421 adults 2,542 controls who completed questionnaires, spirometry, test. compared COPD,...
Abstract Disparities exist between sexes regarding tuberculosis (TB) incidence, as well disease severity and outcome. Using a nationwide TB registry database, we explored the impact of sex age on extrapulmonary (EPTB) among all enrolled patients by (1) calculating female proportion for every category according to TB-affected locations, (2) proportions EPTB stratified age, (3) conducting multivariable analysis examine likelihood, (4) assessing odds compared male reference in category....
Rationale: The insulin-like growth factor-I (IGF-I) pathway is an important determinant of survival and proliferation in many cells. However, little known about the role IGF-I lung injury. We previously showed elevated levels bronchoalveolar lavage fluid from patients with acute respiratory distress syndrome. Furthermore, immunodepletion IGF syndrome increased fibroblast apoptosis.Objectives: examined effect blockade type 1 tyrosine kinase receptor (IGF-IR) a murine model bleomycin-induced...
To determine the impact of sarcopenia and obesity on pulmonary function quality life (QOL) in chronic obstructive disease (COPD) patients.Data were obtained from Korea National Health Nutrition Examination Survey, including data health interviews, examinations, nutritional questionnaires, laboratory findings. Laboratory included assessment dual energy X-ray absorptiometry results. Sarcopenia was measured by absorptiometry, defined body mass index. Male COPD patients then classified into 4...
The national Public-Private Mix (PPM) tuberculosis (TB) control project provides for the comprehensive management of TB patients at private hospitals in South Korea. Surveillance and monitoring under PPM are essential toward achieving elimination goals.TB is a nationally notifiable disease Korea monitored using surveillance system. Centers Disease Control Prevention quarterly generates indicators management, used to evaluate activities by central steering committee project. Based on...
Background Chronic obstructive pulmonary disease (COPD), is a chronic inflammatory disorder. We evaluated whether white blood cell (WBC) count, associated with the severity of COPD, independent other conditions, such as metabolic syndrome. Methods The WBC counts were compared between 1227 COPD patients and 8679 non-COPD adults older than 40. relationships lung function, symptoms score in patients, determined, using general linear regression analyses. Results count was negatively forced vital...
BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic caused disruptions to healthcare systems and endangered the control prevention of tuberculosis (TB). We investigated nationwide effects COVID-19 on national Public-Private Mix (PPM) TB project in Korea, using monitoring indicators from Korean PPM database. METHODS: database includes data patients registered at hospitals throughout country. Data six for active cases updated between July June 2020 were collected. each cohort country...
Fully vaccinated people remain at risk of Coronavirus Disease 2019 (COVID-19). We examined association between prior vaccination and clinical outcomes in patients with COVID-19. Overall, 387 mild-to-severe COVID-19 were enrolled. Patients considered fully least 14, 7, 14 days after receiving the second dose ChAdOx1 nCoV-19 or mRNA-1273, BNT162b2, single Ad26.COV2.S, respectively. The primary (risk pneumonia, requirement supplemental oxygen, progression to respiratory failure) compared...
The aim of this study is to extract landslide-related factors from remote-sensing data, such as Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) satellite imagery, examine their applicability landslide susceptibility near Boun, Korea, using a geographic information system (GIS). Landslide was mapped interpretation aerial photographs field surveying. Factors that influence occurrence were extracted ASTER imagery. slope, aspect curvature calculated the digital elevation...
Although the incidence of tuberculosis (TB) has decreased in South Korea, mortality rate remains high. TB is a key indicator for control interventions. The purpose this study was to assess early and TB-related during anti-TB treatment describe associated clinical characteristics.A multicenter cross-sectional performed across Korea. Patients with pulmonary who died whose records were submitted national surveillance system between 2015 2017 enrolled. All deaths categorized based on cause...
The coronavirus disease 2019 (COVID-19) pandemic caused disruptions to healthcare systems, consequently endangering tuberculosis (TB) control. We investigated delays in TB treatment among notified patients during the first wave of COVID-19 Korea. systemically collected and analyzed data from Korea cohort database January May 2020. Groups were categorized as 'before-pandemic' 'during-pandemic' based on notification period. Presentation delay was defined period between initial onset symptoms...
Screening patients with asymptomatic active tuberculosis (TB) is crucial as they can transmit the disease. Identifying risk factors for transmission essential targeted screening. Understanding how infectiousness of TB affects disease outcomes developing strategies to control spread. We analyzed national Korean cohort data determine associated and clinical in pulmonary TB. The primary outcome was a factor transmission, while secondary mortality stratified by risk. Among 20 455 TB, 7434...
The Leicester Cough Questionnaire (LCQ) is a validated tool for assessing cough-related impairments across three domains: physical, psychological, and social. This study explored the interrelationships among social domains of chronic cough using LCQ. Adult patients with from 16 respiratory centers who completed LCQ diagnostic workup were retrospectively analyzed. Spearman's rank correlation analysis was conducted to evaluate correlations items domains. Causal mediation decomposed total...
Pulmonary rehabilitation is a multidisciplinary program of care for patients with chronic respiratory impairment that individually tailored and designed to optimize physical social performance autonomy. It can reduce symptoms, decrease disability, increase participation in activities, improve the overall quality life individuals disease. consists exercise training, patient family education, psychosocial behavioral intervention. The training should be performed at least five times per week 30...
Abstract Background Subclinical tuberculosis (TB) is a potential target for public health intervention because its early identification may reduce TB transmission. We aimed to describe the clinical and laboratory findings of subclinical disease among pulmonary patients compared treatment outcomes active diseases. Methods In this prospective cohort study, we enrolled adult aged ≥ 19 years with between 2016 2018. was defined as radiographic or microbiologic test results consistent without...
The Government of South Korea launched a national preemptive latent tuberculosis infection (LTBI) screening program in 2016, including more than 1. 6 million population congregate settings. objective this study was to analyze LTBI prevalence and its risk factors each setting. Additionally, the proportion pool covered by current strategy investigated. Database for results interferon gamma release assay (IGRA), X-ray, baseline demographic information linked with National Health Information...
Background Chronic cough is a heterogeneous disease with various aetiologies that are difficult to determine. Our study aimed categorise the phenotypes of chronic cough. Methods Adult patients were assessed based on characteristics and severity their using COugh Assessment Test (COAT) Korean version Leicester Cough Questionnaire. A cluster analysis was performed K-prototype, variables be included determined correlation network. Results In total, 255 participants in analysis. Based network,...
Assessing the illness perception of patients with tuberculosis (TB) could improve our understanding their beliefs about disease and help address problems in health-seeking behavior.We assessed pulmonary TB association patients' demographic, socioeconomic, clinical features.Adult who were newly diagnosed at three tertiary hospitals South Korea included from November 2016 September 2018. Participants' was using Brief Illness Perception Questionnaire (BIPQ) start anti-TB treatment.In total, 390...
Hospital-acquired pneumonia (HAP) and ventilator-associated (VAP) are significant public health issues in the world, but epidemiological data pertaining to HAP/VAP is limited Korea. The objective of this study was investigate characteristics, management, clinical outcomes This a multicenter retrospective cohort study. In total, 206,372 adult patients, who were hospitalized at one 13 participating tertiary hospitals Korea, screened for eligibility during six-month period. Among them, we...
Vaccination is an important strategy for controlling the coronavirus disease 2019 (COVID-19) pandemic. We conducted a web-based cross-sectional survey based on Google Forms to collect data adverse events (AEs) after first dose of ChAdOx1 nCoV-19 vaccine healthcare workers (HCWs). Among 1,676 vaccinated HCWs, 59.5% (998/1,676) responded survey. In total, 809 (81.1%) respondents reported experiencing AEs. There were no serious AEs, such as anaphylaxis. The most common AE was pain at injection...
Abstract Tuberculosis (TB) has a heterogeneous phenotype, which makes it challenging to diagnose. Our study aimed identify TB phenotypes through cluster analysis and compare their initial symptomatic, microbiological radiographic characteristics. We systemically collected data of notified patients in Korea constructed prospective, observational cohort database. Cluster was performed using K-means clustering, the variables be included were determined by correlation network. A total 4,370...