A5112761669- Renal cell carcinoma treatment
- Bladder and Urothelial Cancer Treatments
- Renal and related cancers
- Cancer survivorship and care
- Childhood Cancer Survivors' Quality of Life
- COVID-19 and healthcare impacts
- Cancer Genomics and Diagnostics
- Cancer Immunotherapy and Biomarkers
- Natural Compound Pharmacology Studies
- Climate Change and Health Impacts
- Emotional Intelligence and Performance
- Pancreatic and Hepatic Oncology Research
- Anesthesia and Pain Management
- Antifungal resistance and susceptibility
- Intensive Care Unit Cognitive Disorders
- Poisoning and overdose treatments
- Suicide and Self-Harm Studies
- Posttraumatic Stress Disorder Research
- Public-Private Partnership Projects
- Peptidase Inhibition and Analysis
- Genital Health and Disease
- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- MRI in cancer diagnosis
Erie County Medical Center
2025
The University of Texas MD Anderson Cancer Center
2007-2022
Leeds Teaching Hospitals NHS Trust
2005
University of Leeds
2005
University of Leicester
2005
Renal cell carcinoma (RCC) is an immunogenic and proangiogenic cancer, antiangiogenic therapy the current mainstay of treatment. Patients with RCC develop innate or adaptive resistance to therapy. There a need identify biomarkers that predict therapeutic guide combination We assessed interaction between tumor immune microenvironment determined their impact on clinical outcome. found therapy-treated primary tumors showed increased infiltration CD4(+) CD8(+) T lymphocytes, which was inversely...
Local anesthetics have a broad application for minor and major surgeries, in outpatient inpatient settings. Drug dosing, frequency, duration of action, coadministration with other drugs, are some many factors that must be considered each patient, before drug administration. Like medical treatments, the use local has potential complications, such as anesthetic systemic toxicity (LAST). LAST primarily affects cardiac central nervous systems (CNS), seizures arrest being more time-sensitive...
Background Suicide reduction is government strategy in many countries. We need to quantify the connection between non-fatal self-poisoning and eventual suicide. Aims To determine mortality after an episode of identify predictors death by any cause or Method A retrospective single-group cohort study was undertaken with 976 consecutive patients attending a large accident emergency unit 1985–1986 self-poisoning. Information about deaths determined from Office for National Statistics. Results Of...
This randomized controlled trial examined the quality-of-life benefits of an expressive writing (EW) intervention for patients with renal cell carcinoma (RCC) and identified a potential underlying mechanism efficacy.Patients (N = 277) stage I to IV RCC were randomly assigned write about their deepest thoughts feelings regarding cancer or neutral topics (neutral [NW]) on four separate occasions. Patients completed Center Epidemiologic Studies Depression Scale (CES-D), MD Anderson Symptom...
Objective The purpose of this study was to examine the prevalence posttraumatic stress symptoms (PTSS) in patients with renal cell carcinoma (RCC), associations and co-occurrence between PTSS, depressive, other cancer-related ability a single-item distress question identify PTSS. Methods Patients stage I–IV RCC completed assessments depressive (Center for Epidemiologic Studies Depression Scale), PTSS (Impact Event (MD Anderson Symptom Inventory), fatigue (Brief Fatigue sleep disturbance...
Sepsis, characterised by significant morbidity and mortality, is intricately linked to socioeconomic disparities pre-admission clinical histories. This study aspires elucidate the association between non-COVID-19 related sepsis health inequality risk factors amidst pandemic in England, with a secondary focus on their 30-day mortality.
Objectives To determine the feasibility of obtaining intraoperative contrast‐enhanced ultrasound (CEUS) imaging in patients undergoing open partial nephrectomy for renal cancer. We hypothesize that study was feasible and addition CEUS would improve lesion identification characterization. Methods The population consisted 10 with known mass scheduled ultrasound–guided nephrectomy. After dissection exposure kidney by surgeon, an pre‐ post‐CEUS performed radiologist. Feasibility defined as...
Abstract Background The COVID-19 pandemic disrupted healthcare delivery, including difficulty accessing in-person care, which may have increased the need for strong pharmacological pain relief. Methods With NHS England approval, we used routine clinical data from >20 million general practice adult patients in OpenSAFELY-TPP. Using interrupted time series analysis, quantified prevalent and new opioid prescribing prior to (January 2018-February 2020), during lockdown (March 2020-March 2021)...
You have accessJournal of UrologyKidney Cancer: Advanced II1 Apr 20101800 RETROPERITONEAL LYMPH NODE METASTASIS IN M0 RENAL CELL CARCINOMA Scott Delacroix Jr, Stephen Culp, Jaclyn Jin-Ling Chen, Tamboli Pheroze, Surena Matin, and Christopher Wood JrScott Jr More articles by this author , CulpStephen Culp ChenJaclyn Chen PherozeTamboli Pheroze MatinSurena Matin WoodChristopher View All Author Informationhttps://doi.org/10.1016/j.juro.2010.02.1724AboutPDF ToolsAdd to favoritesDownload...
You have accessJournal of UrologyKidney Cancer: Ablative Therapy (PD51)1 Apr 2019PD51-02 ONCOLOGIC EFFECTIVENESS OF IMAGE GUIDED THERMAL ABLATION FOR RECURRENT RENAL CELL CARCINOMA (RCC) AFTER IPSILATERAL PARTIAL NEPHRECTOMY: TERTIARY CANCER CENTER EXPERIENCE Mohamed Abdelsalam*, Tessa Hudspeth, Sharjeel Sabir, Samuel Kusin, Jose Karam, Surena Matin, Christopher Wood, and Kamran Ahrar Abdelsalam*Mohamed Abdelsalam* More articles by this author , HudspethTessa Hudspeth SabirSharjeel Sabir...
Abstract Background: Penile Cancer (PeCa) is a rare cancer with over 90% squamous cell carcinoma (SCC)histology. Risk factors include human papillomavirus (HPV) infection and phimosis. Molecular oncogenic pathways between HPV-Positive HPV-Negative PeCa are difficult to validate because there few preclinical models of no PeCa. Our goal was establish PeCA patient-derived xenograft (PDX) elucidate the molecular signature for therapeutic benefit. Methods: specimens from penectomies inguinal...
You have accessJournal of UrologyKidney Cancer: Advanced (including Drug Therapy) II (PD40)1 Sep 2021PD40-12 DEFINING THE IMPACT OF PERIOPERATIVE MORBIDITY FROM CYTOREDUCTIVE NEPHRECTOMY ON TIMING SYSTEMIC THERAPY: A CONTEMPORARY SERIES FIVE CENTERS Ashanda Esdaille, Jose Karam, Philippe Spiess, Jay Raman, Pranav Sharma, Bryan Hall, Daniel Shapiro, Wade Sexton, Logan Zemp, Glenn Allen, Andrew Watts, Surena Matin, Christopher Wood, and E. Jason Abel EsdailleAshanda Esdaille More articles by...