A5010141488- Ovarian function and disorders
- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Genomics and Phylogenetic Studies
- Ovarian cancer diagnosis and treatment
- Lipid metabolism and disorders
- Reproductive System and Pregnancy
- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Plant biochemistry and biosynthesis
- Reproductive Health and Technologies
- Seed and Plant Biochemistry
- Traditional Chinese Medicine Analysis
- Metabolomics and Mass Spectrometry Studies
- HIV, Drug Use, Sexual Risk
- Plant and Fungal Species Descriptions
- Plant Gene Expression Analysis
- Retinal Diseases and Treatments
- Sperm and Testicular Function
- Physiological and biochemical adaptations
- Pharmacological Effects of Natural Compounds
- Identification and Quantification in Food
- Animal Vocal Communication and Behavior
- Phytochemistry and Biological Activities
- Insect and Pesticide Research
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2025
Guangdong Academy of Medical Sciences
2022-2025
Guangdong Provincial People's Hospital
2022-2025
Zhengzhou University
2016-2025
Yunnan Center for Disease Control And Prevention
2006-2025
Southern Medical University
2023-2025
Nanfang Hospital
2024-2025
Anyang Tumor Hospital
2025
Shandong University
2014-2024
Yancheng Third People's Hospital
2022-2024
The transfer of fresh embryos is generally preferred over the frozen for in vitro fertilization (IVF), but some evidence suggests that frozen-embryo may improve live-birth rate and lower rates ovarian hyperstimulation syndrome pregnancy complications women with polycystic ovary syndrome.In this multicenter trial, we randomly assigned 1508 infertile who were undergoing their first IVF cycle to undergo either fresh-embryo or embryo cryopreservation followed by transfer. After 3 days...
Embryo selection with preimplantation genetic testing for aneuploidy (PGT-A) may improve pregnancy outcomes after initial embryo transfer. However, it remains uncertain whether PGT-A improves the cumulative live-birth rate as compared conventional in vitro fertilization (IVF).
To study and compare the outcome of micropulse transscelral cyclophotocoagulation in pediatric glaucoma patients to that adult patients.Consecutive who received between July 2015 December 2016 at University California, San Francisco were retrospectively analyzed. All cases had least 12 months follow-up.Nine eyes from 9 27 25 included. The sample size group is small because MP-TCP was not offered after unsatisfactory results initial cases. Preoperatively, mean intraocular pressure (IOP)...
Abstract Perilla is a young allotetraploid Lamiaceae species widely used in East Asia as herb and oil plant. Here, we report the high-quality, chromosome-scale genomes of tetraploid ( frutescens ) AA diploid progenitor citriodora ). Comparative analyses suggest post Neolithic allotetraploidization within 10,000 years, nucleotide mutation 10% more than diploid, both which are dominated by G:C → A:T transitions. Incipient diploidization characterized balanced swaps homeologous segments,...
The clustered regularly interspaced short palindromic repeat/CRISPR-associated protein 9 (CRISPR/Cas9) technology is an efficient genome editing tool used in multiple plant species. However, it has not been applied to Tartary buckwheat (Fagopyrum tataricum), which important edible and medicinal crop rich rutin other flavonoids. FtMYB45 R2R3-type MYB transcription factor that negatively regulates flavonoid biosynthesis buckwheat. Here, the CRISPR/Cas9 system polycistronic tRNA-sgRNA...
Dating back to the first epidemic among injection drug users in 1989, Yunnan province has had highest number of human immunodeficiency virus type 1 (HIV-1) infections China. However, molecular epidemiology HIV-1 not been fully characterized.Using immunoassays, we identified 103,015 accumulated cases between 1989 and 2004. We studied 321 patients representing Yunnan's 16 prefectures from four risk groups, 11 ethnic populations, ten occupations. three major circulating subtypes:...
Are there any correlations between the phenotypes of polycystic ovary syndrome (PCOS) and genotypes PCOS susceptibility single nucleotide polymorphisms (SNPs) in THADA, DENND1A LHCGR? The genes, THADA DENND1A, carry risk alleles that are associated with endocrine metabolic disturbances patients PCOS. is a heterogeneous endocrinopathy characterized by oligo-anovulation, hyperandrogenism ovaries. In previous genome-wide association study, SNP variants rs13429458, rs12478601, rs2479106,...
Objective: To investigate whether obstetric complications and perinatal outcomes after frozen embryo transfer (FET) in programming cycles differ from that natural cycles. Methods: we conducted a retrospective cohort study collecting total of 14373 singletons born at the center for reproductive medicine affiliated to Shandong university, September 2013 2018. Women were divided into two groups according regimens endometrium preparation: either (n=10211) or (n=4162). The primary incidence...
Polycystic ovary syndrome (PCOS) is the most common reason of anovulatory infertility. Environmental factor one main causes PCOS, but its contribution to ovulatory dysfunction in PCOS remains unknown.A total 2217 infertile women diagnosed as according Rotterdam criteria were recruited, including 1979 with oligo-anovulation (OA group) and 238 normal -anovulation (non OA group). Besides, 279 healthy control reproductive age enrolled controls.Frequencies snoring (PCOS-OA group, PCOS-non-OA...
Tartary buckwheat (Fagopyrum tataricum) not only provides a supplement to primary grain crops in China but also has high medicinal value, by virtue of its rich content flavonoids possessing antioxidant, anti-inflammatory, and anticancer properties. Light is an important environmental factor that can regulate the synthesis plant secondary metabolites. In this study, we treated tartary seedlings with different wavelengths light found red blue could increase expression genes involved flavonoid...
Artemisinin, which has been isolated from Artemisia annua L., is the most effective antimalarial drug and saved millions of lives. In addition, artemisinin its derivatives have anti-tumor, anti-parasitic, anti-fibrosis, anti-arrhythmic properties, enhances demand for these compounds. Improving content in A. therefore becoming an increasing research interest, as chemical synthesis this metabolite not viable. Ultraviolet B C irradiation reported to improve annua, but they are harmful plant...
Polycystic ovary syndrome (PCOS) is one of the most common endocrine metabolic disorders characterized by hyperandrogenism, polycystic ovaries and ovulatory dysfunction. Several studies have reported that aberrant expression miRNAs contributes a lot to disordered folliculogenesis in PCOS, though role underlying mechanism microRNA-200b (miR-200b) microRNA-200c (miR-200c) development PCOS remain unclear.The miR-200b granulosa cells (GCs) derived from 90 patients 70 controls was analyzed using...
Do oral contraceptives (OCs) and progestins impact live birth rate of IVF when used for cycle scheduling in women with polycystic ovary syndrome (PCOS)? OCs were associated lowered rates pregnancy after fresh embryo transfer, whereas this purpose yield higher than OCs. Due to oligo-menorrhea PCOS, progestin are extensively schedule the start an PCOS. Little is known about effect such pretreatments on outcomes, especially, birth. This was a nested cohort study secondary analysis multicenter...