A5079154374- Plant Stress Responses and Tolerance
- Photosynthetic Processes and Mechanisms
- Toxic Organic Pollutants Impact
- Plant tissue culture and regeneration
- Plant Molecular Biology Research
- Silicon Effects in Agriculture
- Research in Cotton Cultivation
- Transgenic Plants and Applications
- Pharmacological Effects of Natural Compounds
- Plant Reproductive Biology
- Per- and polyfluoroalkyl substances research
- Vector-Borne Animal Diseases
- Cancer-related molecular mechanisms research
- Immunotoxicology and immune responses
- Air Quality and Health Impacts
- Immune Response and Inflammation
- Neuroinflammation and Neurodegeneration Mechanisms
- MicroRNA in disease regulation
- Plant-Microbe Interactions and Immunity
- Plant nutrient uptake and metabolism
- Immune cells in cancer
- Environmental Toxicology and Ecotoxicology
- Cardiovascular and Diving-Related Complications
- Plant responses to elevated CO2
- Viral gastroenteritis research and epidemiology
Shihezi University
2016-2025
Shaoxing People's Hospital
2022-2024
Shaoxing University
2024
Chinese PLA General Hospital
2024
Huawei Technologies (China)
2023
Xinqiao Hospital
2021-2022
Army Medical University
2021-2022
Xinjiang Production and Construction Corps
2022
Zhejiang University of Technology
2018-2021
Binzhou People's Hospital
2017-2021
MicroRNAs (miRNAs) are a large family of small, non-coding RNAs that play pivotal role in tumorigenesis. miR‑34a, which is member the miR-34 family, downstream target p53. Increasing evidence shows miR-34a dysregulation may contribute to tumor development and progression numerous cancers, including esophageal squamous cell carcinoma (ESCC). However, mechanism regulation ESCC cells need be further elucidated because complex regulative network miRNAs. The expression samples has been confirmed...
The triglyceride-glucose (TyG) index has been proposed as a convincing indicator of insulin resistance and found to be associated with atherosclerosis among diabetic patients. However, the relationship between TyG arteriosclerosis in subjects prediabetes new-onset type 2 diabetes (T2D) remains uncertain. purpose this study was assess degree carotid plaque burden patients T2D investigate association population.This cross-sectional observational that included 716 aged 40-70 years old or T2D....
Dehydrins are late embryogenesis abundant proteins that help regulate abiotic stress responses in plants. Overexpression of the Saussurea involucrata dehydrin gene SiDHN has previously been shown to improve water-use efficiency and enhance cold drought tolerance transgenic tobacco. To understand mechanism by which exerts its protective function, we transformed into tomato plants (Solanum lycopersicum L.) assessed their response stress. We observed stresses, had increased contents chlorophyll...
Abstract Background Quercetin is a flavonol compound widely distributed in plants that possesses diverse biological properties, including antioxidative, anti-inflammatory, anticancer, neuroprotective and senescent cell-clearing activities. It has been shown to effectively alleviate neurodegenerative diseases enhance cognitive functions various models. The immune system implicated the regulation of brain function abilities. However, it remains unclear whether quercetin enhances by interacting...
Glycyrrhiza uralensis contains many secondary metabolites with a wide range of pharmacological activities. Drought stress acts as positive regulator to stimulate the production medicinal active component in G. uralensis, however, underlying mechanism remains unclear. The aim this work is investigate accumulation and regulatory pharmaceutical ingredients under drought stress. materials aerial underground parts seedlings treated by 10% PEG6000 for 0, 2, 6, 12, 24 h were used RNA sequencing...
Abstract Background Tomatoes ( Lycopersicon esculentum Mill) are key foods, and their molecular biology evolution have been well described. Tomato plants originated in the tropics and, thus, cold sensitive. Results Here, we generated LeGPA1 overexpressing RNA-interference (RNAi) transgenic tomato plants, which then used to investigate function of response stress. Functional was detected at plasma membrane, endogenous highly expressed roots leaves. Cold treatment positively induced expression...
Abstract Background Saussurea involucrata survives in extreme arctic conditions and is very cold-resistant. This species grows rocky, mountainous areas with elevations of 2400–4100 m, which are snow-covered year-round subject to freezing temperatures. S. ’s ability survive an low-temperature environment suggests that it has particularly high photosynthetic efficiency, providing a magnificent model, rich gene pool, for the analysis plant cold stress response. Fructose-1, 6-bisphosphate...
Glycyrrhizic acid (GA), a saponin compound often used as flavoring agent, can elicit anti-inflammatory and anti-tumor effects, alleviate aging. However, the specific mechanism by which GA alters immune cell populations to produce these beneficial effects is currently unclear.In this study, we systematically analyzed single-cell sequencing data of peripheral blood mononuclear cells from young mice, aged GA-treated mice. Our in vivo results show that reduced senescence-induced increases...
Peroxiredoxin (Prx) plays a role in maintaining the balance of intracellular reactive oxygen species. The peroxidase SiPrx gene from Tianshan Snow Lotus (Saussurea involucrata) has been proved to significantly enhance stress resistance plants. In this study, was expressed heterogeneously high-quality herbage Silphium perfoliatum L. (SP). After treatment with NaCl, transgenic SP only exhibited partial leaf wilting, whereas wild-type (WT) plants were on brink death. Simultaneously,...
Increase in the consumption of natural rubber (NR) has necessitated identification alternative sources NR. The quality NR produced by Taraxacum koksaghyz Rodin (TKS) is comparable to that from Hevea brasiliensis (H.brasiliensis), and therefore, TKS being considered as an source Here, we sequenced root transcriptome after wild seedlings were treated with methyl jasmonate (MeJA) for 0, 6, 24 h. clean reads generated each experimental line assembled into 127,833 unigenes. Kyoto encyclopedia...
Plants have large amounts of the late embryogenesis abundant protein (LEA) family proteins, which is involved in osmotic regulation. The Korla Pear (Pyrus sinkiangensis Yu) an uncommon pear species that thrives Xinjiang and can survive below-freezing conditions. We found PsLEA4 gene was more expressed after cold treatment by looking at transcriptome data Pear. In order to evaluate biological function under low-temperature stress its potential for use agricultural breeding, we cloned from...
High temperatures significantly impair the yield and quality of cotton. Ankyrin-repeat proteins (ANKs) are among largest superfamilies in plants play vital roles both biotic abiotic stress responses. In this study, we identified characterized members cotton ankyrin repeat protein (ANK) gene family, focusing on ANK-TM subfamily member GhANK169, which was highly upregulated RNA-seq data exposed to 42 °C. Overexpression GhANK169 tobacco at °C resulted improved phenotypic resilience, enhanced...
Saussurea involucrata grows in high mountain areas covered by snow throughout the year. The temperature of this habitat can change drastically one day. To gain a better understanding cold response signaling pathways and molecular metabolic reactions involved stress tolerance, genome-wide transcriptional analyses were performed using RNA-Seq technologies. A total 199,758 transcripts assembled, producing 138,540 unigenes with 46.8 Gb clean data. Overall, 184,416 (92.32%) successfully...