A5055831817- Gut microbiota and health
- Probiotics and Fermented Foods
- Diet and metabolism studies
- Clostridium difficile and Clostridium perfringens research
- Animal Nutrition and Physiology
- Dietary Effects on Health
- Head and Neck Cancer Studies
- Regulation of Appetite and Obesity
- Biochemical Analysis and Sensing Techniques
- Adipose Tissue and Metabolism
- Cancer-related molecular mechanisms research
- Meat and Animal Product Quality
- Microbial Metabolites in Food Biotechnology
- Ruminant Nutrition and Digestive Physiology
- Peroxisome Proliferator-Activated Receptors
- Plant tissue culture and regeneration
- Metabolism, Diabetes, and Cancer
- Food composition and properties
- Fungal Biology and Applications
- Antimicrobial Peptides and Activities
- Salivary Gland Disorders and Functions
- Gastrointestinal motility and disorders
- Metabolomics and Mass Spectrometry Studies
- Animal Behavior and Welfare Studies
- Polyamine Metabolism and Applications
Nanjing Agricultural University
2016-2025
Département Santé Animale
2025
Jiangxi Provincial Cancer Hospital
2018-2024
Nanchang University
2024
Nanjing University
2024
Tianjin University of Technology
2024
First Affiliated Hospital of Anhui Medical University
2020-2024
Anhui Medical University
2020-2024
China Tobacco
2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2019-2022
A reciprocal cross-fostering model with an obese typical Chinese piglet breed and a lean Western was used to identify genetic maternal effects on the acquisition development gut bacteria from birth until after weaning. Pyrosequencing of 16S rRNA genes results revealed age- diet-dependent bacterial succession process in piglets. During first 3 days birth, community relatively simple dominated by Firmicutes 79% 65% relative abundance for Meishan Yorkshire piglets, respectively. suckling period...
Background The objective of this study was to evaluate the effect a probiotic combination on severity oral mucositis (OM), which is common, unpreventable complication induced by radiochemotherapy in patients with nasopharyngeal carcinoma who undergo concurrent (CCRT). Methods Eligible (n = 99) locally advanced were undergoing CCRT randomly assigned (2:1) receive or placebo during radiochemotherapy, and incidence severe OM (grade 3 higher) primary endpoint. Results Patients taking showed...
Currently, knowledge about the impact of long-term intake high resistant starch diet on pig hindgut microbiota and metabolite profile is limited. In this study, a combination pyrosequencing mass spectrometry (MS)-based metabolomics techniques were used to investigate effects raw potato (RPS, in starch) microbial composition metabolites pig. The results showed that Coprococcus, Ruminococcus, Turicibacter increased significantly, while Sarcina Clostridium decreased relative abundances pigs fed...
Early-life antibiotic interventions can change the predisposition to disease by disturbing gut microbiota. However, impact of antibiotics on microbiota in gastrointestinal tract is not completely understood, although antibiotic-induced alterations distal have been reported. Here, employing a piglet model, microbial composition was analyzed high-throughput 16S rRNA gene sequencing and PICRUSt predictions metagenome function. The present study showed clear spatial variation communities stomach...
Butyrate in the gut of animals has potential properties including regulating innate immune, modulating lipid metabolism, and protecting healthy. So far, only limited information on impact butyrate neonatal is available. This study aimed to investigate effects oral administration sodium (SB) microbiota expression inflammatory cytokine piglets. Ten litters crossbred newborn piglets were randomly allocated SB control (CO) groups, each group consisted five (replicates). Piglets orally...
This present study investigated the changes in bacterial community composition, with an emphasis on Lactobacillus spp. and Streptococcus suis populations as potentially beneficial harmful groups, stomach, jejunum ileum of piglets after weaning (21 days postpartum) by 16S rRNA gene-based methods. Denaturing gradient gel electrophoresis analysis showed that, weaning, predominant bands related to disappeared were replaced potential pathogenic species, such Peptostreptococcus anaerobius,...
The objective of this study was to investigate differences in the faecal microbial composition among Lantang, Bama, Erhualian, Meishan, Xiaomeishan, Duroc, Landrace, and Yorkshire sows explore possible link pig breed with gut community. Among sows, were from same breeding farm feed. Fresh faeces collected three each purebred for microbiota analysis volatile fatty acid (VFA) determination. Denaturing gradient gel electrophoresis (DGGE) revealed that samples Xiaomeishan which different farms,...
Intake of raw potato starch (RPS) has been associated with various intestinal health benefits, but knowledge its mechanism in a long-term is limited. The aim this study was to investigate the effects intake RPS on microbial composition, genes expression profiles colon pigs. Thirty-six Duroc × Landrace Large White growing barrows were randomly allocated corn (CS) and groups randomized block design. Each group consisted six replicates (pens), three pigs per pen. Pigs CS offered...
This study aimed to investigate the effects of dietary fibre sources on gut microbiota in suckling piglets, and test hypothesis that a moderate increase may affect during period. Suckling piglets were fed different fibre-containing diets or control diet from postnatal day 7 22. Digesta samples cecum, proximal colon distal used for Pig Intestinal Tract Chip analysis. The data showed differed source location. alfalfa increased Clostridium cluster XIVb Sporobacter termitidis cecum compared pure...
The diversity of fecal methanogens Erhualian (obese type) and Landrace (lean pigs was examined using separate 16S rRNA gene libraries for each breed. A total 763 clones were analyzed; 381 from the library 382 identified belonging to genus Methanobrevibacter. Others Methanosphaera. two showed significant differences in (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mrow><mml:mi>P</mml:mi><mml:mo><</mml:mo><mml:mn>0.05</mml:mn></mml:mrow></mml:math>) composition...
In modern swine husbandry systems, antibiotics have been used as growth promoters for piglets during suckling or weaning period. However, while early colonization of intestinal microbiota has regarded crucial the host's later life performance and well-being, little is known about impact on in piglets. The present study aimed to investigate effects exposure gut microbial metabolism Sixteen litters were fed a creep feed diet with (Antibiotic) without (Control) from postnatal days 7-23 (n = 8)....
This study aimed to determine the effects of early antibiotic intervention (EAI) on subsequent blood parameters, apparent nutrient digestibility, and fecal fermentation profile in pigs with different dietary crude protein (CP) levels. Eighteen litters piglets (total 212) were randomly allocated 2 groups fed a creep feed diet or without in-feed antibiotics (olaquindox, oxytetracycline calcium kitasamycin) from postnatal d 7 42. On 42, within control group mixed, respectively, then further...
Short-chain fatty acids (SCFAs), particularly butyrate, are known to suppress inflammation, and regulate the gut bacterial ecology. However, little is about propionate. We report here that propionate infusion in caecum dramatically affected structure of colonic microbiota pigs based on 16s rRNA high-throughput sequencing. Sixteen pig models were perfused with saline or sodium by a fistula caecum. At d 28, all slaughtered for analysing metabolites, expression genes related inflammation. The...
As a non-ruminant herbivore, the white rhinoceros has ability to utilize fibrous plant matter through microbial fermentation in hindgut. So far, there been no report using molecular techniques study gut microbiota of rhinoceros. We used barcoded pyrosequencing characterize 105,651 sequences 16S rRNA genes obtained from fecal samples five rhinoceroses. Results showed that Firmicutes and Bacteroidetes were predominant phyla samples, which comprised largely unclassified bacteria. The one animal...
Gut methanogenic archaea of monogastric animals are considered to be related energy metabolism and adipose deposition the host; however, information on their development in young piglets is limited. Thus, investigate early colonisation faeces Meishan Yorkshire piglets, faecal samples were collected from at 1, 3, 7, 14 days after birth used analyse community with 16S rRNA gene pyrosequencing. Results showed that diversity neonatal decreased one age, as total methanogen populations increased....