A5024260821- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Allergic Rhinitis and Sensitization
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Dermatology and Skin Diseases
- Urticaria and Related Conditions
- Food Allergy and Anaphylaxis Research
- Eosinophilic Esophagitis
- Pediatric health and respiratory diseases
- Pancreatic and Hepatic Oncology Research
- Drug-Induced Adverse Reactions
- Inhalation and Respiratory Drug Delivery
- Contact Dermatitis and Allergies
- IL-33, ST2, and ILC Pathways
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Autoimmune Bullous Skin Diseases
- Cancer Genomics and Diagnostics
- Eosinophilic Disorders and Syndromes
- Neuroendocrine Tumor Research Advances
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Voice and Speech Disorders
- Gallbladder and Bile Duct Disorders
- Immunodeficiency and Autoimmune Disorders
- Hepatitis B Virus Studies
- Air Quality and Health Impacts
Kangwon National University
2016-2025
Kangwon National University Hospital
2014-2025
University of Ulsan
2019-2021
Ulsan College
2019-2021
Asan Medical Center
2011-2021
Kangdong Sacred Heart Hospital
2014-2015
Hallym University
2014-2015
Seoul National University
2008-2013
Seoul National University Hospital
2008-2013
Seoul National University Bundang Hospital
2012
Exposure to low levels of volatile organic compounds (VOCs) in ordinary life is suspected be related oxidative stress and decreased lung function. This study evaluated whether exposure ambient VOCs indoor air affects airway inflammation.Thirty-four subjects from the hospital that had moved a new building were enrolled. Symptoms sick syndrome, pulmonary function tests, fractional exhaled nitric oxide (FeNO) evaluated, random urine samples collected 1 week before after move. Urine analyzed for...
Recent evidence suggests that cough hypersensitivity may be a common feature of chronic in adults. However, the clinical relevance remains unclear. This study evaluated cough-related symptom profile and impact adults with cough.This cross-sectional multi-center compared laryngeal sensations triggers patients unexplained following investigations unselected newly referred for cough. A structured questionnaire was used to assess abnormal triggers. Patients were also using Leicester Cough...
ABSTRACT Background and objective: Reactivation of hepatitis B virus (HBV) is thought to be associated with immunosuppressive treatments, but insufficient information available on the effect corticosteroids. The aim this study was evaluate risk HBV reactivation in surface antigen‐seropositive patients asthma or COPD, who were treated systemic corticosteroids (SCS) addition inhaled (ICS). Methods: Patients COPD ( n = 198), had been ICS, identified retrospectively. To additional effects SCS,...
Purpose: Although mild to moderate asthma is much more common, the morbidity and mortality of severe are higher.This study was performed identify analyze clinical characteristics in Korea.Methods: We registered patients with refractory into Severe Asthma Registry supported by Work Group Korean Academy Asthma, Allergy Clinical Immunology.Patients were enrolled since 2010 from 15 university hospitals nationwide Korea.Severe defined according modified European Respiratory Society/American...
sal congestion, the most common symptom, and long-term use can lead to weight gain in some patients.Thus, patients who do not want receive such medication often seek complementary alternative therapies effects of which have yet been verified.Ginseng has long used as an herbal throughout East Asia, including Korea, is a member scientific family Araliaceae, genus Panax.Of species ginseng,
There are no specific tools for measurement of the severity chronic cough in Korea. We developed a Korean version Leicester Cough Questionnaire (LCQ) and tested its scaling clinical properties.The LCQ was adapted conditions following forward-backward translation procedure. All patients referred to clinics at 5 university hospitals between May 2011 October 2013 completed 2 questionnaires, Short-Form 36 (SF-36), upon presentation Global Rating Change (GRC) follow-up visits after or 4 weeks....
Despite the high burden and frequency of urticaria, its epidemiology is not well known. We investigated various type urticaria in Korea changes annual prevalence over 5 years.We used data from 2010 to 2014 Health Insurance Review Assessment database, which covers claims 97.0% South Korean population. Patients aged > 10 years old were included this study. The presence was identified on physician-certified diagnoses using International Classification Diseases 10th Revision (ICD-10) codes that...
Severe asthma is associated with high morbidity and healthcare utilization; however, treatment options for these patients are limited. This study aimed to determine the therapeutic effects of biologics in clinical practice. multicenter, retrospective cohort included 136 who received at least 4 months between September 2017 July 2022 25 medical centers affiliated Korean Asthma Registry (KoSAR). The evaluated effects, including acute exacerbation rates, maintenance oral corticosteroid dosages,...
Abstract Background While the clinical characteristics and outcomes of asthma‐chronic obstructive pulmonary disease (COPD) overlap (ACO) have been frequently compared with those COPD or asthma, prevalence features ACO in patients severe asthma are unclear. Objectives Evaluation using Korean registry. Methods At time registration, was determined by attending specialists. Patients were classified into non‐ACO groups, demographic these two groups compared. Results Of 482 23.7% had ACO. group...
Rosacea is a chronic inflammatory skin disease. Recent studies have indicated its impacts on systemic health beyond dermatological symptoms. The gut-skin axis theory, which explores the interaction between gastrointestinal and health, may explain influence of rosacea disorders. This study investigates potential link risk developing irritable bowel syndrome (IBS) using Korean National Health Insurance Service-National Sample Cohort (NHIS-NSC). Data for this retrospective cohort were sourced...
Background The relationship between pre-treatment levels of blood eosinophil count (BEC), fractional exhaled nitric oxide (FeNO), and sputum eosinophils (Sp-EOS) treatment response to monoclonal antibodies (mAbs) in severe eosinophilic asthma (SEA) remain unclear. Objective We evaluated BEC, FeNO, Sp-EOS, their combinations as predictors responses patients with SEA undergoing anti-IL5/IL5Rα or anti-IL-4Rα antibody therapies. Methods study included 153 adult (59 94 anti-IL4Rα users). Logistic...
Mepolizumab, an interleukin-5 antagonist, is globally recognized for its efficacy in randomized controlled trials the treatment of severe eosinophilic asthma. The present study explored real-world effectiveness and safety a Korean cohort, filling critical gap current research. This multi-center retrospective used data from Severe Asthma Registry, involving 67 patients treated with mepolizumab uncontrolled asthma between September 2017 July 2022. We assessed effects on acute exacerbations,...
The Leicester Cough Questionnaire (LCQ) is a validated tool for assessing cough-related impairments across three domains: physical, psychological, and social. This study explored the interrelationships among social domains of chronic cough using LCQ. Adult patients with from 16 respiratory centers who completed LCQ diagnostic workup were retrospectively analyzed. Spearman's rank correlation analysis was conducted to evaluate correlations items domains. Causal mediation decomposed total...
<b><i>Background:</i></b> Obesity is a risk factor for asthma in the general population, but effect of obesity on airway hyperresponsiveness (AFHR) or inflammation not clear. This study evaluated relationship between and asthma, assessing aspects symptoms, AHR, severity. <b><i>Methods:</i></b> In total, 852 patients with diagnosed by specialists based AHR as confirmed methacholine bronchial provocation test, were enrolled from Cohort Reality...
Purpose: This retrospective study was conducted to estimate the effects of climate factors and air pollution on asthma exacerbations using a casecrossover analysis.Methods: Patients who visited emergency department (ED) 2 university hospitals in Chuncheon for from January 1, 2006, December 31, 2011, were enrolled.Daily average data meteorological (temperature, daily temperature range, relative humidity, wind speed, atmospheric pressure, presence rain, solar irradiation, fog) levels gaseous...
Background/Aims: Using a nationwide cohort, we investigated the cancer risk in Korean patients with gout.Methods: Data were obtained from National Health Insurance Service Database. Patients gout defined as those aged ≥ 20 years who diagnosed and received anti-gout medication (allopurinol, colchicine, benzbromarone) between 2008 2010. nail disorders randomly assigned to control group (1:1 ratio) after frequency matching for age sex. Cancer incidence was then 2012 2018. Cox proportional...