A5100330402- Public Health and Nutrition
- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Pharmacological Effects of Natural Compounds
- Rheumatoid Arthritis Research and Therapies
- Gastric Cancer Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Hepatitis C virus research
- Helicobacter pylori-related gastroenterology studies
- Organ Donation and Transplantation
- Pediatric Hepatobiliary Diseases and Treatments
- Renal Transplantation Outcomes and Treatments
- Gastrointestinal disorders and treatments
- Anesthesia and Pain Management
- Prostate Cancer Diagnosis and Treatment
- Methodologies in Health Research and Practice
- Oral microbiology and periodontitis research
- Heparin-Induced Thrombocytopenia and Thrombosis
- Mesenchymal stem cell research
- Diverse Scientific Research Studies
- Cardiac Ischemia and Reperfusion
- Gallbladder and Bile Duct Disorders
- Respiratory and Cough-Related Research
Queen Elizabeth University Hospital
2020-2025
The University of Texas Southwestern Medical Center
2019-2024
Harold C. Simmons Comprehensive Cancer Center
2024
Agricultural Research Center
2024
Wythenshawe Hospital
2022-2024
Suez Canal University
2015-2024
Benha University
2024
Universitas Batam
2020-2023
Abbott (Sweden)
2023
Baylor University
2023
The NCCN Guidelines for Cancer-Associated Venous Thromboembolic Disease provide strategies the prevention, diagnosis, and treatment of venous thromboembolism (VTE) in adult patients with cancer. VTE is a common life-threatening condition cancer, its management often requires multidisciplinary efforts. panel comprised specialists spanning various fields, including cardiology, hematology, medical oncology, internal medicine, interventional radiology, pharmacology. content featured this issue...
Ex vivo normothermic machine perfusion (NMP) of donor kidneys prior to transplantation provides a platform for direct delivery cellular therapeutics optimize organ quality transplantation. Multipotent Adult Progenitor Cells (MAPC® ) possess potent immunomodulatory properties that could minimize ischemia reperfusion injury. We investigated the potential capability MAPC cells in kidney NMP. Pairs (5) human kidneys, from same donor, were simultaneously perfused 7 hours. Kidneys randomly...
Abstract Ex vivo normothermic perfusion (EVNP) technology is a promising means of organ preservation, assessment, and preconditioning prior to kidney transplantation, which has been pioneered by single group. We describe the challenges setting up clinical EVNP programs in 2 new centers, as well early patient outcomes. Governance, training, logistical pathways are described. In order demonstrate safety proficiency this technique, outcomes also Patient included incidence primary nonfunction,...
Recent studies have identified the 8C alkyl chain methylimidazolium ionic liquid 1-octyl-3-methylimidazolium in environment and its potential to trigger auto-immune liver disease primary biliary cholangitis. The toxicity of a range liquids were therefore examined. Oxygen consumption was rapidly inhibited, with potency increasing length. This preceded caspase 3/7 induction DNA fragmentation. Time- dose-dependent loss dye reduction capacities reflected these effects, >700 fold difference...
A methylimidizolium ionic liquid (M8OI) was recently found to be contaminating the environment and related and/or potentially a component of an environmental trigger for autoimmune liver disease primary biliary cholangitis (PBC). The aims this study were investigate human exposure M8OI, hepatic metabolism excretion. PBC patient control sera screened presence M8OI. Human livers perfused with 50μM M8OI in closed circuit its disposition examined. Metabolism examined cultured hepatocytes...
To assess how centralisation of cancer services via robotic surgery influenced positive surgical margin (PSM) occurrence and its associated risk biochemical recurrence (BCR) in cases pT2 prostate (PC). Retrospective analysis all radical prostatectomy (RP) performed the West Scotland during period from January 2013 to June 2022. Primary outcomes were PSM BCR. The secondary compared impact approach on BCR; length location Propensity score matching Cox regression models using R. A total of, 907...
Penelitian ini menggunakan pendekatan deskriptif kualitatif dengan tujuan menganalisis pelaksanaan dan dampak program tersebut terhadap lingkungan, ekonomi, sosial. Hasil penelitian menunjukkan keberhasilan mencapai 100% dari kriteria yang ditetapkan dalam rencana pascatambang. Populasi sapi meningkat kesehatan baik, pakan seperti rerumputan batang pisang. Pola pemeliharaan mayoritas dilakukan secara ekstensif. Dampak sosial positif terlihat hubungan baik antar peternak, sementara ekonomi...
Pruritus is one of the commonest skin complaints. Peppermint oil can be effective in reducing severity such a condition.The aim this study was to assess efficacy topically applied peppermint treatment chronic pruritus.Fifty selected subjects diagnosed with pruritus due hepatic, renal, or diabetic cause were studied and divided into two groups 25 patients each. Group I instructed hydrate then apply topical oil, while II petrolatum by hand; application done on areas pruritus, twice daily for 2...
In the artisanal gold mining industry, due to use of inefficient amalgamation process, high-grade and an alarming quantity mercury-containing tailings are released environment. Although these pose serious environmental risks, they also represent a potentially lucrative source gold. This study investigates from (ASGM) in Cameroon, employing comprehensive characterization approach that includes physical, chemical, mineralogical analyses, as well hydrometallurgical methods such traditional...
Aim To evaluate the effect of adding low dose trospium chloride with transcutaneous posterior tibial nerve stimulation (TPTNS) in treatment overactive bladder (OAB) females after failure behavioral therapy. Methods We randomized 30 women OAB, two groups: G I received min TPTNS, three times a week; GII TPTNS plus 20 mg daily. OAB Symptom Score questionnaire (OABSS), Incontinence Impact Questionnaire‐short form 7 (IIQ‐7), 3 day voiding diary and urodynamics at weeks 0 8 were evaluated. Results...
In many European countries, restrictions exist around the prescription of anti-tumor necrosis factor (anti-TNF) treatments for rheumatoid arthritis (RA). Eligibility and response to treatment is assessed by using disease activity score 28 (DAS28) algorithm, which incorporates one two inflammatory markers, erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP). Although DAS28-CRP provides a more reliable measure activity, functional variants within CRP gene that affect basal...
MicroRNAs (miRNAs) are short noncoding RNAs which each cause repression of many target genes. Previous work has demonstrated that therapeutic blockade single miRNAs is possible. miR-24-3p and miR-145-5p reported to have a detrimental role in ischemia-reperfusion injury. As the action inhibitory, we hypothesized dual both could synergistically upregulate shared genes.Quantification miRNA expression donated kidneys was performed using polymerase chain reaction (PCR) panels....
In many transplant centers, a recipient body mass index (BMI) >30 kg/m2 would be considered contraindication for pancreas transplantation. This study aims to investigate the impact of BMI on graft outcomes after transplantation.Retrospective data all UK solid organ transplants from 1994 2016 were obtained National Health Service Blood and Transplant Registry, n = 2618. Cases missing excluded, resulting in final cohort 1452. Graft patient survival analysis conducted using Kaplan-Meier plots...