A5076096438- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Traditional Chinese Medicine Analysis
- Metabolomics and Mass Spectrometry Studies
- Plant-based Medicinal Research
- Ginseng Biological Effects and Applications
- Pharmacological Effects of Natural Compounds
- Bone Metabolism and Diseases
- Spectroscopy and Chemometric Analyses
- Chromatography in Natural Products
- Phytochemical Studies and Bioactivities
- Analytical Chemistry and Chromatography
- Traditional and Medicinal Uses of Annonaceae
- Liver Disease Diagnosis and Treatment
- Alkaloids: synthesis and pharmacology
- Plant biochemistry and biosynthesis
- Biological and pharmacological studies of plants
- Berberine and alkaloids research
- Microbial Metabolism and Applications
- Sesquiterpenes and Asteraceae Studies
- Flavonoids in Medical Research
- Traditional Chinese Medicine Studies
- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Nephrotoxicity and Medicinal Plants
Zhejiang University of Technology
2018-2025
Pai Chai University
2024
Science and Technology Department of Sichuan Province
2021
Bridge University
2021
Nanjing University of Chinese Medicine
2014-2019
Guangzhou University of Chinese Medicine
2018-2019
China Pharmaceutical University
2018
WuXi AppTec (China)
2018
Xilinx (United States)
2016
Zhejiang University
2008-2013
Dietary supplements containing preparations of ginger roots/rhizomes (Zingiber officinale Roscoe) are being used by consumers, and clinical trials using dietary have been carried out to evaluate their anti-inflammatory or antiemetic properties with inconsistent results. Chemical standardization these products is needed for quality control facilitate the design evaluation data from studies. To address this issue, methods based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) were...
Abstract Background Breast cancer (BC) is the second leading cause of cancer‐related deaths among women, primarily due to metastases other organs rather than primary tumor. Methods In this study, a comprehensive analysis plasma proteomics and metabolomics was conducted on cohort 51 BC patients. Potential biomarkers were screened by Least Absolute Shrinkage Selection Operator (LASSO) regression Random Forest algorithm. Additionally, enzyme‐linked immunosorbent assay (ELISA) kits untargeted...
The root of Achyranthes bidentata Blume (AB) is a well-known traditional Chinese medicine for treating osteoporosis. Plenty studies focused on the pharmacological mechanism whole extract; however, contribution different components to anti-osteoporosis effect remains unknown. aim this study explore crude and salt-processed AB under guidance network pharmacology, metabolomics, microbiomics. First, pharmacology analysis was applied constructing compound-target-disease provide holistic view....
ABSTRACT Gualou‐Xiebai‐Banxia (GXB) decoction shows potential for treating myocardial ischemia (MI), although its underlying mechanism is not fully understood. In this study, a multimodal metabolomics approach, combining gas chromatography–mass spectrometry (GC–MS) and 1 H‐NMR, was employed to investigate the cardioprotective effects of GXB in rat model induced by ligation. ELISA assays HE staining demonstrated that effectively reduced injury, oxidative stress markers, fibrosis. Orthogonal...
ABSTRACT Da‐Huang‐Zhe‐Chong Pills (DHZCPs) have demonstrated efficacy in treating uterine fibroids (UFs), but the mechanisms underlying their action remain unclear. In this study, untargeted serum metabolomic analysis was employed to investigate therapeutic effects of DHZCP a rat model UFs utilizing advanced ultra‐performance liquid chromatography tandem quadrupole time‐of‐flight mass spectrometry (UPLC‐Q‐TOF/MS) and pattern recognition. Histopathological examination through H&E staining...
In this study, a rapid ultra-high performance liquid chromatograph coupled with quadrupole-time-of-flight mass spectrometry (UHPLC-Q-TOF-MS) was used for qualitative analysis of chemical constituents in Fu-Zhu-Jiang-Tang tablets, new six-herb preparation treating type II diabetes.
The pseudoguaianelactones A (1) and B (2), two novel sesquiterpene lactones with an unprecedented [5,7,7] ring system featuring α-methylene-γ-lactone moiety, together a new pseudoguaianelactone C (3) were isolated from the roots of Lindera glauca. Pseudoguaianelactones A-C (1-3) inhibited nitric oxide (NO) production, IC50 values ranging 1.38 to 4.00 μM. Moreover, all compounds significantly suppressed production pro-inflammatory mediators (TNF-α, IL-6, IL-1β PGE2) protein expression enzymes...
Fulvic acid (FA) is a mixture of polyphenolic compounds extracted from humus, peat, lignite, and aquatic environments; it used in traditional medicine to treat digestive tract diseases. The purpose the present study was investigate effect FA on growth performance, inflammation, intestinal microbiota, metabolites Xianju yellow chicken. 240 chickens (age, 524 days) included were randomly categorized into 4 treatments with 6 replicates per treatment 10 birds replicate. Birds received basal diet...