A5051948155- Respiratory viral infections research
- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Pediatric health and respiratory diseases
- Contact Dermatitis and Allergies
- RNA and protein synthesis mechanisms
- Mycobacterium research and diagnosis
- Research on Leishmaniasis Studies
- Biosensors and Analytical Detection
- SARS-CoV-2 and COVID-19 Research
- IL-33, ST2, and ILC Pathways
- Eosinophilic Esophagitis
- MicroRNA in disease regulation
- Epigenetics and DNA Methylation
- Neonatal Respiratory Health Research
- Cancer-related molecular mechanisms research
- Dermatology and Skin Diseases
- Inflammatory Bowel Disease
- Leptospirosis research and findings
- Bacteriophages and microbial interactions
- Infectious Encephalopathies and Encephalitis
- Peripheral Neuropathies and Disorders
- Genomic variations and chromosomal abnormalities
- Enterobacteriaceae and Cronobacter Research
National and Kapodistrian University of Athens
2014-2025
Frontier Science Foundation-Hellas
2019
Authorised Association Consortium
2018
Agricultural University of Athens
2012-2015
L-Dopa decarboxylase (DDC) is the most significantly co-expressed gene with ACE2, which encodes for SARS-CoV-2 receptor angiotensin-converting enzyme 2 and interferon-inducible truncated isoform dACE2. Our group previously showed importance of DDC in viral infections. We hereby aimed to investigate expression COVID-19 patients cultured SARS-CoV-2-infected cells, also association ACE2 concurrently evaluated infection- interferon-stimulated ISG56 immune-modulatory, hypoxia-regulated EPO. Viral...
This case-control study was performed to evaluate the association between a specific caspase-9 polymorphism as well genetic -31G/C located in cycle-dependent elements/cell cycle homology regions repressor element of human survivin promoter and risk pancreatic cancer.Eighty patients with cancer 160 healthy controls were investigated for genotype allelic frequencies 1263A/G polymorphisms by Polymerase Chain Reaction-Restriction Fragment Length Polymorphism.The G carrier group allele...
Abstract Background Food protein‐induced allergic proctocolitis (FPIAP) is the leading cause of rectal bleeding in infants. Tolerance presumed to develop until first year age, although natural history studies are scarce, making determination ideal duration for any intervention, challenging. Intestinal microbiota (IM) crucial food allergy development; however, data FPIAP remain limited. This study aimed assess remission after 3 months milk avoidance and its correlation with IM longitudinal...
Immunoglobulin-E(IgE)-mediated hypersensitivity to cow's milk allergens is a frequent cause of severe and life-threatening anaphylactic reactions. Besides case histories controlled food challenges, the detection IgE antibodies specific important for diagnosis cow-milk-specific sensitization. Cow´s allergen molecules provide useful information refined sensitization.A micro-array based on ImmunoCAP ISAC technology was developed designated (MAMA), containing complete panel purified natural...
Background: Immunoglobulin E (IgE)-mediated cow’s milk allergy (CMA) can be life-threatening and affects up to 3% of children. Hypoallergenic infant formulas based on hydrolyzed protein are increasingly considered for therapy prevention allergy. The aim this study was investigate the allergenic activity ability induce T cell cytokine responses an formula extensively (whey) (eHF, formula) supplemented with Galactooligosaccharides (GOS) Limosilactobacillus fermentum CECT5716 (LF) determine its...
The development of methods and miniaturized systems for fast reliable quantitative determinations at the Point-of-Care is a top challenge priority in diagnostics. In this work, compact bench-top system, based on White Light Reflectance Spectroscopy, introduced evaluated an application with high clinical interest, namely determination C-Reactive protein (CRP) human blood samples. system encompassed all necessary electronic optical components performance assay, while dedicated software...
Abstract Foodborne illness is a major cause of morbidity and mortality especially for children, even in the developed world. The aim this study was to assess microbial safety food animal origin intended consumption by children Greece. Sampling involved 8 categories retail products completed with collection 850 samples. These were tested PCR and/or culture Listeria monocytogenes , Campylobacter spp., Escherichia coli O157, Salmonella Cronobacter sakazakii Brucella Mycobacterium avium subsp...
Micro-RNAs (miRNAs) are a class of small non-coding RNA molecules that function though post transcriptional regulation gene expression by process termed interference (RNAi). RNAi–mediated targeting viral RNAs is recognized as an antiviral defense mechanism. The epigenetic effect miRNAs can either be direct, interfering with virus genome, or indirect, through downregulation type I IFN genes. aim this study to identify HRV-A1B specific in human broncheal cell line. In silico prediction...
Abstract Background Four EMA-approved vaccines against SARS-CoV-2 are currently available. Data regarding antibody responses to initial vaccination regimens in patients with inflammatory bowel diseases (IBD) limited. Methods We conducted a prospective, controlled, multicenter study tertiary Greek IBD centers. Participating had completed the (1 or 2 doses, depending on type of COVID-19 vaccine) at least weeks before enrolment. Anti-S1 IgG levels were measured. Demographic and adverse events...
There are few studies about the presence of murine typhus in Greece. Our objective was to conduct a large scale retrospective investigation determine clinical and epidemiological features patients diagnosed with Greece.From 2012 2019 serum samples from hospitalized outpatients throughout Greece suspected for infection were tested by immunofluorescence assay Rickettsia typhi. Immunofluorescence positive obtained since 2016 also qPCR targeting R. Clinical data retrospectively collected...
Background: The susceptibility of the atopic population to respiratory infections (RI) has not been fully elucidated. This is attributed immune dysregulation that characterizes diseases. Although, exact mechanisms involved are understood, there evidence shows maturation innate immunity progresses differently in patients with atopy. Objective: aim study was evaluate viral RIs (VRI) based on number and duration them different age groups subjects atopy without Methods: Seventy-eight (39 healthy...