A5100749510- Adipose Tissue and Metabolism
- Genomics and Phylogenetic Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Lepidoptera: Biology and Taxonomy
- Diet and metabolism studies
- Plant and animal studies
- Insect-Plant Interactions and Control
- Gut microbiota and health
- Plant-Microbe Interactions and Immunity
- Dietary Effects on Health
- Hepatocellular Carcinoma Treatment and Prognosis
- Advanced biosensing and bioanalysis techniques
- MicroRNA in disease regulation
- Nematode management and characterization studies
- Infant Nutrition and Health
- Exercise and Physiological Responses
- Environmental Quality and Pollution
- Genetics, Aging, and Longevity in Model Organisms
- Water Treatment and Disinfection
- Animal testing and alternatives
- Immunotherapy and Immune Responses
- Cancer, Hypoxia, and Metabolism
- Sirtuins and Resveratrol in Medicine
- Per- and polyfluoroalkyl substances research
- Intracranial Aneurysms: Treatment and Complications
Chinese People's Liberation Army
2022-2025
Chinese PLA General Hospital
2025
Hebei Academy of Agriculture and Forestry Sciences
2023-2025
Ministry of Agriculture and Rural Affairs
2023-2025
Shanghai Medical College of Fudan University
2025
Nanjing Normal University
2025
Tianjin Medical University Cancer Institute and Hospital
2025
Second Hospital of Hebei Medical University
2024
Hebei Medical University
2024
Zhoukou Normal University
2010-2024
Objective Dietary fibre has beneficial effects on energy metabolism, and the majority of studies have focused short-chain fatty acids produced by gut microbiota. Ginseng been reported to aid in body weight management, however, its mechanism action is not yet clear. In this study, we potential modulating effect ginseng microbiota, aiming identify specific strains their metabolites, especially long-chain (LCFA), which mediate anti-obesity ginseng. Design Db/db mice were gavaged with extract...
Increasing energy expenditure through activation of brown adipose tissue (BAT) is a critical approach to treating obesity and diabetes. In this study, rutin, natural compound extracted from mulberry drug used as capillary stabilizer clinically for many years without any side effects, regulated whole-body metabolism by enhancing BAT activity. Rutin treatment significantly reduced adiposity, increased expenditure, improved glucose homeostasis in both genetically obese (Db/Db) diet-induced...
In recent years, there has been a growing demand for rapid detection methods, leading to the proliferation of biosensors, particularly electrochemical which have garnered substantial attention from researchers. The fusion biosensors with advanced sensing technology given rise diverse array characterized by their capabilities and heightened sensitivity. Consequently, an imperative exists comprehensively recapitulate advances in especially within realm clinical medicine. This review aims...
Abstract The integration of Artificial Intelligence (AI) in various sectors has led to significant advancements, with the animal industry being no exception. This review aims investigate benefits, limitations, and future prospects AI technology improving welfare. First, it examines role understanding behaviors emotions, providing deeper insights into their well‐being sources stress. Next, paper explores how can revolutionize nutrition through innovative algorithms data analytics. health...
The gut microbiota are known to play an important role in host health and disease. Alterations the composition can disrupt stability of ecosystem, which may result noncommunicable chronic diseases (NCCDs). Remodeling through personalized nutrition is a novel therapeutic avenue for both disease control prevention. However, whether there commonly used microbiota-targeted diets how microbiota–diet interactions combat NCCDs improve remain questions be addressed. Lactoferrin (LF), broadly dietary...
Abstract Digital transformation and green innovation are powerful initiatives to achieve carbon peaking, neutrality targets high-quality economic development. Using a sample of high energy-consuming listed enterprises from 2012 2021, double fixed-effect model is constructed verify the effect on emission reduction performance enterprises, digital used as moderating variable analyze inner mechanism affecting under transformation. The empirical results show that can significantly improve while...
Abstract As global demand for digital storage capacity grows, technologies based on synthetic DNA have emerged as a dense and durable alternative to traditional media. Existing approaches leverage robust error correcting codes precise molecular mechanisms reliably retrieve specific files from large databases. Typically, are retrieved using pre-specified key, analogous filename. However, these lack the ability perform more complex computations over stored data, such similarity search: e.g.,...
Abstract Jujubae Fructus , the fruit of Ziziphus jujuba Mill has been used as one medicine food homology species for thousands years in China. Studies have shown that active ingredients a variety biological effects, but its role aging process still lacks knowledge. Here, we investigated effect extract (JE) on Caenorhabditis elegans lifespan and potential mechanism. The C. treated with JE was signifificantly increased dose-dependent manner. In addition, treatment prolonged reproductive period...
The bean bug, Riptortus pedestris, has received intense attention in recent years because of its involvement increasing outbreaks staygreen syndrome soybean (Glycine max (L.)), often causing almost 100% loss yield China. However, for this pest great economic importance, potential current and future distribution patterns their underlying driving factors remain unclear.Maxent modelling under climate, elevation land-use (including the information G. max) variables showed that covered a vast...
DJ-1 protein is involved in multiple physiological processes, including Parkinson's disease. However, the role of metabolism largely unknown. Here we found that maintained energy balance and glucose homeostasisvia regulating brown adipose tissue (BAT) activity. DJ-1-deficient mice reduced body mass, increased expenditure improved insulin sensitivity. deletion also resisted high-fat-diet (HFD) induced obesity resistance. Accordingly, transgene triggered autonomous intolerance. Further BAT...
Intermittent fasting (IF), as a dietary intervention for weight loss, takes effects primarily through increasing energy expenditure. However, whether inter-organ systems play key role in IF remains unclear. Here, novel hepatokine, pregnancy zone protein (PZP) is identified, which has significant induction during the refeeding stage of IF. Further, loss function studies and therapeutic experiment mice revealed that PZP promotes diet-induced thermogenesis activating brown adipose tissue (BAT)....
Alcohol is an essential drug in human life with multiple medical functions, but excessive alcohol intake, even a single episode of binge drinking, can cause serious damage. Reducing consumption or absorption direct way to alleviate the related harm. decomposed successively by dehydrogenase (ADH) and acetaldehyde (ALDH) liver. Here, we produced ADH1B (hADH1B)-expressing probiotic, recombinant Lactococcus lactis, that aimed enhance degradation intestinal tract after oral administration. Our...
Bacillus subtilis strain NCD-2 is a promising biocontrol agent for soil-borne plant diseases and shows potential promoting the growth of some crops. The purposes this study were to analyze colonization ability in different crops reveal promotion mechanism by rhizosphere microbiome analysis. qRT-PCR was used determine populations NCD-2, microbial communities' structures analyzed through amplicon sequencing after application NCD-2. Results demonstrated that had good effect on tomato, eggplant...
Purpose Adopting adaptive behavior has become a basic measure for farmers because the increasingly severe climate change is affecting agricultural production. Perception critical first step in adopting behaviors. Livelihood resilience represents farmer's ability to adapt change. Therefore, this article aims explore impact of livelihood and perception on adaptation Qinling Mountains region China. Design/methodology/approach In study, 443 micro-survey data are obtained through one-on-one...
The digital economy serves as a pivotal catalyst for sustainable and eco-friendly development. This study employs suite of advanced econometric models, including the fixed effects, mediation, threshold moderation model, to elucidate intricate dynamics by which influences carbon emissions through lens green innovation. Building on existing research economy, technology innovation emissions, this paper takes dual-innovation perspective divides into disruptive incremental And from government...
Abstract Our previous study has suggested suppressor of cytokine signaling 1 (SOCS1) is associated with clinical progression and functions as an oncogenic role to regulate cell proliferation apoptosis in triple‐negative breast cancer (TNBC). Several microRNA‐messenger RNA (miRNA‐mRNA) relationship databases show SOCS1 identified a direct target gene miRNA‐4458 (miR‐4458). The purpose this was the between miR‐4458 TNBC. In our results, expression decreased TNBC tissues cells compared adjacent...
Obesity and obesity-related metabolic disorders are global epidemics that occur when there is chronic energy intake exceeding expenditure. Growing evidence suggests healthy dietary patterns not only decrease the risk of obesity but also influence composition function gut microbiota. Numerous studies manifest development associated with One promising supplementation strategy modulating microbiota by to combat obesity. In this review, we discuss changes in disorders, a particular emphasis on...
Background Programmed death-1 (PD-1) inhibitors plus tyrosine kinase (TKIs) combination therapy are considered as a first-line treatment recommendation for advanced hepatocellular carcinoma (HCC). However, patients with hyperbilirubinemia excluded from this therapeutic option due to limitations in indications. There is notable absence of published studies evaluating the safety and efficacy PD-1 TKIs HCC combined hyperbilirubinemia. Methods Patients complicated who received were...