A5058034979- Spinal Fractures and Fixation Techniques
- Spinal Dysraphism and Malformations
- Spine and Intervertebral Disc Pathology
- Cervical and Thoracic Myelopathy
- Cerebrospinal fluid and hydrocephalus
- Spinal Cord Injury Research
- Scoliosis diagnosis and treatment
- Congenital heart defects research
- Head and Neck Surgical Oncology
- Glioma Diagnosis and Treatment
- Connective tissue disorders research
- Spinal Hematomas and Complications
- Pelvic and Acetabular Injuries
- Traumatic Brain Injury and Neurovascular Disturbances
- Nerve Injury and Rehabilitation
- Musculoskeletal pain and rehabilitation
- Plant Molecular Biology Research
- Meningioma and schwannoma management
- Genomic variations and chromosomal abnormalities
- Bone Metabolism and Diseases
- Medical Imaging and Analysis
- Cancer Genomics and Diagnostics
- Sarcoma Diagnosis and Treatment
- Nerve injury and regeneration
- TGF-β signaling in diseases
Capital Medical University
2017-2025
Chinese Institute for Brain Research
2025
Nanjing Tech University
2023-2024
Liaoning Academy of Agricultural Sciences
2022-2023
Ningbo University
2022
Beijing Xuanwu Traditional Chinese Medicine Hospital
2020-2022
Peking Union Medical College Hospital
2015-2020
Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2020
Jining Medical University
2020
ORCID
2020
The aim was to assess the clinical, laboratory and radiological features of SAPHO syndrome.We recruited all patients presenting Peking Union Medical College Hospital from 2004 2015 diagnosed with syndrome. medical data, test results imaging were collected for patients.One hundred sixty-four (111 women 53 men) our cohort. mean age 40.71 years. Nine had osteoarticular symptoms without skin involvement. One forty-three 25 palmoplantar pustulosis severe acne, respectively. Psoriasis vulgaris...
Objective: To compare the efficacy of oblique lateral interbody fusion (OLIF), OLIF combined with anterolateral screw fixation (OLIF-AF), and percutaneous pedicle (OLIF-PF) in treatment single-level or 2-level degenerative lumbar disease.Methods: Between January 2017 2021, 71 patients were treated OLIF. The demographic data, clinical outcomes, radiographic complications compared among 3 groups.Results: operative time intraoperative blood loss (p<0.05) OLIF-AF groups lower than OLIF-PF...
Although cerebrospinal fluid (CSF)-based liquid biopsy was proved to be practical in molecular analysis of intracranial gliomas, primary intramedullary astrocytoma rarely reported. Given the distinct genomic profiles between glioma and astrocytoma, whether feasibility CSF-based gliomas can replicated spinal cord needs investigated. The aim this pilot study is evaluate through sequencing CSF-derived circulating tumor DNA (ctDNA).Two grade IV diffuse midline 1 II, I were included....
Abstract BACKGROUND The management of atlantoaxial dislocation (AAD) associated with basilar invagination (BI) is challenging, and traditional posterior-only approaches lack the ability to release anterior soft tissue resulting in unsatisfactory reduction. Furthermore, vertebral artery anomalies deformed anatomy increase surgical risks. OBJECTIVE To introduce a safe efficient technique reduce congenital AAD BI through single-stage approach. METHODS A total 65 patients concomitant who had...
Chitosan nanoparticles have been recognized as a new type of biomaterials for treatment spinal cord injury (SCI). To develop novel method targeted delivery injured cord, valproic acid labeled chitosan (VA-CN) were constructed and evaluated in the SCI. Our results demonstrated that administration VA-CN significantly promoted recovery function tissue repair after Moreover, we found inhibited reactive astrocytes Furthermore, enhanced immunoreactions neuronal related marker NF160, which...
ABSTRACT Background Iatrogenic cervical kyphosis (ICK) often requires complex anterior and posterior correction, which is associated with multiple complications. Consequently, there a need to investigate alternative treatment approaches that streamline the operative process markedly diminish postoperative This study, therefore, aimed evaluate feasibility efficacy of single‐stage controllable antedisplacement fusion (ACAF) in revision surgeries for ICK. Methods A retrospective review was...
Revision surgery for patients with persistent, recurrent, or progressive syringomyelia following foramen magnum decompression (FMD) Chiari malformation I-syringomyelia (CM-SM) is not uncommon and presents both strategic technical challenges. We conducted a retrospective study including all who underwent revision Cerebellar Tonsillectomy (CTL) CM-SM between 2003 2023. Additionally, we performed uni- multivariate analyses to identify possible factors contributing failed CTL outcomes....
BACKGROUND AND OBJECTIVES: The exact pathways of fluid outflow within the central canal (CC) spinal cord are not completely understood. best management approach for patients with post-traumatic syringomyelia that progresses to cranial end CC, also known as syringobulbia (PT-syringobulbia), is still a topic debate. This study aims introduce new surgical indication foramen magnum and Magendie dredging (FMDD) procedure in PT-syringobulbia prospectively assess its outcomes. METHODS: included 15...
Abstract Background The molecular and genetic mechanisms by which different single nucleotide variant alleles in specific genes, or at the same locus, cause distinct disease phenotypes often remain unclear. Allelic truncating mutations of FBN1 could either classical Marfan syndrome (MFS) a more complicated phenotype associated with Marfanoid–progeroid–lipodystrophy (MPLS). Methods We investigated small cohort, encompassing two MFS one MPLS subjects from China, whose clinical presentation...
OBJECTIVE The treatment of atlantoaxial dislocation (AAD) and basilar invagination (BI) is challenging, especially in symptomatic patients with a history previous surgery. Although seldom reported, posterior revision surgery to revise prior constructs can be advantageous over an anterior or combined approach. authors describe their experience performing using Goel’s technique. METHODS reviewed AAD BI who had undergone at the cranio-cervical junction between January 2016 September 2017. All...