A5100358489- Nanoplatforms for cancer theranostics
- Advanced Photocatalysis Techniques
- Carbon Dioxide Capture Technologies
- Graphene and Nanomaterials Applications
- Membrane Separation and Gas Transport
- Nanoparticle-Based Drug Delivery
- Bone Tissue Engineering Materials
- Luminescence and Fluorescent Materials
- Advanced Nanomaterials in Catalysis
- Electrocatalysts for Energy Conversion
- Bat Biology and Ecology Studies
- Phase Equilibria and Thermodynamics
- Gas Sensing Nanomaterials and Sensors
- RNA modifications and cancer
- Nonlinear Optical Materials Research
- Metal-Organic Frameworks: Synthesis and Applications
- Covalent Organic Framework Applications
- Cancer Immunotherapy and Biomarkers
- Magnesium Alloys: Properties and Applications
- Advanced biosensing and bioanalysis techniques
- Catalytic Processes in Materials Science
- MXene and MAX Phase Materials
- Carbon Nanotubes in Composites
- Electrospun Nanofibers in Biomedical Applications
- Nanoparticles: synthesis and applications
Huaiyin Institute of Technology
2019-2025
Hebei Medical University
2017-2025
Henan Normal University
2021-2025
First Affiliated Hospital of Hebei Medical University
2024-2025
Huazhong University of Science and Technology
2023-2025
Anhui University of Traditional Chinese Medicine
2025
Qilu University of Technology
2025
Shandong Academy of Sciences
2025
University of Jinan
2022-2024
Ludong University
2022-2024
Alzheimer's disease (AD) is a neurodegenerative characterized by progressive decline in cognitive ability. Exosomes derived from bone-marrow mesenchymal stem cells (BMSC-exos) are extracellular vesicles that can execute the function of (BMSCs). Given versatile therapeutic potential BMSC and BMSC-exos, especially their neuroprotective effect, aim this study was to investigate effect BMSC-exos on AD-like behavioral dysfunction mice explore possible molecular mechanism.
In this paper, we develop an environmentally friendly, one-pot strategy toward rapid preparation of Ag nanoparticle-decorated reducd graphene oxide (AgNPs/rGO) composites by heating the mixture GO and AgNO(3) aqueous solution in presence sodium hydroxide at 80 °C under stirring. The reaction was accomplished within a short period 10 min without extra reducing agent. As-synthesized AgNPs/rGO have been successfully applied photocurrent generation visible spectral region.
Although ultrasmall metal nanoparticles (NPs) have been used as radiosensitizers to enhance the local damage tumor tissues while reducing injury surrounding organs, their rapid clearance from circulatory system and presence of hypoxia within continue hamper further application in radiotherapy (RT). In this study, we report a size tunable nanocluster bomb with initial approximately 33 nm featuring long half-life during blood circulation destructed release small microenvironment-targeting NPs...
Magnesium alloy is considered as one of the ideal cardiovascular stent materials owing to its good mechanical properties and biodegradability. However, in vivo rapid degradation rate insufficient biocompatibility restrict clinical applications. In this study, magnesium (AZ31B) was modified by combining surface chemical treatment in-situ self-assembly 16-phosphonyl-hexadecanoic acid, followed immobilization chitosan-functionalized graphene oxide (GOCS). Heparin (Hep) GOCS were alternatively...
Abstract The symptoms of vaginal candidiasis exacerbate in the second half menstrual cycle premenopausal women when serum estradiol level is elevated. Estradiol has been shown to inhibit Th17 differentiation and production antifungal IL-17 cytokines. However, little known about mechanisms. In present study, we used mouse splenocytes found that inhibited through downregulation Rorγt mRNA protein expression. activated estrogen receptor (ER)α recruit repressor activity (REA) form ERα/REA...
Lung cancer is a kind of malignancy with high morbidity and mortality worldwide. Paclitaxel (PTX) the main treatment for non-small cell lung (NSCLC), resistance to PTX seriously affects survival patients. However, underlying mechanism potential reversing strategy need be further explored.We identified ALDH2 as resistance-related gene using microarray analysis. Subsequently, series functional analysis in lines, patient samples xenograft models were performed explore role, clinical...
Wet clutch, as a transmission system, plays critical role in many mechanical applications, such those vehicles, ships, and helicopters. The performance of wet clutches significantly affects the overall performance. Since their inception, multi-plate have been focal point clutch research. With widespread application clutches, research this area has become increasingly extensive in-depth. Researchers investigated thermal characteristics frictional pairs during engagement, by noting sharp...
Recent progress in developing highly efficient nonlinear optical dendrimers and polymers for high-performance electro-optic (EO) devices has been reviewed. Our efforts are focused on using nanoscale architectural control to tailor the size, shape, conformation, functionality of NLO chromophores macromolecules studying their effects poling efficiency. The structures these materials vary from a 3-D-shaped dendritic chromophore, multifunctional with center core connected cross-linkable...
Abstract The contributions of interleukin (IL)-17 to cancer remain unclear and somewhat controversial. We took a genetic approach explore its role in prostate cancers by interbreeding IL-17 receptor C (IL-17RC)–deficient mice with that are conditionally mutant for PTEN, one established preclinical model cancer. Mice were IL-17RC–deficient (IL-17RC−) displayed prostates smaller than maintained IL-17RC expression (IL-17RC+). In addition, IL-17RC− developed reduced number invasive...
Interleukin-17 (IL-17) is a proinflammatory cytokine that plays important roles in inflammation, autoimmunity, and cancer. The purpose of this study was to determine if IL-17 indirectly regulates macrophage differentiation through up-regulation cyclooxygenase-2 (COX-2) expression the cancer cell lines.Human cervical HeLa, human lung A549, mouse prostate Myc-CaP/CR lines were treated with recombinant IL-17; Western blot analysis, enzyme-linked immunosorbent assay, quantitative real-time...
Homeobox (HOX) transcript antisense RNA (HOTAIR), as a long intergenic noncoding (lincRNA), is known to be overexpressed in several cancers. However, the role of HOTAIR Parkinson's disease (PD) remains unclear. A mouse model PD was developed by intraperitoneal injection MPTP (N-methyl-4-phenyl-1,2,3,6- tetrahydropyridine). The expression and LRRK2 (leucine-rich repeat kinase 2) were detected mice Human neuroblastoma cell lines SH-SY5Y pretreated with MPP+ (N-methyl-4-phenylpyridinium)....
Bacterial infections remain a significant challenge in clinical medicine, and pervasive bacterial contamination addressed is based on the rational use of biomedical antibacterial materials clinic. While antibiotics have been instrumental mitigating threat infections, overuse has led to emergence antibiotic-resistant bacteria, thus, there an urgent need explore alternative antimicrobial strategies. Gallium (Ga)-based hold tremendous potential due their exceptional properties, which combine...
The tail of imidazole regulated the assembly fascinating 2D sql topology and 3D 2-fold interpenetrated lvt structure polyoxotungstate-based open frameworks with efficient visible-white-light-driven aerobic catalytic oxidation sulfides.