Christine Cunningham
A5101692543- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Climate Change and Health Impacts
- COVID-19 and Mental Health
- Pharmaceutical Practices and Patient Outcomes
- Streptococcal Infections and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Long-Term Effects of COVID-19
- Machine Learning in Healthcare
- Healthcare cost, quality, practices
- Intensive Care Unit Cognitive Disorders
- Otolaryngology and Infectious Diseases
- Family and Patient Care in Intensive Care Units
- Cardiac Health and Mental Health
- Case Reports on Hematomas
- Antibiotic Use and Resistance
- Pediatric Pain Management Techniques
- Emergency and Acute Care Studies
- Sepsis Diagnosis and Treatment
- Healthcare Policy and Management
- Behavioral Health and Interventions
- Infective Endocarditis Diagnosis and Management
- Scientific Computing and Data Management
- Digital Mental Health Interventions
- Venous Thromboembolism Diagnosis and Management
University of Oxford
2022-2025
Nuffield Health
2022-2024
Lucile Packard Children's Hospital
2018
Institute for Clinical and Economic Review
2016
Scripps Health
2015
Scripps Clinic
2015
New York Chiropractic College
2014
Electronic health records (EHRs) and other administrative data are increasingly used in research to generate evidence on the effectiveness, safety, utilisation of medical products services, inform public guidance policy. Reproducibility is a fundamental step for credibility promotes trust generated from EHRs. At present, ensuring using EHRs reproducible can be challenging researchers. Research software platforms provide technical solutions enhance reproducibility conducted In response...
Objective To investigate the effect of covid-19 pandemic on number patients with group A streptococcal infections and related antibiotic prescriptions. Design Retrospective cohort study in England using OpenSAFELY-TPP. Setting Primary care practices that used TPP SystmOne software, 1 January 2018 to 31 March 2023, approval NHS England. Participants Patients registered at a practice start each month period. missing data for sex or age were excluded, resulting population 23 816 470 2018,...
Study Design. Retrospective review of prospectively collected data. Objective. The study aim was to determine the prevalence vascular complications associated with anterior lumbar interbody fusion (ALIF) as a function anatomic variation and number levels fused. Summary Background Data. ALIF often requires mobilization great vessels, particularly when exposing above L5-S1. exposure can be more challenging in setting spondylolisthesis or transitional anatomy. Methods. This retrospective data...
Background COVID-19 restrictions led to increased reports of depressive symptoms in the general population and impacted health social care services. We explored whether these changes affected antidepressant prescribing trends those with learning disability or autism. Methods With approval NHS England, we used >24 million patients’ primary data from OpenSAFELY-TPP platform. interrupted time series analysis quantify prescribed newly an across key demographic clinical subgroups, comparing...
Sepsis, characterised by significant morbidity and mortality, is intricately linked to socioeconomic disparities pre-admission clinical histories. This study aspires elucidate the association between non-COVID-19 related sepsis health inequality risk factors amidst pandemic in England, with a secondary focus on their 30-day mortality.
The COVID-19 pandemic disrupted cardiovascular disease management in primary care England.
Aims The COVID‐19 pandemic caused significant disruption to routine activity in primary care. Medication reviews are an important care ensuring safety and appropriateness of prescribing. A could have negative implications for patient Using routinely collected data, our aim was first describe codes used record medication review then report the impact on rates reviews. Methods With approval NHS England, we conducted a cohort study 20 million adult records general practice, in‐situ using...
Abstract Background The UK COVID-19 vaccination programme delivered its first “booster” doses in September 2021, initially groups at high risk of severe disease then across the adult population. BNT162b2 Pfizer-BioNTech vaccine was used initially, with Moderna mRNA-1273 subsequently also used. Methods We OpenSAFELY-TPP database, covering 40% English primary care practices and linked to national coronavirus surveillance, hospital episodes, death registry data, estimate effectiveness boosting...
Abstract Background Germ Defence ( www.germdefence.org ) is an evidence-based interactive website that promotes behaviour change for infection control within households. To maximise the potential of to effectively reduce spread COVID-19, intervention needed be implemented at scale rapidly. Methods With NHS England approval, we conducted efficient two-arm (1:1 ratio) cluster randomised controlled trial (RCT) examine effectiveness randomising implementation via general practitioner (GP)...
To test Prezi online presentational software as a learning tool for students enrolled in physiopathology laboratory class. A presentation was created and used place of virtual microscopy scanning digital pathology slide during session attended by total 179 students. Review the normal anatomical features architecture tissue followed an annotated tour covering important aspects its pathologic characteristics. This also accompanied comparisons with abnormal to facilitate student comprehension....
Abstract Background The COVID-19 pandemic created unprecedented pressure on healthcare services. This study aimed to investigate if disease-modifying anti-rheumatic drug (DMARD) safety monitoring was affected during the pandemic. Methods A population-based cohort conducted with approval of NHS England, using OpenSAFELY platform access electronic health record data from 24·2 million patients registered at general practices TPP’s SystmOne software. Patients were included for further analysis...
Electronic health records (EHRs) and other administrative data are increasingly used in research to generate evidence on the effectiveness, safety, utilisation of medical products services, inform public guidance policy. Reproducibility is a fundamental step for credibility promotes trust generated from EHRs. At present, ensuring using EHRs reproducible can be challenging researchers. Research software platforms provide technical solutions enhance reproducibility conducted In response...
The COVID-19 pandemic created unprecedented pressure on healthcare services. This study investigates whether disease-modifying antirheumatic drug (DMARD) safety monitoring was affected during the pandemic.
Abstract Background COVID-19 lockdowns led to increased reports of depressive symptoms in the general population and impacted health social care services people with learning disability autism. We explored whether pandemic had an impact on antidepressant prescribing trends within these population. Methods With approval NHS England, we used >24 million patients’ primary data from OpenSAFELY-TPP platform. identified patients or autism interrupted time series analysis quantify those...
Abstract Background Cardiovascular disease management in primary care England was disrupted during the COVID-19 pandemic. Objective To describe impact of pandemic on blood pressure screening and hypertension management, based upon a national quality scheme (Quality Outcomes Framework, QOF) across key demographic, regional, clinical subgroups. this end, we translated complex schemes from text descriptions into reusable analytic code. Methods With approval NHS England, population cohort study...
Abstract Background The COVID-19 pandemic caused significant disruption to routine activity in primary care. Medication reviews are an important care ensure safety and appropriateness of ongoing prescribing a could have negative implications for patient Aim Using routinely collected data, our aim was i) describe the SNOMED CT codes used report medication review ii) impact on volume variation reviews. Design setting With approval NHS England, we conducted cohort study 20 million adult records...
Abstract Objective To investigate the impact of COVID-19 pandemic on Group A streptococcal (GAS) cases and related antibiotic prescriptions. Design retrospective cohort study with supporting dashboards approval NHS England. Setting Primary care practices in England using TPP SystmOne software from January 2018 through March 2023. Participants Patients included were those registered at a practice for each month period. missing sex or age excluded, resulting population 23,816,470 2018,...