A5075605395- Neural dynamics and brain function
- Neural and Behavioral Psychology Studies
- Visual perception and processing mechanisms
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Multisensory perception and integration
- Neuroscience and Neural Engineering
- Visual Attention and Saliency Detection
- Memory and Neural Mechanisms
- Face Recognition and Perception
- Neuroscience and Music Perception
- Memory Processes and Influences
- Psychedelics and Drug Studies
- Neural Networks and Applications
- Cognitive Science and Education Research
- Nicotinic Acetylcholine Receptors Study
- Color perception and design
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Aesthetic Perception and Analysis
- Cognitive Science and Mapping
- Decision-Making and Behavioral Economics
- Categorization, perception, and language
- Psychometric Methodologies and Testing
- Transcranial Magnetic Stimulation Studies
University of California, Santa Cruz
2018-2025
University of Wisconsin–Madison
2015-2020
New York University
2020
University of California, San Francisco
2016-2017
University of Sussex
2016
The physiological state of the brain before an incoming stimulus has substantial consequences for subsequent behavior and neural processing. For example, phase ongoing posterior alpha-band oscillations (8-14 Hz) immediately visual stimulation been shown to predict perceptual outcomes downstream activity. Although this phenomenon suggests that these may phasically route information through functional networks, many accounts treat periodic effects as a consequence activity is independent...
We present a new 3D template atlas of the anatomical subdivisions macaque brain, which is based on and aligned to magnetic resonance imaging (MRI) data set histological sections Saleem Logothetis atlas. describe creation validation that, when registered with structural or functional MRI scans, provides straightforward means estimate boundaries between architectonic areas, either in volume different planes sections, an inflated brain surface (cortical flat map). As such, this intended for use...
Significance Neural oscillations are hypothesized to play an important role in modulating perceptual processing accordance with top-down goals. For instance, the amplitude, phase, and spatial distribution of alpha-band change attention. Given recent links between peak frequency alpha temporal resolution perception, we investigated whether modulation occurs when task demands emphasize integration or segregation visual input over time. We found that occipital–temporal cortex decreased during,...
Many aspects of perception and cognition are supported by activity in neural populations that tuned to different stimulus features (e.g., orientation, spatial location, color). Goal-directed behavior, such as sustained attention, requires a mechanism for the selective prioritization contextually appropriate representations. A candidate attention is alpha band (8-13 Hz), whose power human EEG covaries with focus covert attention. Here, we applied an inverted encoding model assess whether...
Spontaneous fluctuations of neural activity may explain why sensory responses vary across repeated presentations the same physical stimulus. To test this hypothesis, we recorded electroencephalography in humans during stimulation with identical visual stimuli and analyzed how prestimulus oscillations modulate different stages processing reflected by distinct components event-related potential (ERP). We found that strong alpha- beta-band power resulted a suppression early ERP (C1 N150) an...
In the absence of external feedback, a decision maker must rely on subjective estimate their accuracy in order to appropriately guide behavior. Normative models perceptual decision-making relate estimates internal signal quality (e.g., confidence) directly itself, thereby making it unknowable whether or underlying is what drives We constructed stimuli that dissociated human observer's performance visual estimation task from confidence performance, thus violating normative principles. To...
Visual awareness is hypothesized to be intimately related visual working memory (WM), such that information present in WM thought have necessarily been represented consciously. Recent work has challenged this longstanding view by demonstrating stimuli rated observers as unseen can nevertheless maintained over a delay period. These experiments criticized, however, on the basis subjective ratings may contain response bias (e.g., an observer report no when fact they had partial awareness). We...
Transcranial magnetic stimulation (TMS) of human occipital and posterior parietal cortex can give rise to visual sensations called phosphenes. We used near-threshold TMS with concurrent EEG recordings measure how oscillatory brain dynamics covary, on single trials, the perception phosphenes after TMS. Prestimulus power phase, predominantly in alpha band (8-13 Hz), predicted phosphenes, whereas higher-frequency beta-band (13-20 Hz) (but not phase) TMS-evoked responses related phosphene were...
The ability to process and respond external input is critical for adaptive behavior. Why, then, do neural behavioral responses vary across repeated presentations of the same sensory input? Ongoing fluctuations neuronal excitability are currently hypothesized underlie trial-by-trial variability in processing. To test this, we capitalized on intracranial electrophysiology neurosurgical patients performing an auditory discrimination task with visual cues: specifically, examined interaction...
Despite the tangible progress in psychological and cognitive sciences over last several years, these disciplines still trail other more mature identifying most important questions that need to be solved. Reaching such consensus could lead greater synergy across different laboratories, faster progress, increased focus on solving problems rather than pursuing isolated, niche efforts. Here, 26 researchers from field of visual metacognition reached four long-term two medium-term common goals. We...
Abstract Perceptual experience results from a complex interplay of bottom-up input and prior knowledge about the world, yet extent to which affects perception, neural mechanisms underlying these effects, stages processing at two sources information converge, are still unclear. In several experiments we show that language, in form verbal labels, both aids recognition ambiguous “Mooney” images improves objective visual discrimination performance match/non-match task. We then used...
Perception is a probabilistic process dependent on external stimulus properties and one's internal state. However, which states influence perception via what mechanisms remain debated. We studied how spontaneous alpha-band activity (8–13 Hz) pupil fluctuations impact visual detection confidence across contrast levels (i.e., the response function, CRF). In human subjects of both sexes, we found that low prestimulus alpha power induced an “additive” shift in CRF, whereby stimuli were reported...
The amygdala is considered crucial to the formation of emotional episodic memories, but causal evidence in humans limited due challenges non-invasive neuromodulation deep brain structures. In a double-blind, sham-controlled, repeated measures study, we examined whether transcranial low-intensity focused ultrasound (tFUS) targeting left prior encoding and neutral pictures impacted memory for these 24 hours later. We used putative inhibitory tFUS protocol shown attenuate...
Adaptive behaviour depends on the ability to introspect accurately about one's own performance. Whether this metacognitive is supported by same mechanisms across different tasks unclear. We investigated relationship between metacognition of visual perception and short-term memory (VSTM). Experiments 1 2 required subjects estimate perceived or remembered orientation a grating stimulus rate their confidence. observed strong positive correlations individual differences in accuracy two tasks....
Abstract Metacognitive awareness—the ability to know that one is having a particular experience—is thought guide optimal behavior, but its neural bases continue be the subject of vigorous debate. Prior work has identified correlations between perceptual metacognitive and structure function lateral prefrontal cortex (LPFC); however, evidence for causal role this region in promoting metacognition controversial. Moreover, whether LPFC promotes awareness emotional features complex, yet...
Oscillatory neural dynamics are highly non-stationary and require methods capable of quantifying time-resolved changes in oscillatory activity order to understand function. Recently, a method termed 'frequency sliding' was introduced estimate the instantaneous frequency activity, providing means tracking temporal dominant within sub-band field potential recordings. Here, ability sliding recover ground-truth simulated data is tested while exponent (slope) 1/fx component signal power spectrum...
Confidence is an adaptive computation when environmental feedback absent, yet there little consensus regarding how perceptual confidence computed in the brain. Difficulty arises because correlates with other factors, such as accuracy, response time (RT), or evidence quality. We investigated whether neural signatures of accumulation during a choice predict subjective independently these factors. Using motion stimuli, central-parietal positive-going electroencephalogram component (CPP) behaves...