A5061733121- Retinal and Macular Surgery
- Optical Coherence Tomography Applications
- Retinal Imaging and Analysis
- Tracheal and airway disorders
- Retinopathy of Prematurity Studies
- Retinal Development and Disorders
- Glaucoma and retinal disorders
- Dysphagia Assessment and Management
- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
- Soft Robotics and Applications
- Cardiac, Anesthesia and Surgical Outcomes
- Retinal and Optic Conditions
- Neonatal and fetal brain pathology
- Congenital Heart Disease Studies
- Cerebrovascular and Carotid Artery Diseases
- Infection Control in Healthcare
- Anatomy and Medical Technology
- Cerebral Palsy and Movement Disorders
- Digital Imaging in Medicine
- Aortic aneurysm repair treatments
- Surgical Simulation and Training
- Neonatal Respiratory Health Research
- Reconstructive Facial Surgery Techniques
- Intraocular Surgery and Lenses
Duke University
2022-2025
Baylor College of Medicine
2019-2021
Optical coherence tomography (OCT) systems utilize 2D scanning methods to acquire reflectance-based volumetric images of samples, such as the human retina, with micrometer-scale depth resolution. A common method for performing this at high speeds is use a pair sequential, single-axis galvanometer scanners. An undesired effect using separated scanners variation in beam position pupil plane, phenomenon known wander or wobble. This can lead loss signal and vignetting artifacts resulting images....
Optical coherence tomography (OCT) has revolutionized diagnostics in retinal ophthalmology. Traditional OCT requires minimal relative motion between the subject and scanner, which is difficult to achieve with handheld devices and/or non-stabilized subjects. We recently introduced robotically-aligned (RAOCT) as an alternative that promises alleviate these minimal-movement requirements by tracking compensating for their dynamic hardware components real-time. However, image processing delays...
Cerebral palsy (CP) in infants can affect global motor function and lead to swallowing difficulties. This study aims characterize oral pharyngeal dynamics infancy of patients later diagnosed with CP determine if swallow performance early is associated severity characteristics.This a retrospective chart review who underwent videofluoroscopic studies (VFSS) between 6/2008 10/2018 at tertiary children's hospital, were CP. Demographic data, characteristics metrics, VFSS findings collected...
Infants who undergo congenital heart surgery are at risk of developing vocal fold motion impairment (VFMI) and swallowing difficulties. This study aims to describe the dysphagia in this population explore associations between surgical complexity mobility with airway protection.Retrospective chart review.This is a retrospective review infants (age <12 months) underwent 7/2008 1/2018 received subsequent videofluoroscopic swallow (VFSS). Demographic information, Society Thoracic...
Imaging deep structures with optical coherence tomography (OCT) is difficult in highly scattering biological tissue, such as the sclera. There a need to visualize suprachoroidal space and choroid through sclera study drug delivery.
Background: Mandibular distraction osteogenesis (MDO) is the primary surgical intervention to treat airway obstruction in Pierre Robin sequence (PRS). Current morphologic studies of PRS mandibles do not translate into providing management decisions. We compare infants with nonsyndromic controls characterizing morphological variances relevant distraction. also examine how measurements and grades correlate management. Methods: Patients under 2 months old were age sex matched controls....
Optical coherence tomography (OCT) has revolutionized diagnostics in ophthalmology. However, it requires pa-tient cooperation to fixate on multiple targets and stabilize their head utilizing both chin forehead rests. Patient is particularly important for image montaging, where patients are asked sequentially different regions of interest the retina. These individual volumes then combined into a single large field view volume. To automate OCT acquisition process, we previously developed...
To characterize changes in subfoveal choroidal thickness preterm infants from 30 to 60 weeks' postmenstrual age (PMA).
Ophthalmic optical coherence tomography (OCT) has achieved remarkable clinical success but remains sequestered in ophthalmology specialty offices. Recently introduced robotic OCT systems seek to expand patient access fall short of their full potential due significant imaging workspace and motion planning restrictions. Here, we present a next-generation system capable any head orientation or posture that is mechanically reachable. This overcomes prior restrictions by eliminating fixed-base...
Ophthalmic optical coherence tomography (OCT) has achieved remarkable clinical success but remains sequestered in ophthalmology specialty offices. Recently introduced robotic OCT systems seek to expand patient access fall short of their full potential due significant imaging workspace and motion planning restrictions. Here, we present a next-generation system capable any configuration that is mechanically reachable. This overcomes prior restrictions by eliminating fixed-base tracking...
Suprachoroidal injections are a relatively new method of drug delivery to treat retinal disease. At present, it is difficult visualize the distribution injection-delivered product beneath sclera into suprachoroidal space. Imaging space with OCT hindered by scattering light from densely packed collagen fibers sclera, limiting depth penetration light. In this Letter, we demonstrate first use tartrazine (Yellow 5) as an optical clearing agent for research imaging in
SignificanceImaging deep structures with optical coherence tomography (OCT) is difficult in highly scattering biological tissue, such as the sclera. There a need to visualize suprachoroidal space and choroid through sclera study drug delivery.AimWe aim develop methods image custom-built OCT system delivery within.ApproachWe developed custom handheld scanner anterior segment ex vivo eye models. Tartrazine (Yellow 5) solution, which has been shown optically clear tissue visible regime, was...
Optical coherence tomography (OCT) allows for in vivo imaging of the individual layers retina, but conventional methods do not differentiate outer nuclear layer (ONL) from Henle's fiber (HFL). We have developed a robotically aligned OCT (RAOCT) system capable automatically acquiring volumes at multiple pupil entry positions to reconstruct retinal volume that distinguishes HFL ONL. utilized RAOCT acquire such consented subjects, and used mosaicking combine them into complete show enhanced...
Optical coherence tomography (OCT) revolutionized diagnostics in ophthalmology. Traditional OCT assumes static subjects and produces artifacts during motion. Robotically-aligned mitigates these via hardware motion compensation. However, imperfections result residual error. Here we present a digital correction approach where utilize synchronized sensing of the pupil scanner components to measure state imaging process over time. We subsequently map each A-scan its corresponding location volume...
Introduction: Pierre Robin Sequence (PRS) is described as micrognathia, glossoptosis, and airway obstruction. Various studies utilizing anthropometric analysis, 2-dimensional CT scans and/or linear measurements produced from 3-dimensional images have sought to delineate anatomical differences of the mandible in patients with PRS. Several noted however, no discrete quantitative measure exists defining precise mandibular morphology. The purpose this study was utilize 3D software evaluate...