Denna M. Mkwashapi

ORCID: 0000-0001-6883-1431
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • HIV/AIDS Research and Interventions
  • Global Maternal and Child Health
  • Adolescent Sexual and Reproductive Health
  • Parasitic Infections and Diagnostics
  • Child Nutrition and Water Access
  • Breastfeeding Practices and Influences
  • HIV-related health complications and treatments
  • Healthcare Systems and Reforms
  • Data-Driven Disease Surveillance
  • Pediatric health and respiratory diseases
  • Evolution and Genetic Dynamics
  • Medical Coding and Health Information
  • Gestational Diabetes Research and Management
  • HIV Research and Treatment
  • Animal Disease Management and Epidemiology
  • Microfinance and Financial Inclusion
  • Global Health and Epidemiology
  • Zoonotic diseases and public health
  • Iron Metabolism and Disorders
  • Body Composition Measurement Techniques

National Institute for Medical Research
2013-2023

Kilimanjaro Christian Medical Centre
2023

Makerere University
2022

Understanding the causes of inpatient mortality in hospitals is important for monitoring population health and evidence-based planning curative public care. Dearth information on trends hospital most countries Sub-Saharan Africa has resulted to wide use model-based estimation methods which are characterized by errors. This retrospective analysis used primary data determine cause-specific patterns among deaths Tanzania from 2006-2015.

10.1371/journal.pone.0205833 article EN cc-by PLoS ONE 2018-10-31

Accurate and reliable hospital information on the pattern causes of death is important to monitor evaluate effectiveness health policies programs. The objective this study was assess availability, accessibility, quality mortality data in Tanzania. This cross-sectional involved selected hospitals Tanzania carried out from July October 2016. Review registers forms cover a period 10 years (2006–2015). Interviews with staff were conducted seek as regards tools used record data, recording...

10.1186/s12963-018-0175-3 article EN cc-by Population Health Metrics 2018-11-20

Cryptosporidium epidemiology is poorly understood, but infection suspected of contributing to childhood malnutrition and diarrhea-related mortality worldwide.A prospective cohort 108 women their infants in rural/semi-rural Tanzania were followed from delivery through six months. was determined feces using modified Ziehl-Neelsen staining. Breastfeeding/infant feeding practices queried anthropometry measured. Maternal remained high throughout the study (monthly proportion = 44 63%). Infection...

10.1371/journal.pntd.0003072 article EN cc-by PLoS neglected tropical diseases 2014-10-02

Background Sub-Saharan Africa (SSA) has the highest fertility rates and HIV disease burden globally. However, it is not clear how rapid expansion of anti-retroviral therapy (ART) for impacted gap between HIV-infected uninfected women. We used data from a Health Demographic Surveillance System (HDSS) in north-western Tanzania to explore trends relationship over 25-year period. Methods From 1994 2018, births population denominators HDSS were obtain age-specific (ASFRs) total (TFRs). status was...

10.1371/journal.pone.0281914 article EN cc-by PLoS ONE 2023-02-21

Abstract Background Tanzania Health policy insists on the need to provide all women access contraception despite HIV status. We used data from two epidemiologic serological surveys carried out at different periods of ART provision in rural assess level unmet for modern by status and associated factors. Methods performed secondary analysis conducted Magu Demographic Surveillance System site, Mwanza, Tanzania. Information was derived fertility desire use. Unmet need, status, socioeconomic...

10.1186/s12978-023-01695-9 article EN cc-by Reproductive Health 2023-10-16

<ns4:p><ns4:bold>Background:</ns4:bold> In this paper, we explain how three early career researchers actively engaged community members in their health research projects Kenya, Tanzania and Uganda, what was learnt from the experience. The project Kenya on camel trypanosomiasis role of biting keds (or louse flies) disease transmission. looked at effect human immunodeficiency virus antiretroviral therapy fertility ascertained trends use family planning services amongst women reproductive age....

10.12688/openresafrica.13349.2 article EN cc-by Open Research Africa 2022-06-27

Chronic HIV immune activation alters systemic levels of cytokines regulating appetite and body composition we hypothesized this is contributing to a mild degree cachexia that typically remains undetected during pregnancy in food insecure regions. We developed novel scoring system adapted context included nutritional status (body mass index, mid‐upper arm circumference), anorexia, quality life, hemoglobin, CD4, plasma ghrelin cytokines: IL‐1β, IL‐6, TNF‐α, IFN‐γ, IL‐10. Forty‐four HIV+ (mean...

10.1096/fasebj.28.1_supplement.620.5 article EN The FASEB Journal 2014-04-01

<ns4:p><ns4:bold>Background:</ns4:bold> In this paper, we explain how three early career researchers actively engaged community members in their health research projects Kenya, Tanzania and Uganda, what was learnt from the experience. The project Kenya on camel trypanosomiasis role of biting keds (or louse flies) disease transmission. looked at effect human immunodeficiency virus antiretroviral therapy fertility ascertained trends use family planning services amongst women reproductive age....

10.12688/aasopenres.13349.2 article EN cc-by Open Research Africa 2022-06-27

Background: Fertility is associated with the desire to have children. The impacts of HIV and antiretroviral therapy (ART) on fertility are well known, but their for children less known in Tanzania. We used data from two studies carried out at different periods ART coverage rural Tanzania explore relationship between infection desires men women. Methods: conducted secondary analysis community-based 2012 2017 Magu Health Demographic system site, Information desires, status, social-economic...

10.12688/openresafrica.13432.1 article EN cc-by Open Research Africa 2022-09-14

Breast milk (BM) offers an important immunological bridge from mothers to infants; but BM immunology is incompletely understood. We aimed determine how cytokines and immunoglobulins (Ig) were associated with infant Cryptosporidium infection in a prospective cohort of 108 mother (39% HIV+)/infant pairs. maternal serum was analyzed at month 1, 2, 3, 6 postpartum. Greater IgA, IgM, IgG1, IgG2, IgG3 IgG4 levels consistently lower odds infection, the trend not significant. Absolute cytokine did...

10.1096/fasebj.28.1_supplement.1015.6 article EN The FASEB Journal 2014-04-01

Women in rural and semi‐urban areas of Africa face additional healthcare access barriers affecting birth outcomes HIV‐exposed infants have a poorer prognosis compared to unexposed infants. Our objective was characterize associations between maternal nutritional status during pregnancy HIV+ HIV− women enrolled antenatal clinic cohort northwestern Tanzania. Of the 46 72 HIV−women enrolled, 21 36 delivered at/returned within 48 hours were included analysis. Maternal anthropometrics assessed at...

10.1096/fasebj.27.1_supplement.619.1 article EN The FASEB Journal 2013-04-01

Globally, Cryptosporidium spp. is the most common diarrhea‐causing protozoan infection among children at health facilities. Infection may be asymptomatic or manifest as severe, chronic diarrhea especially in malnourished HIV‐positive individuals. Long‐term physical and cognitive impairment has been associated with infection. The objective of this study was to determine prevalence spp . mothers from birth 6 months, understand how breastfeeding practices relate This prospective cohort 100...

10.1096/fasebj.27.1_supplement.619.2 article EN The FASEB Journal 2013-04-01

Abstract Introduction: Routine patient care data are increasingly used for biomedical research, but such “secondary use” have known limitations, including their quality. When leveraging routine observational developing audit protocols that can maximize informational return and minimize costs is paramount. Methods: For more than a decade, the Latin America East Africa regions of International epidemiology Databases to Evaluate AIDS (IeDEA) consortium been auditing drawn from participating...

10.1017/cts.2023.659 article EN cc-by-nc-nd Journal of Clinical and Translational Science 2023-01-01

<ns4:p><ns4:bold>Background:</ns4:bold> In this paper, we explain how three early career researchers actively engaged community members in health research Kenya, Tanzania and Uganda their projects, what was learnt from the experience. The project Kenya on camel trypanosomiasis role of biting keds (or louse flies) disease transmission. looked at effect human immunodeficiency virus (HIV) antiretroviral therapy fertility ascertained trends use family planning services amongst women reproductive...

10.12688/aasopenres.13349.1 article EN cc-by Open Research Africa 2022-03-16
Coming Soon ...