A5055914720- Sepsis Diagnosis and Treatment
- Intensive Care Unit Cognitive Disorders
- Hemodynamic Monitoring and Therapy
- Acute Kidney Injury Research
- Respiratory Support and Mechanisms
- Nosocomial Infections in ICU
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Renal function and acid-base balance
- Anesthesia and Sedative Agents
- Ultrasound in Clinical Applications
- Trauma and Emergency Care Studies
- Hip and Femur Fractures
- Family and Patient Care in Intensive Care Units
- Clinical Reasoning and Diagnostic Skills
- COVID-19 Clinical Research Studies
- Circadian rhythm and melatonin
- Emergency and Acute Care Studies
- Disaster Response and Management
- Nutrition and Health in Aging
- Sleep and related disorders
- Occupational Health and Safety Research
- Palliative Care and End-of-Life Issues
- Long-Term Effects of COVID-19
Capital Medical University
2016-2025
Capital University
2006-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2020
Zhongda Hospital Southeast University
2020
Suzhou Municipal Hospital
2020
Chinese Medical Doctor Association
2015
Beijing Tongren Hospital
2014
During the spring of 2013, a novel avian-origin influenza A (H7N9) virus emerged and spread among humans in China. Data were lacking on clinical characteristics infections caused by this virus.Using medical charts, we collected data 111 patients with laboratory-confirmed infection through May 10, 2013.Of studied, 76.6% admitted to an intensive care unit (ICU), 27.0% died. The median age was 61 years, 42.3% 65 years or older; 31.5% female. total 61.3% had at least one underlying condition....
Abstract Introduction Early and aggressive volume resuscitation is fundamental in the treatment of hemodynamic instability critically ill patients improves patient survival. However, one important consequence fluid administration risk developing overload (FO), which associated with increased mortality acute kidney injury (AKI). We evaluated impact balance on intensive care unit (ICU) AKI. Methods The data were extracted from Beijing Acute Kidney Injury Trial. This trial was a prospective,...
The prognostic value of extravascular lung water indices (EVLWI) has been widely investigated, which is determined by ultrasound B-lines. However, the clinical B-lines for determining prognosis/intensive care unit (ICU) outcomes in patients with acute respiratory distress syndrome (ARDS) rarely reported. Twenty-one ARDS admitted to ICU Fu Xing Hospital underwent both ultrasonography and pulse index continuous cardiac output (PiCCO) monitoring on first, second, third days after diagnosis....
Sleep deprivation is common in critically ill patients the intensive care unit (ICU). Noise and light ICU reduction plasma melatonin play essential roles. The aim of this study was to determine effect simulated noise on nocturnal sleep quality, compare effectiveness earplugs eye masks quality these conditions healthy subjects.This conducted two parts. In part one, 40 subjects slept under baseline night (NL) by a cross-over design. two, were randomly assigned four groups: NL, NL plus placebo...
Abstract Background Both sepsis and acute respiratory distress syndrome (ARDS) are common severe diseases in the intensive care unit (ICU). There is no large-scale multicenter study to clarify attributable mortality of ARDS among septic patients. This aimed evaluate excess critically ill patients with sepsis. Methods The data were obtained from a multicenter, prospective cohort 18 Chinese ICUs between January 2014 August 2015. population was after ICU admission. categorized into two groups:...
Information about the epidemiology of sepsis in community residents China remains scarce and incomplete. The purpose this study was to describe occurrence rate outcome Yuetan Subdistrict Beijing estimate China.Retrospective cohort study.All public hospitals serving Subdistrict, Beijing.All patients (n = 1,716) meeting criteria for based on American College Chest Physicians/Society Critical Care Medicine consensus definition.None.We screened all adult who were hospitalized from July 1, 2012,...
Abstract Background Acute kidney injury (AKI) commonly occurs in intensive care units (ICUs), leading to adverse clinical outcomes and increasing costs. However, there are limited epidemiological data of AKI the critically ill Beijing, China. Methods In this prospective cohort study 30 ICUs, we screened patients up 10 days after ICU admission. Characteristics were compared between non-AKI, renal replacement therapy (RRT) non-RRT patients. Nomograms logistic regression Cox performed examine...
Background: Mechanically ventilated patients in the intensive care unit (ICU) have high mortality rates. There are multiple prediction scores, such as Simplified Acute Physiology Score II (SAPS II), Oxford Severity of Illness (OASIS), and Sequential Organ Failure Assessment (SOFA), widely used general ICU population. We aimed to establish scores on mechanically with combination these disease severity other features available first day admission. Methods: A retrospective administrative...
Background Surviving sepsis campaign (SSC) bundles have been demonstrated to significantly improve survival in and septic shock patients worldwide. Compliance with these protocols resultant mortality was investigated intensive care units (ICUs) China. Methods Adult severe or treated from September 2007 October 2008 11 ICUs of Chinese teaching hospitals were included. The primary outcome compliance resuscitation management bundles. Secondary outcomes included individual bundle protocol impact...
Abstract Background Malnutrition in intensive care unit (ICU) patients is associated with adverse clinical outcomes. The modified nutrition risk the critically ill score (mNUTRIC) was proposed as an appropriate nutritional assessment tool patients, but it has not been fully demonstrated and widely used. Our study conducted to identify ICU using mNUTRIC explore relationship between 28-day mortality high scores. Methods This a secondary analysis, data were extracted from Beijing Acute Kidney...
Abstract Background Acute kidney injury (AKI) newly-emerged in intensive care unit (ICU), has not been thoroughly studied previous researches, is likely to differ from AKI developed before ICU admission. This study aimed evaluate the incidence, risk factors, clinical features and outcome of new-onset critically ill patients. Methods The data present derived a multicenter, prospective cohort in17 Chinese ICUs (January 2014 - August 2015). survival analysis were assessed. Results A total 3374...
Sepsis is the leading cause of intensive care unit (ICU) admission. The purpose this study was to explore prognostic value Sequential Organ Failure Assessment (SOFA) score, Acute Physiological and Chronic Health Evaluation II (APACHE II) procalcitonin (PCT), albumin (ALB), lactate (LAC) levels in patients with sepsis.Consecutive adult suspected or documented sepsis at ICU admission were recruited. Their basic vital signs related auxiliary examinations determine their PCT ALB APACHE score...
In China, increasing attention has been devoted to the patient safety culture within health administrative departments and healthcare organizations. However, no official version of a assessment tool published or is widely used, little known about status in Chinese hospitals. The aims this study were examine reliability validity Safety Attitudes Questionnaire establish benchmark data on Beijing.Across-sectional survey was conducted from August October 2014 using Chinese. Using stratified...
Background: Sepsis is a main cause of morbidity and mortality in critically ill patients. The epidemiology sepsis high-income countries well-known, but information on middle- or low-income still deficient, especially China. purpose this study was to explore the prevalence, characteristics, risk factors, treatment, outcomes patients tertiary hospitals Methods: A multicenter prospective observational cohort performed with consecutively collected data from adults who stayed any intensive care...
Sepsis-3 proposed a new definition of septic shock that excluded patients without hyperlactacidemia. The data from China might help to elucidate the prognosis this special patient group.To study clinical and factors affecting with sepsis based on Chinese intensive care units (ICUs).We conducted retrospective, multicentre observational in larger cohort January 1, 2014 August 31, 2015. were divided into four groups according presence or absence hypotension/vasopressor delivery...
Both sepsis and AKI are diseases of major concern in intensive care unit (ICU). This study aimed to evaluate the excess mortality attributable for acute kidney injury (AKI).A propensity score-matched analysis on a multicenter prospective cohort 18 Chinese ICUs was performed. Propensity score sequentially conducted match patients with without day 1, 2, 3-5. The primary outcome hospital death patients.A total 2008 (40.9%) were eligible study. Of 1010 sepsis, 619 (61.3%) matched whom did not...
Background: China's aging population and increasing demand for critical care pose significant challenges to ICU quality improvement (QI). This study evaluates the impact of a 12-year multicenter QI initiative on performance patient outcomes in context resource constraints. Methods: A pre-post intervention was conducted across 75 ICUs Beijing from January 2011 December 2022. Key interventions included establishment teams, infection prevention protocols, pain sedation management, nutritional...
Early fluid expansion could prevent postoperative organ hypoperfusion. However, excessive resuscitation adversely influences multiple systems. This retrospective, observational study aimed to investigate the relationship between early negative balance and mortality in critically ill adult patients following cardiovascular surgery.In total, 567 who had undergone surgery whose intensive care unit length of stay (LOS) was more than 24 hours were enrolled. The baseline characteristics, daily...
We aimed to evaluate the accuracy of quick Sequential (sepsis-related) Organ Failure Assessment (qSOFA) for diagnosis sepsis-3, and analyze prognosis infected patients in wards over-diagnosed with qSOFA but missed by those accordance sepsis-3 criteria. also intended validate performance as one predictor outcome suspicion infection.We reviewed medical records 1,716 adult infection who were hospitalized from July 1st, 2012 June 30th, 2014 Yuetan subdistrict Beijing, China. Based on criteria...