A5076073011- Lymphoma Diagnosis and Treatment
- Mobile Health and mHealth Applications
- COVID-19 and Mental Health
- Cancer Immunotherapy and Biomarkers
- Health Literacy and Information Accessibility
- Palliative Care and End-of-Life Issues
- Ethics in medical practice
- Disaster Response and Management
- Diet and metabolism studies
- RNA modifications and cancer
- Gastric Cancer Management and Outcomes
- Liver Disease and Transplantation
- Healthcare professionals’ stress and burnout
- Colorectal Cancer Screening and Detection
- Chronic Disease Management Strategies
- Immune Cell Function and Interaction
- Medical Coding and Health Information
- Aging and Gerontology Research
- Cancer-related gene regulation
- Eating Disorders and Behaviors
- CAR-T cell therapy research
- Dietetics, Nutrition, and Education
- Sleep and related disorders
- Ubiquitin and proteasome pathways
- Obesity and Health Practices
Fujian Medical University
2020-2025
E-Da Hospital
2015-2024
I-Shou University
2015-2024
Fujian Provincial Cancer Hospital
2023-2024
Taipei Tzu Chi Hospital
2023-2024
Tzu Chi University
2023-2024
National Taiwan University
2023-2024
Academia Sinica
2023-2024
Hunan Agricultural University
2024
Weifang Medical University
2024
Overseeing proper insulin initiation and titration remains a challenging task in diabetes care. Recent advances mobile technology have enabled new models of collaborative care between patients healthcare providers (HCPs). We hypothesized that the adoption such could help individuals starting basal achieve better glycemic control compared with standard clinical practice.
Abstract Increasing evidence shows that the anti-tumor functions of tumor-infiltrating T lymphocytes (TILs) were inhibited significantly, but underlying mechanisms remain not fully understood. In this study, we found 14-3-3ζ expression was up-regulated in hepatocellular carcinoma (HCC) cells and TILs. TILs with high-expression (14-3-3ζ high ) exhibited impaired activation (CD69), proliferation (Ki67) compared to low Flow cytometry assay showed CD8 + cells, ones higher frequency exhausted...
Background The causal relationships between two specific types of problematic use in internet-related activities [i.e., social media (PSMU) and gaming (PG)] psychological distress remain controversial. present study investigated the temporal PSMU, PG, (i.e., anxiety, depression) university students. Methods Hong Kong Taiwan students [ N = 645; n male 266; mean 20.95 years (SD 5.63)] were recruited for a survey study, with follow-ups at 3, 6, 9 months after baseline assessment. Bergen Social...
Purpose The novel coronavirus disease 2019 (COVID-19) caused psychological distress and changed human living styles. However, rare studies have examined the protective behaviors across different populations. Therefore, present study aimed to assess distress, behaviors, potential predictors of Hong Kong general population, Taiwan healthcare workers, outpatients. Methods A cross-sectional design was used recruit participants from Taiwan. Telephone interviews were carried out for ( n = 1,067;...
TRAP1 is involved in metabolic reprogramming and promotes drug resistance. We aimed to explore whether a novel HSP90 inhibitor, C210, overcomes doxorubicin (DOX) resistance of quiescent breast cancer cells by targeting TRAP1. Breast were induced quiescence hypoxia low glucose. The relationship cell metabolism with was investigated Western blotting, ECAR, OCR, mitochondrial complex activity, proteomic analysis. targets C210 their functions analyzed SPR immunoprecipitation. antitumor effect...
Long non-coding RNAs (lncRNAs) have been reported to play pivotal roles in multiple tumors and can act as tumor biomarkers. In this study, we explored the association of expression an lncRNA, DGCR5 with clinicopathological features prognosis HCC.Expression levels were detected by quantitative real-time PCR (qRT-PCR) clinical data was obtained, including basic information, clinicopathology cancer specific survival rate. Receiver operating characteristic (ROC) curve, Kaplan-Meier methods...
The high relapse and mortality rate of small-cell lung cancer (SCLC) fuels the need for epidemiologic study to aid in its prevention.We included 24 studies from ILCCO collaboration. Random-effects panel logistic regression cubic spline were used estimate effects smoking behaviors on SCLC risk explore their non-linearity. Further, we explored whether was mediated through COPD.Significant dose-response relationships observed all quantitative variables. Smoking pack-years associated with a...
Sarcopenia, highly linked with fall, frailty, and disease burden, is an emerging problem in aging society. Higher protein intake has been suggested to maintain nitrogen balance. Our objective was investigate whether pre-sarcopenia status associated lower intake. A total of 327 community-dwelling elderly people were recruited for a cross-sectional study. We adopted the multivariate nutrient density model identify associations between low muscle mass dietary The general linear regression...
Objective Loneliness is a key social and public health issue, mainly affecting the mental of older adults. The article aimed to explore influence intergenerational support from children on loneliness among Meanwhile, also analyzed moderating effects internet usage distance in this process. Methods Based data received 2018 China Longitudinal Aging Social Survey (CLASS), ordinary least square (OLS) regression model was used analyze Furthermore, Bootstrap method test effect relationship between...
Abstract Marital status have been found as an independent prognostic factor for survival and spousal support could provide a advantage in various cancer types. However, the specific effect of marital on hepatocellular carcinoma (HCC) has not explored detail. In this study, we used Surveillance, Epidemiology End Results program to identify iagnosed with HCC between 1988 2007. Kaplan-Meier methods multivariable Cox regression models were analyze long-term cancer-specific (CSS) outcomes risk...
Objective To evaluate the cost-effectiveness of polatuzumab vedotin–rituximab–cyclophosphamide, doxorubicin and prednisone (pola-R-CHP) in CD20-positive patients with previously untreated diffuse large B-cell lymphoma (DLBCL) China. Design A Markov model was constructed to analyse two strategies DLBCL over a lifetime horizon: (1) pola-R-CHP (2) rituximab, cyclophosphamide, doxorubicin, vincristine (R-CHOP). The clinical outcomes were obtained from POLARIX( NCT03274492 ), SCHOLAR-1, ZUMA-7(...
Objective The goal of this research was to reveal the association between living alone and depressive symptoms in older adults. It also aims explore mediating role social activity adult children’s relationship satisfaction. Ultimately, study seeks add body knowledge for lowering risk depression among people promoting positive aging. Methods Based on information from 2020 China Health Retirement Longitudinal Study, ordinary least square (OLS) regression model propensity score matching (PSM)...
Background/Aims: During the occurrence and progression of hepatocellular carcinoma (HCC), phosphotyrosine phosphatases (PTPs) are usually described as tumor suppressors or proto-oncogenes, to some degree correlated with prognosis HCC. Methods: A total 321 patients from Cancer Genome Atlas (TCGA) database 180 our validated cohort were recruited in this study. Kaplan-Meier, univariate multivariate Cox proportional hazards model used evaluate risk factors for survival. Quantitative real-time...