A5039657849- Hormonal and reproductive studies
- Sexual function and dysfunction studies
- Cardiovascular Health and Disease Prevention
- Cardiovascular Function and Risk Factors
- Dialysis and Renal Disease Management
- Muscle Physiology and Disorders
- Kawasaki Disease and Coronary Complications
- Coronary Artery Anomalies
- Infrared Thermography in Medicine
- Intraoperative Neuromonitoring and Anesthetic Effects
- Pain Management and Treatment
- Iron Metabolism and Disorders
- Bariatric Surgery and Outcomes
- Hippo pathway signaling and YAP/TAZ
- Heme Oxygenase-1 and Carbon Monoxide
- Pressure Ulcer Prevention and Management
- Retinal Imaging and Analysis
- Parkinson's Disease Mechanisms and Treatments
- Reproductive Health and Contraception
- Obesity, Physical Activity, Diet
- Vascular anomalies and interventions
- GDF15 and Related Biomarkers
- Sexuality, Behavior, and Technology
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
Sun Yat-sen University
2014-2025
The First Affiliated Hospital, Sun Yat-sen University
2014-2025
Guangdong Medical College
2025
Stony Brook University
2014
State University of New York
2014
The purpose of this study is to investigate the possible underlying pathogenesis erectile dysfunction(ED) in young men with low risk coronary heart disease and no well-known aetiology. To conduct study, 122 patients ED under age 40 were enrolled, along 33 age-matched normal control subjects. had significantly higher levels systolic blood pressure (SBP), total cholesterol triglyceride, high sensitivity C-reactive protein (hs-CRP), greater carotid intima-media thickness (CIMT) Framingham score...
1. Metformin is an activator of AMP-activated protein kinase (AMPK). Recent studies suggest that pharmacological activation AMPK inhibits cardiac hypertrophy. In the present study, we examined whether long-term treatment with metformin could attenuate ventricular hypertrophy in a rat model. The potential involvement nitric oxide (NO) effects was also investigated. 2. Ventricular established rats by transaortic constriction (TAC). Starting 1 week after TAC procedure, were treated (300 mg/kg...
Our understanding of the weight-outcome association mainly comes from single-time body mass index (BMI) measurement. However, data on long-term trajectories within-person changes in BMI diverse study outcomes are sparse. Therefore, this is to determine associations individual and cardiovascular outcomes.The present analysis was based 4 large prospective cohorts restricted participants aged ≥45 years with at least two measurements. Hazard ratios (HR) 95% confidence intervals(95%CI) for each...
Journal Article Accepted manuscript Giant pseudoaneurysm of the non-coronary sinus Valsalva masquerading a pericardial mass Get access Minjie Wan, Wan Department Medical Ultrasonics, First Affiliated Hospital Sun Yat-Sen University, Guangzhou, China https://orcid.org/0000-0003-3089-5258 Search for other works by this author on: Oxford Academic PubMed Google Scholar Wei Li, Li Fengjuan Yao, Yao Kangni Feng, Feng Cardiac Surgery, Yat-sen Corresponding author. Email: [email protected] and...
Background/Aims: Cyr61-cysteine-rich protein 61 (CCN1/CYR61) is a multifunctional matricellular involved in the regulation of fibrogenesis. Animal experiments have demonstrated that CCN1 can inhibit cardiac fibrosis hypertrophy. However, no study has been conducted to assess relation between serum and prognosis acute heart failure (AHF). Methods: We measured levels 183 patients with AHF, were followed up for 6 months. The associations some clinical covariates, especially left ventricular...
<h3>Introduction and Objectives</h3> There is a close relationship between erectile dysfunction (ED) cardiovascular disease. However, many young patients presenting with ED do not have clinical disease even other well-known causes. We aimed to investigate the underlying pathogenesis of without known aetiology in man low risk coronary heart <h3>Methods</h3> One hundred twenty two 33 normal controls under age 40 years were enrolled. Risk factors for artery disease, endothelial function as...
Aim: Protein-energy malnutrition and cardiovascular (CV) disease predisposes patients with end-stage renal (ESRD) on dialysis to a high risk of early death, but the prognostic value prealbumin (PAB) echocardiographic indices in ESRD treated maintenance peritoneal (PD) remains unclear. Methods: A total 211 PD (mean age 49.2 ± 15.4 years, 51.7% male) were prospectively studied. PAB echocardiography parameters recorded at baseline. Follow-up SD: 33.7 17.3 months) was conducted based hospital...
Background Endurance capacity, assessed by 1000-meter (1000 m) run of male university students, is an indicator cardiovascular fitness in Chinese students physical surveillance. Although related to endothelial function closely patients with diseases, it remains unclear whether endurance capacity correlates function, especially circulating microparticles (EMPs), a new sensitive marker dysfunction young students. The present study aimed investigate the relationship between and Methods...
BACKGROUND The aim of this study was to determine whether polymorphisms the Ras-association domain family 1 isoform A (RASSF1A) gene were associated with ovarian cancer and tumor grade stage, which affect prognosis cancer, in women Southern China. MATERIAL AND METHODS Women from China histologically confirmed, graded staged (n=1,375), cancer-free controls (n=1,227), provided samples peripheral blood. DNA extracted blood samples, five tagging single nucleotide (SNPs) (rs4688728G>T,...
Recently, some data have supported the concept that diabetes is negatively associated with aortic aneurysm. In present study, we aimed to investigate relationship between and cardiac structural functional characteristics, in particular, root dimensions, end-stage renal disease (ESRD) patients.ESRD patients receiving peritoneal dialysis for >3 months were consecutively enrolled. Clinical features echocardiographic parameters analyzed according presence of history. Correlation analyses carried...
Previous studies demonstrated that variants in dipeptidyl aminopeptidase-like protein-6 (DPP6) are involved idiopathic ventricular fibrillation. However, its role early repolarization syndrome (ERS) remains largely elusive. The aim of this study is to determine whether the novel DPP6-L747P variant associated with ERS, and explore underlying mechanisms. In our study, whole genome sequencing was used identify a genetic 4 Chinese families sudden cardiac arrest induced by ERS. Then, wild-type...
Abstract Morphological change in retinal vessel diameters has been reported to be associated with negative cardiovascular outcomes, but its association left ventricular diastolic dysfunction (LVDD) is not clear. This study aimed examine the between echocardiographic markers of LVDD and vascular diameters, untreated masked hypertension (MH). In this observational study, 105 MH patients without other risks were included (mean age 48.4 ± 5.7, female 72.4%). All individuals underwent extensive...
Objective: To explore the effect of 6-minute walk test (6MWT) guided by non-invasive cardiac output on rehabilitation patients with knee osteoarthritis following artificial total arthroplasty. Methods: About 66 planned to undergo arthroplasty were included from March 2019 October 2019, and randomly assigned intervention group or control group. Under guidance a clinical physician, orthopedic cardiologist, home exercise program based 6MWT was formulated for osteoarthritis. The participants...