Joy Ifunanya Odimegwu

ORCID: 0000-0001-7398-1311
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About
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Research Areas
  • Potato Plant Research
  • Phytochemical Studies and Bioactivities
  • Phytochemistry and Biological Activities
  • Essential Oils and Antimicrobial Activity
  • Phytochemical and Pharmacological Studies
  • Ethnobotanical and Medicinal Plants Studies
  • Drug-Induced Hepatotoxicity and Protection
  • Blood Pressure and Hypertension Studies
  • Cell Image Analysis Techniques
  • Spectroscopy and Chemometric Analyses
  • African Botany and Ecology Studies
  • Complementary and Alternative Medicine Studies
  • Phytochemistry and Bioactive Compounds
  • Cynara cardunculus studies
  • Genetics, Bioinformatics, and Biomedical Research
  • Health Literacy and Information Accessibility
  • Genomics, phytochemicals, and oxidative stress
  • Ginger and Zingiberaceae research
  • Eicosanoids and Hypertension Pharmacology
  • Natural Compound Pharmacology Studies
  • Biomedical Text Mining and Ontologies
  • Social Media in Health Education
  • Herbal Medicine Research Studies
  • Phytochemicals and Medicinal Plants
  • AI in cancer detection

University of Lagos
2013-2023

Central Institute of Medicinal and Aromatic Plants
2013-2023

Rajeev K. Singla Ronita De Thomas Efferth Bruno Mezzetti Md. Sahab Uddin and 95 more Sanusi Sanusi Fidele Ntie‐Kang Dongdong Wang Fabien Schultz Kiran R. Kharat Hari Prasad Devkota Maurizio Battino Daniel Sur Ronan Lordan Sourav S. Patnaik Christos Tsagkaris Siva Sai Chandragiri Surya Kant Tripathi Mihnea‐Alexandru Găman Mosa E.O. Ahmed Elena González-Burgos Smith B. Babiaka Shravan Kumar Paswan Joy Ifunanya Odimegwu Faizan Akram Jesús Simal‐Gándara Mágali S. Urquiza Aleksei Tikhonov Himel Mondal Shailja Singla Sara Di Lonardo Eoghan J. Mulholland Merisa Cenanovic Abdulkadir Yusif Maigoro Francesca Giampieri Soojin Lee Nikolay T. Tzvetkov Anna Maria Louka Pritt Verma Hitesh Chopra Scarlett Perez Olea Johra Khan José M. Álvarez-Suárez Xiaonan Zheng Michał Tomczyk Manoj K. Sabnani Christian Villanueva Garba M. Khalid Hemanth Kumar Boyina Milen I. Georgiev Claudiu T. Supuran Eduardo Sobarzo‐Sánchez Tai-Ping Fan Valeria Pittalà Antoni Sureda Nady Braidy Gian Luigi Russo Rosa Anna Vacca Maciej Banach Gérard Lizard Amira Zarrouk S. Hammami İlkay Erdoğan Orhan Bharat B. Aggarwal George Perry Mark Miller Michael Heinrich Anupam Bishayee Anake Kijjoa Nicolas Arkells David S. Bredt Michaël Wink Bernd L. Fiebich Kiran Gangarapu Andy Wai Kan Yeung Girish Kumar Gupta Antonello Santini Massimo Lucarini Alessandra Durazzo Amr El‐Demerdash Albena T. Dinkova‐Kostova Alejandro Cifuentes Eliana B. Souto Muhammad Asim Masoom Zubair Pravin Badhe Javier Echeverría Jarosław Olav Horbańczuk Olaf K. Horbańczuk Helen Sheridan Sadeeq Muhammad Sheshe Anna Maria Witkowska Ibrahim M. Abu‐Reidah Muhammad Riaz Hammad Ullah Akolade R. Oladipupo Víctor López Neeraj Kumar Sethiya Bhupal Govinda Shrestha Palaniyandi Ravanan Subash C. Gupta

The development of digital technologies and the evolution open innovation approaches have enabled creation diverse virtual organizations enterprises coordinating their activities primarily online. platform titled "International Natural Product Sciences Taskforce" (INPST) was established in 2018, to bring together collaborative environment individuals interested natural product scientific research, empower interactions by using communication tools.In this work, we present a general overview...

10.1016/j.phymed.2022.154520 article EN cc-by-nc-nd Phytomedicine 2022-10-22

Dioscorea species is a very important food and drug plant. The tubers of the plant are extensively used in purposes owing to presence steroidal constituent’s diosgenin tubers. In present study, we report for first time that leaves composita floribunda grown under field conditions exhibited multicellular oil glands on epidermal layers plants using stereomicroscopy (SM) scanning electron microscopy (SEM). Essential was also isolated from otherwise not useful herbage plant, gas...

10.1155/2013/943598 article EN cc-by The Scientific World JOURNAL 2013-01-01

Diuresis refers to an increase in the rate of urine flow and sodium excretion from system via urine. It is a necessary excretory process that may prove difficult for some disease systems e.g. enlarged prostates. Hypertension occurs as result systolic blood pressure higher than 140 mmHg or diastolic 90 mmHg. one most common chronic diseases affecting more billion people worldwide. A high dietary intake factors associated with development hypertension. Clerodendrum chinensis used by local...

10.33140/ajun.06.01.03 article EN Advancements in Journal of Urology and Nephrology 2024-05-27

ABSTRACT Tubers of wild Dioscorea species (yam) are used as low-cost materials for the synthesis steroids; cortisone and progesterone using Marker Degradation chemical route. Decoctions from yam leaves tubers also in ethnomedicine regulating female fertility alleviating painful periods menopausal symptoms. It is now known that tuber extracts reduce inhibit proliferative action breast cancer cells reverse cardiovascular diseases. Due to current urgent needs global interest plants’...

10.1101/2023.04.07.535999 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-04-08

ABSTRACT Diuresis refers to increase in the rate of urine flow and sodium excretion from system via urine. It is a necessary excretory process that may prove difficult for some disease systems e.g. enlarged prostates. Hypertension occurs as result systolic blood pressure higher than 140 mmHg or diastolic 90 mmHg. one most common chronic diseases affecting more billion people worldwide. A high dietary intake factors associated with development hypertension. Clerodendrum chinensis used by...

10.1101/2023.05.09.539974 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-05-10

ABSTRACT Objective We aim to test the efficacy of edible Dioscorea species grown and consumed in Nigeria, Africa on two breast cancer cell lines; MCF-7 MDA-MB231 derived from a luminal triple-negative (TNBC) respectively confirm safety non-tumour cells MCF-10A using well established cytotoxic compound paclitaxel as standard. Metastatic is prevalent cause mortality women around world. Breast therapies have greatly advanced recent years, but many patients develop re-occurrence metastasis...

10.1101/2020.05.08.084269 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2020-05-10

ABSTRACT Thevetia peruviana (Pers.) K.Schum. ( Apocynaceae ) seeds are known to possess cardioactive glycosides such as thevetin A, B, nerifolin etc. They also used locally for general pain relief which there is no scientific evidence our knowledge. Arthralgia regarded generally without inflammation. It endemic in the society and sufferers continue imbibe relieving drugs their tons all over world. Analgesic activity test was carried out using formalin-induced models, at 0.1g, 0.2g 0.3g/kg...

10.1101/2021.07.27.453963 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-07-27

3,3′-Diindolylmethane (DIM) is a compound derived from the digestion of indole-3-carbinol, found in Cruciferous vegetables (Broccoli, Cabbage, Cauliflower,) which promotes Estrogen metabolism females. It has been known to help reduction heavy blood flow during menstruation especially females with uterine fibroids. Dim-plus herbal supplement contains Vitamin E, DIM, Phosphatidlycholine, Spinach, and Broccoli powder. The purpose this research extract identify compounds present Broccoli,...

10.1101/2023.05.09.539959 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-05-10

Starches are important energy sources found in plants with many uses the pharmaceutical industry such as binders, disintegrants, bulking agents drugs and thus require very careful physicochemical analysis for proper identification verification which includes microscopy. In this work, we applied artificial intelligence techniques (using transfer learning deep convolution neural network CNNs to microscopical images obtained from 9 starch samples of different botanical sources. Our approach an...

10.48550/arxiv.2305.05321 preprint EN cc-by-sa arXiv (Cornell University) 2023-01-01

Starches are important energy sources found in plants with many uses the pharmaceutical industry such as binders, disintegrants, bulking agents drugs and thus require very careful physico-chemical analysis for proper identification verification which includes microscopy. We aimed to simplify process of starch by applying artificial intelligence used machine learning.In this work, we applied Artificial Intelligence [AI] techniques (using transfer learning deep convolution neural network...

10.2139/ssrn.4579976 preprint EN 2023-01-01

Abstract Background : Several Dioscorea species are used in Chinese medicine for tumours and grown Africa yet to be tested the best of knowledge efficacy as cytotoxic agents. In Nigeria, greatest producer edible yams world, is king plants. Its tubers feeds millions people also function ethnomedicine diverse diseases. We aim test consumed Nigeria on two breast cancer cell lines; MCF-7 MDA-MB231 derived from a luminal triple-negative (TNBC) respectively confirm safety non-tumour cells MCF-10A...

10.21203/rs.3.rs-16402/v1 preprint EN cc-by Research Square (Research Square) 2020-03-10

ABSTRACT Background The rise in occurrence of hypertension, a non-communicable disease and major factor for chronic renal failure, cardiovascular disease, stroke, which most times lead to sudden death is worrisome. Resistant hypertension more common may have no symptoms at all months or years, but then can cause heart attack, vision kidney damage. Prevention quick management are therefore essential reducing the risk these debilitating ailments. Aqueous ethanolic extracts leaves Clerodendrum...

10.1101/2020.07.18.210070 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-07-21

The rise in the occurrence of hypertension, a non-communicable disease and major factor for chronic renal failure, cardiovascular disease, stroke, which most times lead to sudden death is worrisome.

10.33696/pharmacol.3.023 article EN cc-by Archives of Pharmacology and Therapeutics 2021-04-30
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