A5087798505- Assisted Reproductive Technology and Twin Pregnancy
- Prenatal Screening and Diagnostics
- COVID-19 Impact on Reproduction
- Neonatal Respiratory Health Research
- Preterm Birth and Chorioamnionitis
- Ectopic Pregnancy Diagnosis and Management
- Spinal Dysraphism and Malformations
- Pregnancy and preeclampsia studies
- Maternal and Perinatal Health Interventions
- Congenital Anomalies and Fetal Surgery
- Health disparities and outcomes
- Food Security and Health in Diverse Populations
- Urological Disorders and Treatments
- Abdominal Trauma and Injuries
- Pregnancy-related medical research
- Cardiovascular Issues in Pregnancy
- Global Maternal and Child Health
- Trauma and Emergency Care Studies
- Congenital Diaphragmatic Hernia Studies
- Pediatric Urology and Nephrology Studies
- Radio, Podcasts, and Digital Media
- Meta-analysis and systematic reviews
- Cerebrospinal fluid and hydrocephalus
- PARP inhibition in cancer therapy
- Central Venous Catheters and Hemodialysis
University of Cincinnati Medical Center
2019-2025
Cincinnati Children's Hospital Medical Center
2020-2024
University of Cincinnati
2019-2024
Health Service Executive
2023
Good Samaritan Regional Medical Center
2022
Good Samaritan Hospital
2022
Good Samaritan Medical Center
2022
Good Samaritan Hospital Medical Center
2022
Riverside Methodist Hospital
2022
Community Link
2022
Maternal laparotomy-assisted fetoscopic surgery for in-utero myelomeningocele repair has shown that a trans-amniotic membrane suture during port placement can reduce postsurgical complications. Fetoscopic laser photocoagulation (FLP) complex twins is typically performed percutaneously without transmembrane stitch. However, in scenarios placental-free window, maternal laparotomy may be used recipient sac access. Here, we present the outcomes of our series FLP cases, including suturing port.
Normal Saline (NS) and Lactated Ringer's (LR) damage human amniotic epithelium in vitro when compared with a synthetic fluid (Amnio-well, AW). We sought to evaluate the effect of amnio-exchange NS, LR, AW vivo.
To assess whether a history of prior cesarean delivery is associated with an increased risk earlier timing and resultant neonatal morbidity.We performed population-based retrospective cohort study using U.S. birth certificate data, 2012-2016. The population included women one or more deliveries compared referent group parous without delivery. enrich for minimized factors early delivery, we excluded preterm birth, pregnancies complicated by multifetal gestation, pregnancy-induced...
BACKGROUND: Podcasting has become a mainstream media commodity, although its implementation into medical education yet to be studied. curricula can readily created and disseminated for educational efficiency. METHODS: Four podcasts were cover information from American College of Obstetricians Gynecologists’ Practice Bulletins. All residents in our academic program randomized access the bulletins or both bulletins. Both groups offered posteducation quizzes. Outcomes included resident quiz...
To evaluate the impact of amnioinfusion and other peri-operative factors on pregnancy outcomes in setting Twin-twin transfusion syndrome (TTTS) treated via fetoscopic laser photocoagulation (FLP).Retrospective study TTTS FLP from 2010 to 2019. Pregnancies were grouped by volume during (<1 L vs. ≥1 L). The primary outcome was latency surgery delivery. An statistic (AIstat) created for each based fluid infused removed preoperative deepest vertical pocket. Regression analysis planned assess...
To describe the pregnancy outcomes of patients who experienced previable and periviable prelabor rupture membranes (PROM) after treatment twin-twin transfusion syndrome.We conducted a retrospective cohort study whose pregnancies were complicated by syndrome treated with fetoscopic laser photocoagulation at single fetal center subsequently PROM from April 2010 to June 2019. Outcomes infant survival latency delivery. Patients grouped gestational age (before 26 weeks gestation or later). The...
We report a case of twin-twin transfusion syndrome (TTTS) recipient who, after successful fetoscopic surgery, developed large pericardial effusion and calcifications the aorta main pulmonary artery. The donor fetus never had cardiac strain calcifications. A heterozygous likely pathogenic variant in ABCC6 (c.2018T > C, p.Leu673Pro) was identified twin. While TTTS twins are at risk arterial right heart failure secondary to disease, great vessels also observed generalized calcification infancy,...
Fetuses undergo major surgical stress as well fluid shifts secondary to both twin-twin transfusion (TTTS) the fetoscopic surgery for treatment of TTTS. While pathophysiology TTTS is understood, acute metabolic changes that fetuses experience from are not. We sought evaluate in recipient metabolomic profile surgery. Amniotic was collected at beginning and end four cases performed 12/2022-2/2023. Samples were immediately processed evaluated via NMR-based Metabolomics Facility protocol. In...
Background: Significant interplay exists between the amniotic fluid and developing fetus. However true nature of relationship fetus, as well fetal membranes, is very poorly understood due to lack a feasible small animal model for replacement, drainage, or oligohydramnios. We sought create present feasibility rodent exchange. Methods: Pregnant rats underwent midline laparotomy, trans-amniotic suture placement via either U-stitch purse-string. Amniotic was attempted be drained needle,...
The objective of this study was to describe the technical aspects and postnatal neurosurgical outcomes a prenatal, 3-miniport fetoscopic myelomeningocele (MMC) repair technique providing multilayered closure using cryopreserved decellularized human umbilical cord (HUC) matrix allograft for duraplasty.
Objective Prior clinical findings have demonstrated that maternal laparotomy with trans-amniotic trans-uterine suturing of the fetoscopic port site during in utero myelomeningocele repair reduces risk membrane rupture. However, due to laparotomy-associated morbidity, we aimed explore feasibility using a vascular closure device for percutaneous suturing.