A5001449167- Ophthalmology and Eye Disorders
- Ophthalmology and Visual Impairment Studies
- Pancreatic function and diabetes
- Glaucoma and retinal disorders
- Organ Transplantation Techniques and Outcomes
- Pituitary Gland Disorders and Treatments
- Intraocular Surgery and Lenses
- Transplantation: Methods and Outcomes
- Corneal surgery and disorders
- Organ Donation and Transplantation
- Visual perception and processing mechanisms
- Facial Trauma and Fracture Management
- Cannabis and Cannabinoid Research
- Retinal Diseases and Treatments
- Animal Vocal Communication and Behavior
- Cerebral Venous Sinus Thrombosis
- Ophthalmology and Visual Health Research
- Global Energy and Sustainability Research
- Behavioral and Psychological Studies
- Medical and Biological Sciences
- Diabetes and associated disorders
- Peripheral Nerve Disorders
- Analytical Chemistry and Chromatography
- Plant biochemistry and biosynthesis
- Diabetes Management and Research
Newcastle University
2016-2024
University of Minnesota
2007-2024
University of Newcastle Australia
2020
Freeman Hospital
2018-2020
NHS Blood and Transplant
2018-2020
Clinical Research Institute
2020
University of Arizona
2012-2016
Scottish Government
2015
University of Iowa Hospitals and Clinics
1993-2010
Resonance Research (United States)
2010
Abstract Preventing SARS-CoV-2 infection by modulating viral host receptors, such as angiotensin-converting enzyme 2 (ACE2) 1 , could represent a new chemoprophylactic approach for COVID-19 that complements vaccination 2,3 . However, the mechanisms control expression of ACE2 remain unclear. Here we show farnesoid X receptor (FXR) is direct regulator transcription in several tissues affected COVID-19, including gastrointestinal and respiratory systems. We then use over-the-counter compound...
• The postoperative changes in motor alignment are documented during a twoyear follow-up period. A moderate overcorrection at the initial examination resulted best one to two years after surgery, regardless of intermittency exodeviation or presence amblyopia.
It was proposed that there is no inherent relationship between satisfaction and productivity, relationships the two variables are highly dependent upon performance-reward contingencies . Ninety 5s performed a task for 1 hr. A monetary reward then delivered to 21 of 42 high performers low performers. The next completed self-report measures attitudes same another hour. Correlations self-reports second-hour productivity over all .00. Significant positive correlations, however, were found...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Isolation of Three New Crystalline Antibiotics from Streptomyces1Julius Berger, A. I. Rachlin, W. E. Scott, L. H. Sternbach, and M. GoldbergCite this: J. Am. Chem. Soc. 1951, 73, 11, 5295–5298Publication Date (Print):November 1, 1951Publication History Published online1 May 2002Published inissue 1 November 1951https://pubs.acs.org/doi/10.1021/ja01155a084https://doi.org/10.1021/ja01155a084research-articleACS PublicationsRequest reuse...
There is a need for simple, quantitative and prospective assays islet quality assessment that are predictive of transplantation outcome. The current state-of-the-art athymic nude mouse bioassay costly, technically challenging retrospective. In this study, we report on the ability 2 parameters characterizing human quality: (1) oxygen consumption rate (OCR), measure viable volume; (2) OCR/DNA, fractional viability, to predict diabetes reversal in mice. Results demonstrate probability increases...
Hydrogels based on natural polymers offer a range of properties to mimic the native extracellular matrix, and provide microenvironments preserve cellular function encourage tissue formation. A tri-component hydrogel using collagen, alginate fibrin (CAF) was developed investigated at three collagen concentrations for application as functional matrix analogue. Physical-chemical characterization CAF hydrogels demonstrated thermo-responsive crosslinking capacity physiological conditions with...
Physicians often must make prognostic judgments for critically ill patients, but we know little about how well they can perform this task. We prospectively measured disagreements among different physicians' quantitative 269 sequential admissions to an ICU, and evaluated the accuracy discriminating ability of made by types physicians. Many (44.7%) patients provoked one or more at least 20 percentage points three possible pairings whom physician thought were certain survive did not inspire...
Ex vivo normothermic machine perfusion (NMP) of donor kidneys prior to transplantation provides a platform for direct delivery cellular therapeutics optimize organ quality transplantation. Multipotent Adult Progenitor Cells (MAPC® ) possess potent immunomodulatory properties that could minimize ischemia reperfusion injury. We investigated the potential capability MAPC cells in kidney NMP. Pairs (5) human kidneys, from same donor, were simultaneously perfused 7 hours. Kidneys randomly...
ABSTRACT Background: The Medical Technology Ine (MTI) Photoscreener™ is a new eccentric photoscreener that Is being marketed as device for the detection of amblyogenic factors in preverbal children. purpose this study was to evaluate accuracy MTI Photoscreener11' target population young, healthy Methods: One thousand and three children between age 6 months 59 were photoscreened with Photoscreener™. Nine hundred forty nine included their results compared complete ophthalmologic examination...
Islet transplantation is emerging as a treatment option for selected patients with type 1 diabetes. The limited human islet supply from cadavers and poor yield quality remain substantial impediments to progress in the field. Use of porcine islets holds great promise large-scale application transplantation. Consistent isolation dependent on advances pancreas procurement, preservation, isolation, requiring detailed knowledge pancreatic anatomy. primary aim this study was describe vascular...
Large-angle congenital esotropia is usually managed surgically by either of two fundamentally different approaches: (1) the uniform approach, in which surgery restricted to extraocular muscles (bimedial recessions or monocular recession-resection), (2) selective bimedial are combined with resections one both lateral rectus muscles. We compared surgical results types during a ten-year period for 107 patients, whom 57 underwent recessions, had recession-resections, and 48 received three-...
We examined 333 patients between the ages of 11 and 70 years who underwent strabismus surgery with adjustable sutures over a ten-year period. The type strabismus, number amount adjustments, postoperative drift, complications were evaluated. A large percentage required adjustment to obtain desired position. drift patterns characteristic for each preoperative deviation similar that reported nonadjustable procedures. Adjustable suture techniques especially helpful in selected horizontal...