Bruna F. Sgardioli

ORCID: 0000-0001-7291-2007
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About
Contact & Profiles
Research Areas
  • Antimicrobial Resistance in Staphylococcus
  • Antimicrobial Peptides and Activities
  • Probiotics and Fermented Foods
  • Milk Quality and Mastitis in Dairy Cows
  • Antimicrobial agents and applications
  • Genomics and Phylogenetic Studies
  • Bacterial Identification and Susceptibility Testing
  • Enterobacteriaceae and Cronobacter Research
  • Biochemical and Structural Characterization
  • Alkaloids: synthesis and pharmacology
  • Chemical Synthesis and Analysis
  • Protein Hydrolysis and Bioactive Peptides

Universidade de São Paulo
2017-2024

Universidade Federal de São Carlos
2017-2024

Universidade dos Açores
2021

Enterococci are gut microbes of most land animals. Likely appearing first in the guts arthropods as they moved onto land, diversified over hundreds millions years adapting to evolving hosts and host diets. Over 60 enterococcal species now known. Two species,

10.1073/pnas.2310852121 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2024-02-28

Antimicrobial peptides can be used systemically, however, their susceptibility to proteases is a major obstacle in peptide-based therapeutic development. In the present study, serum stability of p-BthTX-I (KKYRYHLKPFCKK) and (p-BthTX-I)₂, disulfide-linked dimer, were analyzed by mass spectrometry analytical high-performance liquid chromatography (HPLC). activities assessed determining minimum inhibitory concentrations (MIC) using cation-adjusted Mueller-Hinton broth. Furthermore, biofilm...

10.3390/molecules22111898 article EN cc-by Molecules 2017-11-04

ABSTRACT Enterococci are commensal gut microbes of most land animals. They diversified over hundreds millions years adapting to evolving hosts and host diets. Of 60 known enterococcal species, Enterococcus faecalis E. faecium uniquely emerged in the antibiotic era among leading causes multidrug resistant hospital-associated infection. The basis for association particular species with a is largely unknown. To begin deciphering traits that drive association, assess pool -adapted genes from...

10.1101/2023.05.18.540996 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-05-19
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