A5053387891- Hydraulic Fracturing and Reservoir Analysis
- Groundwater flow and contamination studies
- Rock Mechanics and Modeling
- Antibiotic Resistance in Bacteria
- Landslides and related hazards
- Advanced biosensing and bioanalysis techniques
- Dam Engineering and Safety
- Biosensors and Analytical Detection
- Advancements in Battery Materials
- Seismic Imaging and Inversion Techniques
- Pharmaceutical and Antibiotic Environmental Impacts
- Enterobacteriaceae and Cronobacter Research
- Higher Education and Teaching Methods
- Advanced Cellulose Research Studies
- Mycotoxins in Agriculture and Food
- Advanced Nanomaterials in Catalysis
- Bacterial biofilms and quorum sensing
- Advanced Battery Materials and Technologies
- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Analytical chemistry methods development
- Nanoplatforms for cancer theranostics
- Soil and Unsaturated Flow
- Antimicrobial Peptides and Activities
- Advanced Chemical Sensor Technologies
Shandong University of Science and Technology
2013-2025
Chongqing University
2025
Heinrich Heine University Düsseldorf
2022-2025
Sichuan Agricultural University
2022-2025
Jiangxi Agricultural University
2025
Hebei University
2023-2025
Chengdu Medical College
2024
Xi'an University of Architecture and Technology
2023-2024
First Affiliated Hospital of Wenzhou Medical University
2020-2024
Chinese Academy of Inspection and Quarantine
2024
Importance Diabetes in children is a global epidemic that causes various medical conditions associated with an increased incidence of premature death. Objective To investigate the trends diabetes incidence, mortality, and disability-adjusted life-years (DALYs) children, risk factors for diabetes-associated death, from 1990 to 2019. Design, Setting, Participants This was cross-sectional study used data Global Burden Diseases (GBD) 2019 204 countries territories. Children who were aged 0 14...
A subcutaneous abscess is a local infection caused by pathogenic bacteria. Due to the emergence of multidrug-resistant (MDR) bacteria, there an urgent need for development new approaches treat abscesses. In recent studies, we determined that ruthenium nanoparticles have high photothermal conversion efficiency and can transfer energy surrounding oxygen molecules generate cytotoxic singlet (ROS). Acetylcholine (Ach) was modified added surface form composite (Ach@RuNPs). played role in...
Abstract The joints are existing throughout the underground rock mass. It is of great significance to investigate shear performance mass maintain stability structure. In this study, we conducted orthogonal tests determine proportion rock-like materials, and used JRC curves make specimen molds then prepare specimens. We straight uniaxial compression various mechanical parameters materials. Next, carried out characteristics specimens, study damage pattern strength jointed under different...
Abstract Interleukin (IL)-17 producing T helper (Th17) cells are major effector in the pathogenesis of rheumatoid arthritis (RA). The P2X7 receptor (P2X7R) has emerged as a potential site regulation inflammation RA but little is known its functional role on differentiation Th17 cells. This study investigates vitro and vivo effects P2X7R cell during type II collagen (CII) induced experimental model. In CII-treated dendritic (DCs) DC/CD4 + coculture system, pretreatment with pharmacological...
Efflux pump system-mediated bacterial multidrug resistance is one of the main causes antibiotic failure.
This study proposes a double-rough-walled fracture model to represent the natural geometries of rough fractures. The surface is generated using modified successive random additions (SRA) algorithm and aperture distribution during shearing calculated mechanistic model. shear-flow simulations are performed by directly solving Navier-Stokes (NS) equations. results show that can improve accuracy fluid flow approximately 14.99%–19.77%, compared with commonly used single-rough-walled ratio rate...
The emergence and spread of carbapenem-resistant Enterobacter cloacae complex (ECC) have posed a serious threat to human health worldwide. This study aimed investigate the molecular mechanism carbapenem resistance its prevalence among ECC in China.A total 1314 clinical isolates were collected from First Affiliated Hospital Wenzhou Medical University 2004 2018. Sensitivity antibiotics was determined using agar dilution method. production carbapenemases resistance-associated genes investigated...
Abstract Background The emergence of carbapenem-resistant and colistin-resistant ECC pose a huge challenge to infection control. purpose this study was clarify the mechanism carbapenems colistin co-resistance in Enterobacter cloacae Complex (ECC) strains. Results This showed that mechanisms carbapenem resistance are: 1. Generating carbapenemase (7 19); 2. production AmpC or ESBLs combined with decreased expression out membrane protein (12 19). hsp60 sequence analysis suggested 10 19 strains...
Purpose: Malignant melanoma (MM), the most lethal skin cancer, is highly invasive and metastatic. These qualities are related to not only genetic mutations in MM itself but also interaction of cells with immune system microenvironment. This study aimed construct a combined immunotherapy gene therapy drug delivery for effective treatment MM. Methods: Mature dendritic cell (mDC) exosomes (mDexos) induction functions were used as carriers. BRAF siRNA (siBRAF) ability silence mutated was...
2062 Background: Glioblastoma Multiforme (GBM) is one of the most deadly cancers, and nearly all patients experience recurrence upon current standard care for newly diagnosed GBM. The recurrent GBM (rGBM) exhibits a median survival less than 8 months with limited therapeutic options. We have previously cloned B7-H3 gene, characterized its function, demonstrated altered expression in human solid tumors, identified as promising target. present herein preliminary findings an...